LOCUS BC006423 2024 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aurora kinase A, mRNA (cDNA clone MGC:12769
IMAGE:3532438), complete cds.
ACCESSION BC006423
VERSION BC006423.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2024)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2024)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: e Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38327571.
FEATURES Location/Qualifiers
source 1..2024
/db_xref="H-InvDB:HIT000032825"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12769 IMAGE:3532438"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2024
/gene="AURKA"
/gene_synonym="AIK"
/gene_synonym="ARK1"
/gene_synonym="AURA"
/gene_synonym="AURORA2"
/gene_synonym="BTAK"
/gene_synonym="MGC34538"
/gene_synonym="STK7"
/db_xref="GeneID:6790"
/db_xref="HGNC:HGNC:11393"
/db_xref="MIM:603072"
CDS 26..1237
/gene="AURKA"
/gene_synonym="AIK"
/gene_synonym="ARK1"
/gene_synonym="AURA"
/gene_synonym="AURORA2"
/gene_synonym="BTAK"
/gene_synonym="MGC34538"
/gene_synonym="STK7"
/codon_start=1
/product="aurora kinase A"
/protein_id="AAH06423.1"
/db_xref="GeneID:6790"
/db_xref="HGNC:HGNC:11393"
/db_xref="MIM:603072"
/translation="MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQA
QRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPL
PSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILA
LKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV
YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG
WSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY
QETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN
CQNKESASKQS"
BASE COUNT 603 a 434 c 457 g 530 t
ORIGIN
1 cttgggtcct tgggtcgcag gcatcatgga ccgatctaaa gaaaactgca tttcaggacc
61 tgttaaggct acagctccag ttggaggtcc aaaacgtgtt ctcgtgactc agcaatttcc
121 ttgtcagaat ccattacctg taaatagtgg ccaggctcag cgggtcttgt gtccttcaaa
181 ttcttcccag cgcgttcctt tgcaagcaca aaagcttgtc tccagtcaca agccggttca
241 gaatcagaag cagaagcaat tgcaggcaac cagtgtacct catcctgtct ccaggccact
301 gaataacacc caaaagagca agcagcccct gccatcggca cctgaaaata atcctgagga
361 ggaactggca tcaaaacaga aaaatgaaga atcaaaaaag aggcagtggg ctttggaaga
421 ctttgaaatt ggtcgccctc tgggtaaagg aaagtttggt aatgtttatt tggcaagaga
481 aaagcaaagc aagtttattc tggctcttaa agtgttattt aaagctcagc tggagaaagc
541 cggagtggag catcagctca gaagagaagt agaaatacag tcccaccttc ggcatcctaa
601 tattcttaga ctgtatggtt atttccatga tgctaccaga gtctacctaa ttctggaata
661 tgcaccactt ggaacagttt atagagaact tcagaaactt tcaaagtttg atgagcagag
721 aactgctact tatataacag aattggcaaa tgccctgtct tactgtcatt cgaagagagt
781 tattcataga gacattaagc cagagaactt acttcttgga tcagctggag agcttaaaat
841 tgcagatttt gggtggtcag tacatgctcc atcttccagg aggaccactc tctgtggcac
901 cctggactac ctgccccctg aaatgattga aggtcggatg catgatgaga aggtggatct
961 ctggagcctt ggagttcttt gctatgaatt tttagttggg aagcctcctt ttgaggcaaa
1021 cacataccaa gagacctaca aaagaatatc acgggttgaa ttcacattcc ctgactttgt
1081 aacagaggga gccagggacc tcatttcaag actgttgaag cataatccca gccagaggcc
1141 aatgctcaga gaagtacttg aacacccctg gatcacagca aattcatcaa aaccatcaaa
1201 ttgccaaaac aaagaatcag ctagcaaaca gtcttaggaa tcgtgcaggg ggagaaatcc
1261 ttgagccagg gctgccatat aacctgacag gaacatgcta ctgaagttta ttttaccatt
1321 gactgctgcc ctcaatctag aacgctacac aagaaatatt tgttttactc agcaggtgtg
1381 ccttaacctc cctattcaga aagctccaca tcaataaaca tgacactctg aagtgaaagt
1441 agccacgaga attgtgctac ttatactggt tcataatctg gaggcaaggt tcgactgcag
1501 ccgccccgtc agcctgtgct aggcatggtg tcttcacagg aggcaaatcc agagcctggc
1561 tgtggggaaa gtgaccactc tgccctgacc ccgatcagtt aaggagctgt gcaataacct
1621 tcctagtacc tgagtgagtg tgtaacttat tgggttggcg aagcctggta aagctgttgg
1681 aatgagtatg tgattctttt taagtatgaa aataaagata tatgtacaga cttgtatttt
1741 ttctctggtg gcattccttt aggaatgctg tgtgtctgtc cggcaccccg gtaggcctga
1801 ttgggtttct agtcctcctt aaccacttat ctcccatatg agagtgtgaa aaataggaac
1861 acgtgctcta cctccattta gggatttgct tgggatacag aagaggccat gtgtctcaga
1921 gctgttaagg gcttattttt ttaaaacatt ggagtcatag catgtgtgta aactttaaat
1981 atgcaaataa ataagtatct atgtcaaaaa aaaaaaaaaa aaaa
//