LOCUS BC006085 3491 bp mRNA linear HUM 06-APR-2004
DEFINITION Homo sapiens ADP-ribosylation factor GTPase activating protein 1,
mRNA (cDNA clone MGC:12592 IMAGE:3628606), complete cds.
ACCESSION BC006085
VERSION BC006085.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3491)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3491)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: i Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 28416434.
FEATURES Location/Qualifiers
source 1..3491
/db_xref="H-InvDB:HIT000258911"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12592 IMAGE:3628606"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3491
/gene="ARFGAP1"
/gene_synonym="ARF1GAP"
/gene_synonym="HRIHFB2281"
/gene_synonym="MGC39924"
/db_xref="GeneID:55738"
/db_xref="MIM:608377"
CDS 92..1303
/gene="ARFGAP1"
/gene_synonym="ARF1GAP"
/gene_synonym="HRIHFB2281"
/gene_synonym="MGC39924"
/codon_start=1
/product="ARFGAP1 protein"
/protein_id="AAH06085.1"
/db_xref="GeneID:55738"
/db_xref="MIM:608377"
/translation="MASPRTRKVLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLE
CSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEK
YNSRAAALFRDKVVALAEGREWSLESSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASS
DKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFLNNAMSSLYSGWSSFTTGA
SRFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGKIFDDVSSGVSQLA
SKCQRRLCCHQSHCSAGHLGRAFCPVSWHEALCGQTGREEQASLLPPKHVVGALEVCA
RGCPRCHVPHTPGTAAEWPGRLCLSRESVVRDGGTSPPFFRGKQRAPWTAPRRATVIR
TAVWTTSKTAT"
misc_feature 110..463
/gene="ARFGAP1"
/gene_synonym="ARF1GAP"
/gene_synonym="HRIHFB2281"
/gene_synonym="MGC39924"
/note="ArfGap; Region: Putative GTPase activating protein
for Arf. Putative zinc fingers with GTPase activating
proteins (GAPs) towards the small GTPase, Arf. The GAP of
ARD1 stimulates GTPase hydrolysis for ARD1 but not ARFs"
/db_xref="CDD:pfam01412"
BASE COUNT 652 a 1041 c 1122 g 676 t
ORIGIN
1 ggcgaccggg cgcatcctca ttgcagtgcg gcggccctac ctcggccctg gcctgacccc
61 ggcggccctg cccgcccctc cctccagcat catggccagc ccaagaacca ggaaggttct
121 taaagaagtc agggtgcagg atgagaacaa cgtttgtttt gagtgtggcg cgttcaatcc
181 tcagtgggtc agtgtgacct acggcatctg gatctgcctg gagtgctcgg ggagacaccg
241 cgggcttggg gttcacctca gctttgtgcg ctctgttact atggacaagt ggaaggacat
301 tgagcttgag aagatgaaag ctggtgggaa tgctaagttc cgagagttcc tggagtctca
361 ggaggattac gatccttgct ggtccttgca ggagaagtac aacagcagag ccgcggccct
421 ctttagggat aaggtggtcg ctctggccga aggcagagag tggtctctgg agtcatcacc
481 tgcccagaac tggaccccac ctcagcccag gacgctgccg tccatggtgc accgagtctc
541 tggccagccg cagagtgtga ccgcctcctc ggacaaggct tttgaagact ggctgaatga
601 tgacctcggc tcctatcaag gggcccaggg gaatcgctac gtggggtttg ggaacacgcc
661 accgcctcag aagaaagaag atgacttcct caacaacgcc atgtcctccc tgtactcggg
721 ctggagcagc ttcaccactg gagccagccg gtttgcctcg gcagccaagg agggcgctac
781 aaagtttgga tcccaagcga gtcagaaggc gtccgagctg ggccacagcc tgaacgagaa
841 cgtcctcaag cctgcgcagg agaaggtgaa ggagggaaag atttttgatg atgtctccag
901 tggggtctct cagttggcgt ccaagtgcca gcgccgtctt tgctgccatc agtcccactg
