LOCUS BC006195 4418 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ATP citrate lyase, mRNA (cDNA clone MGC:1812
IMAGE:2959339), complete cds.
ACCESSION BC006195
VERSION BC006195.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4418)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4418)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC006195.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 2 Row: k Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38569420.
FEATURES Location/Qualifiers
source 1..4418
/db_xref="H-InvDB:HIT000032659"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1812 IMAGE:2959339"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4418
/gene="ACLY"
/gene_synonym="ACL"
/gene_synonym="ATPCL"
/gene_synonym="CLATP"
/db_xref="GeneID:47"
/db_xref="HGNC:HGNC:115"
/db_xref="MIM:108728"
CDS 132..3437
/gene="ACLY"
/gene_synonym="ACL"
/gene_synonym="ATPCL"
/gene_synonym="CLATP"
/codon_start=1
/product="ATP citrate lyase"
/protein_id="AAH06195.1"
/db_xref="GeneID:47"
/db_xref="HGNC:HGNC:115"
/db_xref="MIM:108728"
/translation="MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLL
QDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFL
KNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKL
NPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLA
AKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIW
TMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTREKHPD
GKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMG
EVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAP
SRTASFSESRADEVAPAKKAKPAMPQDSVPSPRSLQGKSTTLFSRHTKAIVWGMQTRA
VQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEV
DVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPA
TVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVY
EGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPI
VCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQ
SVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAG
MPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICA
RAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMG
IGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIG
VAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPW
DDISYVLPEHMSM"
BASE COUNT 1154 a 1111 c 1142 g 1011 t
ORIGIN
1 ccgggacaaa agccggatcc cgggaagcta ccggctgctg gggtgctccg gattttgcgg
61 ggttcgtcgg gcctgtggaa gaagcgccgc gcacggactt cggcagaggt agagcaggtc
121 tctctgcagc catgtcggcc aaggcaattt cagagcagac gggcaaagaa ctcctttaca
181 agttcatctg taccacctca gccatccaga atcggttcaa gtatgctcgg gtcactcctg
241 acacagactg ggcccgcttg ctgcaggacc acccctggct gctcagccag aacttggtag
301 tcaagccaga ccagctgatc aaacgtcgtg gaaaacttgg tctcgttggg gtcaacctca
361 ctctggatgg ggtcaagtcc tggctgaagc cacggctggg acaggaagcc acagttggca
421 aggccacagg cttcctcaag aactttctga tcgagccctt cgtcccccac agtcaggctg
481 aggagttcta tgtctgcatc tatgccaccc gagaagggga ctacgtcctg ttccaccacg
541 aggggggtgt ggacgtgggt gatgtggacg ccaaggccca gaagctgctt gttggcgtgg
601 atgagaaact gaatcctgag gacatcaaaa aacacctgtt ggtccacgcc cctgaagaca
661 agaaagaaat tctggccagt tttatctccg gcctcttcaa tttctacgag gacttgtact
721 tcacctacct cgagatcaat ccccttgtag tgaccaaaga tggagtctat gtccttgact
781 tggcggccaa ggtggacgcc actgccgact acatctgcaa agtgaagtgg ggtgacatcg
841 agttccctcc ccccttcggg cgggaggcat atccagagga agcctacatt gcagacctcg
901 atgccaaaag tggggcaagc ctgaagctga ccttgctgaa ccccaaaggg aggatctgga
961 ccatggtggc cgggggtggc gcctctgtcg tgtacagcga taccatctgt gatctagggg
1021 gtgtcaacga gctggcaaac tatggggagt actcaggcgc ccccagcgag cagcagacct
1081 atgactatgc caagactatc ctctccctca tgacccgaga gaagcaccca gatggcaaga
1141 tcctcatcat tggaggcagc atcgcaaact tcaccaacgt ggctgccacg ttcaagggca
1201 tcgtgagagc aattcgagat taccagggcc ccctgaagga gcacgaagtc acaatctttg
