LOCUS BC005218 1903 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens methionine adenosyltransferase II, beta, mRNA (cDNA
clone MGC:12237 IMAGE:3931953), complete cds.
ACCESSION BC005218
VERSION BC005218.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1903)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1903)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 16 Row: h Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33519454.
FEATURES Location/Qualifiers
source 1..1903
/db_xref="H-InvDB:HIT000032297"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12237 IMAGE:3931953"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_62"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1903
/gene="MAT2B"
/gene_synonym="MAT-II"
/gene_synonym="MATIIbeta"
/gene_synonym="MGC12237"
/gene_synonym="Nbla02999"
/gene_synonym="TGR"
/db_xref="GeneID:27430"
/db_xref="HGNC:HGNC:6905"
/db_xref="MIM:605527"
CDS 113..1084
/gene="MAT2B"
/gene_synonym="MAT-II"
/gene_synonym="MATIIbeta"
/gene_synonym="MGC12237"
/gene_synonym="Nbla02999"
/gene_synonym="TGR"
/codon_start=1
/product="methionine adenosyltransferase II, beta"
/protein_id="AAH05218.1"
/db_xref="GeneID:27430"
/db_xref="HGNC:HGNC:6905"
/db_xref="MIM:605527"
/translation="MPEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHA
VGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLN
VDASGNLAKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVL
ENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVAT
VCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGA
QRPRNTQLDCSKLETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH"
BASE COUNT 575 a 334 c 408 g 586 t
ORIGIN
1 acgttttggc gtgcctgcgc tctctgcagg cagaagcgaa caaagaccca gcaagagaag
61 gcagaggcta agacccatcc cgtatctgct ctcctgaaat aattctggag tcatgcctga
121 aatgccagag gacatggagc aggaggaagt taacatccct aataggaggg ttctggttac
181 tggtgccact gggcttcttg gcagagctgt acacaaagaa tttcagcaga ataattggca
241 tgcagttggc tgtggtttca gaagagcaag accaaaattt gaacaggtta atctgttgga
301 ttctaatgca gttcatcaca tcattcatga ttttcagccc catgttatag tacattgtgc
361 agcagagaga agaccagatg ttgtagaaaa tcagccagat gctgcctctc aacttaatgt
421 ggatgcttct gggaatttag caaaggaagc agctgctgtt ggagcatttc tcatctacat
481 tagctcagat tatgtatttg atggaacaaa tccaccttac agagaggaag acataccagc
541 tcccctaaat ttgtatggca aaacaaaatt agatggagaa aaggctgtcc tggagaacaa
601 tctaggagct gctgttttga ggattcctat tctgtatggg gaagttgaaa agctcgaaga
661 aagtgctgtg actgttatgt ttgataaagt gcagttcagc aacaagtcag caaacatgga
721 tcactggcag cagaggttcc ccacacatgt caaagatgtg gccactgtgt gccggcagct
781 agcagagaag agaatgctgg atccatcaat taagggaacc tttcactggt ctggcaatga
841 acagatgact aagtatgaaa tggcatgtgc aattgcagat gccttcaacc tccccagcag
901 tcacttaaga cctattactg acagccctgt cctaggagca caacgtccga gaaatactca
961 gcttgactgc tccaaattgg agaccttggg cattggccaa cgaacaccat ttcgaattgg
1021 aatcaaagaa tcactttggc ctttcctcat tgacaagaga tggagacaaa cggtctttca
1081 ttagtttatt tgtgttgggt tctttttttt ttttttaaat gaaaagtata gtatgtggca
1141 ctttttaaag aacaaaggaa atagttttgt atgagtactt taattgtgac tcttaggatc
1201 tttcaggtaa atgatgctct tgcactagtg aaattgtcta aagaaactaa agggcagtca
1261 tgccctgttt gcagtaattt ttctttttat cattttgttt gtcctggcta aacttggagt
1321 ttgagtatag taaattatga tccttaaata tttgagagtc aggatgaagc agatctgctg
1381 tagacttttc agatgaaatt gttcattctc gtaacctcca tattttcagg atttttgaag
1441 ctgttgacct tttcatgttg attattttaa attgtgtgaa atagtataaa aatcattggt
1501 gttcattatt tgctttgcct gagctcagat caaaatgttt gaagaaagga actttatttt
1561 tgcaagttac gtacagtttt tatgcttgag atatttcaac atgttatgta tattggaact
1621 tctacagctt gatgcctcct gcttttatag cagtttatgg ggagcacttg aaagagcgtg
1681 tgtacatgta ttttttttct aggcaaacat tgaatgcaaa cgtgtatttt tttaatataa
1741 atatataact gtccttttca tcccatgttg ccgctaagtg atatttcata tgtgtggtta
1801 tactcataat aatgggcctt gtaagtcttt tcaccattca tgaataataa taaatatgta
1861 ctgctggcat gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
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