LOCUS BC005825 1227 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens pyridoxal (pyridoxine, vitamin B6) kinase, mRNA (cDNA
clone MGC:1687 IMAGE:2989843), complete cds.
ACCESSION BC005825
VERSION BC005825.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1227)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1227)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC005825.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 3 Row: i Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18644884.
FEATURES Location/Qualifiers
source 1..1227
/db_xref="H-InvDB:HIT000032460"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1687 IMAGE:2989843"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_9"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1227
/gene="PDXK"
/gene_synonym="PKH"
/gene_synonym="PNK"
/db_xref="GeneID:8566"
/db_xref="MIM:179020"
CDS 199..1053
/gene="PDXK"
/gene_synonym="PKH"
/gene_synonym="PNK"
/codon_start=1
/product="PDXK protein"
/protein_id="AAH05825.1"
/db_xref="GeneID:8566"
/db_xref="MIM:179020"
/translation="MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFS
NHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTVCDPVLGDKWDGEGSMYVPE
DLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSS
DLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTH
KHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPE
IVVQATVL"
misc_feature 214..1050
/gene="PDXK"
/gene_synonym="PKH"
/gene_synonym="PNK"
/note="PdxK; Region: Pyridoxal/pyridoxine/pyridoxamine
kinase [Coenzyme metabolism]"
/db_xref="CDD:COG2240"
BASE COUNT 299 a 343 c 377 g 208 t
ORIGIN
1 cggaactcgc gggttcggag ccgcccgctg aggtcagaag gaggcgtctg cgctgatcgg
61 gtccgccgcg cgccagagcc agagtcgcag ccgaggggag ccggggccgg agcccgagcc
121 cgagccgagc cggagcccga gcgagcggcg gagaccgtgc ccccgcctcg gccccgcgcc
181 gccgcggcca ggcccggcat ggaggaggag tgccgggtgc tctccataca gagccacgtc
241 atccgcggct acgtgggcaa ccgggcggcc acgttcccgc tgcaggtttt gggatttgag
301 attgacgcgg tgaactctgt ccagttttca aaccacacag gctatgccca ctggaagggc
361 caagtgctga attcagatga gctccaggag ttgtacgaag gcctgaggct gaacaacatg
421 aataaatatg actacgtgct cacagtgtgt gatccagtct tgggtgacaa gtgggacggc
481 gaaggctcga tgtacgtccc ggaggacctc cttcccgtct acaaagaaaa agtggtgccg
541 cttgcagaca ttatcacgcc caaccagttt gaggccgagt tactgagtgg ccggaagatc
601 cacagccagg aggaagcctt gcgggtgatg gacatgctgc actctatggg ccccgacacc
661 gtggtcatca ccagctccga cctgccctcc ccgcagggca gcaactacct gattgtgctg
721 gggagtcaga ggaggaggaa tcccgctggc tccgtggtga tggaacgcat ccggatggac
781 attcgcaaag tggacgccgt ctttgtgggc actggggacc tgtttgctgc catgctcctg
841 gcgtggacac acaagcaccc caataacctc aaggtggcct gtgagaagac cgtgtctacc
901 ttgcaccacg ttctgcagag gaccatccag tgtgcaaaag cccaggccgg ggaaggagtg
961 aggcccagcc ccatgcagct ggagctgcgg atggtgcaga gcaaaaggga catcgaggac
1021 ccagagatcg tcgtccaggc cacggtgctg tgagggcccc gccgctcgcc cgtgacacgc
1081 agcgcgttgg tgtctccgtg tttgtccctg tgaaaacatg taacgtctgc cttagagcca
1141 tgaccgaaac ttgatatttt tttctttaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1201 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//