LOCUS BC005394 1195 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldo-keto reductase family 1, member A1 (aldehyde
reductase), mRNA (cDNA clone MGC:12529 IMAGE:4051944), complete
cds.
ACCESSION BC005394
VERSION BC005394.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1195)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1195)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 16 Row: b Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24497576.
FEATURES Location/Qualifiers
source 1..1195
/db_xref="H-InvDB:HIT000032437"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12529 IMAGE:4051944"
/tissue_type="Kidney, hypernephroma"
/clone_lib="NIH_MGC_58"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1195
/gene="AKR1A1"
/gene_synonym="ALDR1"
/gene_synonym="ALR"
/gene_synonym="MGC12529"
/gene_synonym="MGC1380"
/db_xref="GeneID:10327"
/db_xref="HGNC:HGNC:380"
/db_xref="MIM:103830"
CDS 96..1073
/gene="AKR1A1"
/gene_synonym="ALDR1"
/gene_synonym="ALR"
/gene_synonym="MGC12529"
/gene_synonym="MGC1380"
/codon_start=1
/product="aldo-keto reductase family 1, member A1
(aldehyde reductase)"
/protein_id="AAH05394.1"
/db_xref="GeneID:10327"
/db_xref="HGNC:HGNC:380"
/db_xref="MIM:103830"
/translation="MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHI
DCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADL
QLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALG
LSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDR
AWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKV
FDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY"
BASE COUNT 295 a 304 c 333 g 263 t
ORIGIN
1 acttaagctg aggatcgttg gatctctggc ggggtgcaga actgagccca ggccacagta
61 ccctattcac gctctgtgct tgtgccaagg gggcaatggc ggcttcctgt gttctactgc
121 acactgggca gaagatgcct ctgattggtc tgggtacctg gaagagtgag cctggtcagg
181 taaaagcagc tgttaagtat gcccttagcg taggctaccg ccacattgat tgtgctgcta
241 tctacggcaa tgagcctgag attggggagg ccctgaagga ggacgtggga ccaggcaagg
301 cggtgcctcg ggaggagctg tttgtgacat ccaagctgtg gaacaccaag caccaccccg
361 aggatgtgga gcctgccctc cggaagactc tggctgacct ccagctggag tatctggacc
421 tgtacctgat gcactggcct tatgcctttg agcggggaga caaccccttc cccaagaatg
481 ctgatgggac tatatgctac gactccaccc actacaagga gacttggaag gctctggagg
541 cactggtggc taaggggctg gtgcaggcgc tgggcctgtc caacttcaac agtcggcaga
601 ttgatgacat actcagtgtg gcctccgtgc gtccagctgt cttgcaggtg gagtgccacc
661 catacttggc tcaaaatgag ctaattgccc actgccaagc acgtggcctg gaggtaactg
721 cttatagccc tttgggctcc tctgatcgtg catggcgtga tcctgatgag cctgtcctgc
781 tggaggaacc agtagtcctg gcattggctg aaaagtatgg ccgatctcca gctcagatct
841 tgctcaggtg gcaggtccag cggaaagtga tctgcatccc caaaagtatc actccttctc
901 gaatccttca gaacatcaag gtgtttgact tcacctttag cccagaagag atgaagcagc
961 taaatgccct gaacaaaaat tggagatata ttgtgcctat gcttacggtg gatgggaaga
1021 gagtcccaag ggatgcaggg catcctctgt acccctttaa tgacccgtac tgagaccaca
1081 gcttcttggc ctcccttcca gctctgcagc taatgaggtc ctgccacaac ggaaagaggg
1141 agttaataaa gccattggag caccaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//