LOCUS BC006463 2034 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens caspase 9, apoptosis-related cysteine peptidase, mRNA
(cDNA clone MGC:2105 IMAGE:3542075), complete cds.
ACCESSION BC006463
VERSION BC006463.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2034)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2034)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: o Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14790123.
FEATURES Location/Qualifiers
source 1..2034
/db_xref="H-InvDB:HIT000032849"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2105 IMAGE:3542075"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2034
/gene="CASP9"
/gene_synonym="APAF-3"
/gene_synonym="APAF3"
/gene_synonym="CASPASE-9c"
/gene_synonym="ICE-LAP6"
/gene_synonym="MCH6"
/db_xref="GeneID:842"
/db_xref="HGNC:HGNC:1511"
/db_xref="MIM:602234"
CDS 96..1346
/gene="CASP9"
/gene_synonym="APAF-3"
/gene_synonym="APAF3"
/gene_synonym="CASPASE-9c"
/gene_synonym="ICE-LAP6"
/gene_synonym="MCH6"
/codon_start=1
/product="caspase 9, apoptosis-related cysteine peptidase"
/protein_id="AAH06463.1"
/db_xref="GeneID:842"
/db_xref="HGNC:HGNC:1511"
/db_xref="MIM:602234"
/translation="MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQ
RAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPT
LENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPC
GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLE
LAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLG
GKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISS
LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVS
VKGIYKQMPGCFNFLRKKLFFKTS"
BASE COUNT 463 a 527 c 570 g 474 t
ORIGIN
1 ggccctgggg cgggggcggg tcctggggac tggggcgggc ggccgaggcc cggaagcgga
61 ctgaggcggc ctggagtctt agttggctac tcgccatgga cgaagcggat cggcggctcc
121 tgcggcggtg ccggctgcgg ctggtggaag agctgcaggt ggaccagctc tgggacgccc
181 tgctgagccg cgagctgttc aggccccata tgatcgagga catccagcgg gcaggctctg
241 gatctcggcg ggatcaggcc aggcagctga tcatagatct ggagactcga gggagtcagg
301 ctcttccttt gttcatctcc tgcttagagg acacaggcca ggacatgctg gcttcgtttc
361 tgcgaactaa caggcaagca gcaaagttgt cgaagccaac cctagaaaac cttaccccag
421 tggtgctcag accagagatt cgcaaaccag aggttctcag accggaaaca cccagaccag
481 tggacattgg ttctggagga tttggtgatg tcggtgctct tgagagtttg aggggaaatg
541 cagatttggc ttacatcctg agcatggagc cctgtggcca ctgcctcatt atcaacaatg
601 tgaacttctg ccgtgagtcc gggctccgca cccgcactgg ctccaacatc gactgtgaga
661 agttgcggcg tcgcttctcc tcgctgcatt tcatggtgga ggtgaagggc gacctgactg
721 ccaagaaaat ggtgctggct ttgctggagc tggcgcagca ggaccacggt gctctggact
781 gctgcgtggt ggtcattctc tctcacggct gtcaggccag ccacctgcag ttcccagggg
841 ctgtctacgg cacagatgga tgccctgtgt cggtcgagaa gattgtgaac atcttcaatg
901 ggaccagctg ccccagcctg ggagggaagc ccaagctctt tttcatccag gcctgtggtg
961 gggagcagaa agaccatggg tttgaggtgg cctccacttc ccctgaagac gagtcccctg
1021 gcagtaaccc cgagccagat gccaccccgt tccaggaagg tttgaggacc ttcgaccagc
1081 tggacgccat atctagtttg cccacaccca gtgacatctt tgtgtcctac tctactttcc
1141 caggttttgt ttcctggagg gaccccaaga gtggctcctg gtacgttgag accctggacg
1201 acatctttga gcagtgggct cactctgaag acctgcagtc cctcctgctt agggtcgcta
1261 atgctgtttc ggtgaaaggg atttataaac agatgcctgg ttgctttaat ttcctccgga
1321 aaaaactttt ctttaaaaca tcataaggcc agggcccctc accctgcctt atcttgcacc
1381 ccaaagcttt cctgccccag gcctgaaaga ggctgaggcc tggactttcc tgcaactcaa
1441 ggactttgca gccggcacag ggtctgctct ttctctgcca gtgacagaca ggctcttagc
1501 agcttccaga ttgacgacaa gtgctgaaca gtggaggaag agggacagat gaatgccgtg
1561 gattgcacgt ggcctcttga gcagtggctg gtccagggct agtgacttgt gtcccatgat
1621 ccctgtgttg tctctagagc agggattaac ctctgcacta ctgacatgtg gggccaggtc
1681 accctttgct gtgaggctgt cctgtacatt gtgggatgtt cagcactgtc ccttgcctca
1741 atgccagtaa cgcgtcttcc tgagtggtgc caaacaaaaa ggttctcagg tgttgccaaa
1801 tatgtcctgg ggtataaaac tttcctcgcc tgacaaccac tggtctgtag ggatttttgg
1861 ctacacacaa accagtatcg ctcatagatc agcaaaccgg ggcctactag agtctgaaca
1921 gctgtaatct atgaattcta agtgaaattt taaaaattgt taatttttcc tatattgcat
1981 taattttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
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