LOCUS BC005395 1621 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens hemopexin, mRNA (cDNA clone MGC:12533 IMAGE:4071616),
complete cds.
ACCESSION BC005395
VERSION BC005395.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1621)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1621)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (27-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 16 Row: h Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11321560.
FEATURES Location/Qualifiers
source 1..1621
/db_xref="H-InvDB:HIT000032438"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12533 IMAGE:4071616"
/tissue_type="Liver"
/clone_lib="NIH_MGC_76"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1621
/gene="HPX"
/db_xref="GeneID:3263"
/db_xref="MIM:142290"
CDS 62..826
/gene="HPX"
/codon_start=1
/product="HPX protein"
/protein_id="AAH05395.1"
/db_xref="GeneID:3263"
/db_xref="MIM:142290"
/translation="MARVLGAPVALGLWSLCWSLAIATPLPPTSAHGNVAEGETKPDP
DVTERCSDGWSFDATTLDDNGTMLFFKGEFVWKSHKWDRELISERWKNFPSPVDAAFR
QGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAEGVL
FFQGDREWFWDLATGTMKERSWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGEVPP
RYPRDVRDYFMPCPGRGHGHRNGTGHGNSICAVAHI"
misc_feature 227..346
/gene="HPX"
/note="HX; Region: Hemopexin-like repeats. Hemopexin is a
heme-binding protein that transports heme to the liver.
Hemopexin-like repeats occur in vitronectin and some
matrix metalloproteinases family (matrixins). The HX
repeats of some matrixins bind tissue inhibitor of
metalloproteinases (TIMPs)"
/db_xref="CDD:smart00120"
misc_feature 647..754
/gene="HPX"
/note="hemopexin; Region: Hemopexin. Hemopexin is a
heme-binding protein that transports heme to the liver.
Hemopexin-like repeats occur in vitronectin and some
matrix metallopeptidases family (matrixins). The HX
repeats of some matrixins bind tissue inhibitor of
metallopeptidases (TIMPs)"
/db_xref="CDD:pfam00045"
BASE COUNT 370 a 438 c 441 g 372 t
ORIGIN
1 aactctatat agggagttca actggtcacc cagagctgtc ctgtggcctc tgcagctcag
61 catggctagg gtactgggag cacccgttgc actggggttg tggagcctat gctggtctct
121 ggccattgcc acccctcttc ctccgactag tgcccatggg aatgttgctg aaggcgagac
181 caagccagac ccagacgtga ctgaacgctg ctcagatggc tggagctttg atgctaccac
241 cctggatgac aatggaacca tgctgttttt taaaggggag tttgtgtgga agagtcacaa
301 atgggaccgg gagttaatct cagagagatg gaagaatttc cccagccctg tggatgctgc
361 attccgtcaa ggtcacaaca gtgtctttct gatcaagggg gacaaagtct gggtataccc
421 tcctgaaaag aaggagaaag gatacccaaa gttgctccaa gatgaatttc ctggaatccc
481 atccccactg gatgcagctg tggaatgtca ccgtggagaa tgtcaagctg aaggcgtcct
541 cttcttccaa ggtgaccgcg agtggttctg ggacttggct acgggaacca tgaaggagcg
601 ttcctggcca gctgttggga actgctcctc tgccctgaga tggctgggcc gctactactg
661 cttccagggt aaccaattcc tgcgcttcga ccctgtcagg ggagaggtgc ctcccaggta
721 cccgcgggat gtccgagact acttcatgcc ctgccctggc agaggccatg gacacaggaa
781 tgggactggc catgggaaca gtatatgcgc tgtagcccac atctagtctt gtctgcactg
841 acgtctgaca accatggtgc cacctatgcc ttcagtggga cccactactg gcgtctggac
901 accagccggg atggctggca tagctggccc attgctcatc agtggcccca gggtccttca
961 gcagtggatg ctgccttttc ctgggaagaa aaactctatc tggtccaggg cacccaggta
1021 tatgtcttcc tgacaaaggg aggctatacc ctagtaagcg gttatccgaa gcggctggag
1081 aaggaagtcg ggacccctca tgggattatc ctggactctg tggatgcggc ctttatctgc
1141 cctgggtctt ctcggctcca tatcatggca ggacggcggc tgtggtggct ggacctgaag
1201 tcaggagccc aagccacgtg gacagagctt ccttggcccc atgagaaggt agacggagcc
1261 ttgtgtatgg aaaagtccct tggccctaac tcatgttccg ccaatggtcc cggcttgtac
1321 ctcatccatg gtcccaattt gtactgctac agtgatgtgg agaaactgaa tgcagccaag
1381 gcccttccgc aaccccagaa tgtgaccagt ctcctgggct gcactcactg aggggccttc
1441 tgacatgagt ctggcctggc cccacctcct agttcctcat aataaagaca gattgcttct
1501 tcgcttctca ctgaggggcc ttctgacatg agtctggcct ggccccacct ccccagtttc
1561 tcataataaa gacagattgc ttcttcactt caaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1621 a
//