LOCUS BC006083 2504 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens tyrosyl-DNA phosphodiesterase 1, mRNA (cDNA clone
IMAGE:2961386), complete cds.
ACCESSION BC006083
VERSION BC006083.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2504)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2504)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 18 Row: b Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20127585
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..2504
/db_xref="H-InvDB:HIT000032592"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:2961386"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2504
/gene="TDP1"
/gene_synonym="FLJ11090"
/gene_synonym="SCAN1"
/db_xref="GeneID:55775"
/db_xref="MIM:607198"
CDS 244..1140
/gene="TDP1"
/gene_synonym="FLJ11090"
/gene_synonym="SCAN1"
/codon_start=1
/product="TDP1 protein"
/protein_id="AAH06083.1"
/db_xref="GeneID:55775"
/db_xref="MIM:607198"
/translation="MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEP
RYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQ
KQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDK
GNPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPE
FRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLR
VVIHTSNLIHADWHQKTQGTHL"
BASE COUNT 714 a 590 c 591 g 609 t
ORIGIN
1 ccattctccg cagagttgga gcacacagct gtattaaaaa ggcaaatcga aggccgggcg
61 cggtgactca cgcctgtcat cctagcactt tgggaggccg aggcggctga atcacttgag
121 gttaggagtt tgagatcagc ccgggcaaca tggtgaaacc ccgtctctac aaaaatagaa
181 aaattagccg agcgtgatgg tggatgcctg taatcctagc tcttcgggag gctaaggagt
241 ataatgtctc aggaaggcga ttatgggagg tggaccatat ctagtagtga tgaaagtgag
301 gaagaaaagc caaaaccaga caagccatct acctcttctc ttctctgtgc caggcaagga
361 gcagcaaatg agcccaggta cacctgttcc gaggcccaga aagctgcaca caagaggaaa
421 atatcacctg tgaaattcag caatacagat tcagttttac ctcccaaaag gcagaaaagc
481 ggttcccagg aggacctcgg ctggtgtctg tccagcagtg atgatgagct gcaaccagaa
541 atgccgcaga agcaggctga gaaagtggtg atcaaaaagg agaaagacat ctctgctccc
601 aatgacggca ctgcccaaag aactgaaaat catggcgctc ccgcctgcca caggctcaaa
661 gaggaggaag acgagtatga gacatcaggg gagggccagg acatttggga catgctggat
721 aaagggaacc ccttccagtt ttacctcact agagtctctg gagttaagcc aaagtataac
781 tctggagccc tccacatcaa ggatatttta tctcctttat ttgggacgct tgtttcttca
841 gctcagttta actactgctt tgacgtggac tggctcgtaa aacagtatcc accagagttc
901 aggaagaagc caatcctgct tgtgcatggt gataagcgag aggctaaggc tcacctccat
961 gcccaggcca agccttacga gaacatctct ctctgccagg caaagttgga tattgcgttt
1021 ggaacacacc acacgaaaat gatgctgctg ctctatgaag aaggcctccg ggttgtcata
1081 cacacctcca acctcatcca tgctgactgg caccagaaaa ctcaaggaac tcacctgtga
1141 gtgaatctct gatccaggag gagcctcact cagcctggga actttgaggt gctattgcaa
1201 ggggaggtcc tccacgtctg tccagcccaa cctggtcatt ttacacacgg aggcaaaggc
1261 ccagagagat cacagagctt acccaaaatg aatatggttg agccccttat acccacgaat
1321 tgctgatgga acccacaaat ctggagagtc gccaacacat tttaaagctg atctcatcag
1381 ttacttgatg gcttataatg ccccttctct caaggagtgg atagatgtca ttcacaagca
1441 cgatctctct gaaacaaatg tttatcttat tggttcaacc ccaggacgct ttcaaggaag
1501 tcaaaaagat aattggggac attttagact taagaagctt tgcataatta tcaaagcagg
1561 aaatgcagat cagtcttctg cagtgtttta gctgcttctg aaagaccatg cctcatccat
1621 gcctaacgca gagtcctggc ctgtcgtagg tcagttttca agcgttggct ccttgggagc
1681 cgatgaatca aagtggttat gttctgagtt taaagagagc atgctgacac tggggaagga
1741 aagcaagact ccaggaaaaa gctctgttcc tctttacttg atctatcctt ctgtggaaaa
1801 tgtgcggacc agtttagaag gatatcctgc tgggggctct cttccctata gcatccagac
1861 agctgaaaaa cagaattggc tgcattccta ttttcacaaa tggtcagctg agacttctgg
1921 ccgcagcaat gccatgccac atattaagac atatatgagg ccttctccag acttcagtaa
1981 aattgcttgg ttccttgtca caagcgcaaa tctgtccaag gctgcctggg gagcattgga
2041 gaagaatggc acccagctga tgatccgctc ctacgagctc ggggtccttt tcctcccttc
2101 agcatttggt ctagacagtt tcaaagtgaa acagaagttc ttcgctggca gccaggagcc
2161 aatggccacc tttcctgtgc catatgattt gcctccagaa ctgtatggaa gtaaagatcg
2221 gccatggata tggaacattc cttatgtcaa agcaccggat acgcatggga acatgtgggt
2281 gccctcctga gaatcttgag gcactgtgaa atttaagtgt aagacattga gccacaaaca
2341 tggaatctct tctttgtact ggatgtccac ttcccttaaa gtcttatttg cacccttaca
2401 aaatctttcc aaaggtcact cttatgaatg gatgttggtt atacttttaa tggacattaa
2461 cattcctaat aaagtattag tttcttaaaa aaaaaaaaaa aaaa
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