1261 tccgaagagg tggccccaac tatcaggagg gcttacgggt gatgggagaa gtcgggaaga
1321 ccactgggat ccccatccat gtctttggca cagagactca catgacggcc attgtgggca
1381 tggccctggg ccaccggccc atccccaacc agccacccac agcggcccac actgcaaact
1441 tcctcctcaa cgccagcggg agcacatcga cgccagcccc cagcaggaca gcatcttttt
1501 ctgagtccag ggccgatgag gtggcgcctg caaagaaggc caagcctgcc atgccacaag
1561 attcagtccc aagtccaaga tccctgcaag gaaagagcac caccctcttc agccgccaca
1621 ccaaggccat tgtgtggggc atgcagaccc gggccgtgca aggcatgctg gactttgact
1681 atgtctgctc ccgagacgag ccctcagtgg ctgccatggt ctaccctttc actggggacc
1741 acaagcagaa gttttactgg gggcacaaag agatcctgat ccctgtcttc aagaacatgg
1801 ctgatgccat gaggaagcat ccggaggtag atgtgctcat caactttgcc tctctccgct
1861 ctgcctatga cagcaccatg gagaccatga actatgccca gatccggacc atcgccatca
1921 tagctgaagg catccctgag gccctcacga gaaagctgat caagaaggcg gaccagaagg
1981 gagtgaccat catcggacct gccactgttg gaggcatcaa gcctgggtgc tttaagattg
2041 gcaacacagg tgggatgctg gacaacatcc tggcctccaa actgtaccgc ccaggcagcg
2101 tggcctatgt ctcacgttcc ggaggcatgt ccaacgagct caacaatatc atctctcgga
2161 ccacggatgg cgtctatgag ggcgtggcca ttggtgggga caggtacccg ggctccacat
2221 tcatggatca tgtgttacgc tatcaggaca ctccaggagt caaaatgatt gtggttcttg
2281 gagagattgg gggcactgag gaatataaga tttgccgggg catcaaggag ggccgcctca
2341 ctaagcccat cgtctgctgg tgcatcggga cgtgtgccac catgttctcc tctgaggtcc
2401 agtttggcca tgctggagct tgtgccaacc aggcttctga aactgcagta gccaagaacc
2461 aggctttgaa ggaagcagga gtgtttgtgc cccggagctt tgatgagctt ggagagatca
2521 tccagtctgt atacgaagat ctcgtggcca atggagtcat tgtacctgcc caggaggtgc
2581 cgcccccaac cgtgcccatg gactactcct gggccaggga gcttggtttg atccgcaaac
2641 ctgcctcgtt catgaccagc atctgcgatg agcgaggaca ggagctcatc tacgcgggca
2701 tgcccatcac tgaggtcttc aaggaagaga tgggcattgg cggggtcctc ggcctcctct
2761 ggttccagaa aaggttgcct aagtactctt gccagttcat tgagatgtgt ctgatggtga
2821 cagctgatca cgggccagcc gtctctggag cccacaacac catcatttgt gcgcgagctg
2881 ggaaagacct ggtctccagc ctcacctcgg ggctgctcac catcggggat cggtttgggg
2941 gtgccttgga tgcagcagcc aagatgttca gtaaagcctt tgacagtggc attatcccca
3001 tggagtttgt gaacaagatg aagaaggaag ggaagctgat catgggcatt ggtcaccgag
3061 tgaagtcgat aaacaaccca gacatgcgag tgcagatcct caaagattac gtcaggcagc
3121 acttccctgc cactcctctg ctcgattatg cactggaagt agagaagatt accacctcga
3181 agaagccaaa tcttatcctg aatgtagatg gtctcatcgg agtcgcattt gtagacatgc
3241 ttagaaactg tgggtccttt actcgggagg aagctgatga atatattgac attggagccc
3301 tcaatggcat ctttgtgctg ggaaggagta tggggttcat tggacactat cttgatcaga
3361 agaggctgaa gcaggggctg tatcgtcatc cgtgggatga tatttcatat gttcttccgg
3421 aacacatgag catgtaacag agccaggaac cctactgcag taaactgaag acaagatctc
3481 ttcccccaag aaaaagtgta cagacagctg gcagtggagc ctgctttatt tagcaggggc
3541 ctggaatgta aacagccact ggggtacagg caccgaagac caacatccac aggctaacac
3601 cccttcagtc cacacaaaga agcttcatat tttttttata agcatagaaa taaaaaccaa
3661 gccaatattt gtgactttgc tctgctacct gctgtattta ttatatggaa gcatctaagt
3721 actgtcagga tggggtcttc ctcattgtag ggcgttagga tgttgctttc tttttccatt
3781 agttaaacat ttttttctcc tttggaggaa gggaatgaaa catttatggc ctcaagatac
3841 tatacattta aagcacccca atgtctctct tttttttttt ttacttccct ttcttcttcc
3901 ttatataaca tgaagaacat tgtattaatc tgatttttaa agatcttttt gtatgttacg
3961 tgttaagggc ttgtttggta tcccactgaa atgttctgtg ttgcagacca gagtctgttt
4021 atgtcagggg gatggggcca ttgcatcctt agccattgtc acaaaatatg tggagtagta
4081 acttaatatg taaagttgta acatacatac atttaaaatg gaaatgcaga aagctgtgaa
4141 atgtcttgtg tcttatgttc tctgtattta tgcagctgat ttgtctgtct gtaactgaag
4201 tgtgggtcca aggactccta actactttgc atctgtaatc cacaaagatt ctgggcagct
4261 gccacctcag tctcttctct gtattatcat agtctggttt aaataaacta tatagtaaca
4321 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4381 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//