961 ctctgcgggc catttggggc gtgcattttg tcctgtttcc tggcatgagg cgctctgcgg
1021 acagacgggg agggaagagc aggcctcgct cctccccccc aagcatgtgg tgggagctct
1081 tgaggtctgt gcacgaggct gtcctcgctg ccatgtcccg cacacacctg gcaccgctgc
1141 agagtggccg gggcgtctgt gtctgtccag ggagtcggta gtaagggatg gcgggacgtc
1201 accacctttt tttcggggaa agcagagggc cccttggaca gcccctcgga gggccacagt
1261 tatcagaaca gcggtctgga ccacttccaa aacagcaaca tagaccagag cttctgggag
1321 acctttggaa gtgctgagcc caccaagacc cgcaagtccc cgagcagcga cagctggacg
1381 tgcgcggaca cctccaccga gaggaggagc tcggacagct gggaggtgtg gggctcggcc
1441 tccaccaaca ggaacagcaa cagcgacggc ggggagggcg gggagggcac caagaaggca
1501 gtgccgccgg ccgtgcccac tgatgatggc tgggacaacc agaactggta gggcccactg
1561 cgcccccgtc cccagcgccc ccgggcgact tcgtgtttgc actctgccct cgtcgttcct
1621 cctccttcca tttgacccaa gaatcagcaa ctgcagtgtg aggacagcgt ctcgggaggc
1681 aggaccctag ggagacccgg gtgtgcgccg cctgcgcgtg gggagtcttc ggtgcgtggg
1741 ggcggcttgc tgtccagcct gtgtgggggc cgtcccgtcc cacactcccc tgggcattct
1801 tggactcaag gccggggctc tgcgtggctt gctgggaggt gggctgcagc acagaggcct
1861 gtgactgcgt tccagcggcc agttcactac gcagtatctc tggggcctgg gaccagccac
1921 gtgccgagct gtcagcgacg tgaggtgtcc cttctcgttg agatatttaa ctttggtttt
1981 gctctagttc tttctttttg aagagagtga ctggagtggt aaagatggaa atgctggaaa
2041 tgatactggc gctcacgctg ccatccgacc accctcggct cccgagtcca cgcctgcctg
2101 ggcctgtgct gtcagacccg cgtcggtcgt aaccctctgt ggctcccctg catcagcacc
2161 gtcccaccac caagttcacc aggttcacca gacacggcct ccacaatagc cacacccaca
2221 cctgagctgt tctcagtgct ggaacttgac catcctggaa caccctggaa gaaaaaggag
2281 cgcagggtgg gccctcggcc ctgatgcagg agggtgcgat agcggacgtg gccaggcagg
2341 aggggccggg ttcaggagct gagcagggga tgcctgtgcg tggtgcctgg gtctagggaa
2401 gctccagccc caggatgggg ctgccctgca caccggtgcc cgccacatgc caaccctcac
2461 ctccccgagg actggatgat gtgctgccac gtgtgactcg tctcccttgt ctgccctgtg
2521 tgaccctcag tcttggccag ccatgcatgc gcccgaagct cgtgcagttt gtacgtgagg
2581 tgctctcctc cctgccacca tgctcatcac tctggccttg gccatgctcc ctggtcaccc
2641 cacttcccgg tcgccgtctg cagcactcct ggagcagcct gggcccttca gcccctgtgc
2701 tcgtcccacc ctagggactc agccacttgc agaacaggat gggaccgaga tttcagcgag
2761 ccctcctggc gcccggtcct ccctgtgggc accagccctc ttggtagctg gtgtggaggg
2821 ccggtgtcct tggctgccac ggagggattt gatcaccgaa gcagccacct gctgtagttg
2881 gacctgaggt cagaggcggg gcatcagagg ctcaaggtgc tgagaagcca ccgggaaagc
2941 agccagcaca aagggcccag gaagccagcc cccgagagct gagcgtgggg gtctttgagt
3001 gtctttctcc aagctgagac gtgggcggcc gcgtggtatc tcccgagggc tgcttggacc
3061 ctggtgggct gagtgctccg aggaggggtg gactccacct tggacagtgg gatgtggtgt
3121 tccacatgtg cctgtttcca cgccagcacc ttgacttggc agcatggagc caaggtctgt
3181 ccccgcccag gagggtgcct tcctcggggg tagggggacg gcccactctg ccccagggag
3241 tcccttttga tgggaagtgc agtcagcagc gtggaggtgt ctgggccacc ttcagaaggt
3301 ggatgtggtg gccgagaccc cgtccacgga gggtgatggc ctttcccttc tgcaggtgcg
3361 ggcaggtggg cctgggaccg gtgctggggc ctctccttgc tgtgtgtgag ggcccaggtg
3421 gaaggcgcgg acctgacagc attccaataa agcatacggg aacatgaaaa aaaaaaaaaa
3481 aaaaaaaaaa a
//