LOCUS BC004928 2567 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B
member 1, mRNA (cDNA clone MGC:10493 IMAGE:3621040), complete cds.
ACCESSION BC004928
VERSION BC004928.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2567)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2567)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 13 Row: h Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, Similarity but not identity to protein.
FEATURES Location/Qualifiers
source 1..2567
/db_xref="H-InvDB:HIT000032091"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10493 IMAGE:3621040"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2567
/gene="HSP90AB1"
/gene_synonym="D6S182"
/gene_synonym="HSP90-BETA"
/gene_synonym="HSP90B"
/db_xref="GeneID:3326"
/db_xref="HGNC:HGNC:5258"
/db_xref="MIM:140572"
CDS 85..2259
/gene="HSP90AB1"
/gene_synonym="D6S182"
/gene_synonym="HSP90-BETA"
/gene_synonym="HSP90B"
/codon_start=1
/product="heat shock protein 90kDa alpha (cytosolic),
class B member 1"
/protein_id="AAH04928.1"
/db_xref="GeneID:3326"
/db_xref="HGNC:HGNC:5258"
/db_xref="MIM:140572"
/translation="MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELI
SNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNL
GTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESS
AGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE
KEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKY
IDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF
IPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISR
EMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRR
LSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGF
EVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKL
MKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKK
HLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR
MIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD"
BASE COUNT 745 a 547 c 652 g 623 t
ORIGIN
1 ctccggcgca gtgttgggac tgtctgggta tcggaaagca agcctacgtt gctcactatt
61 acgtataatc cttttctttt caagatgcct gaggaagtgc accatggaga ggaggaggtg
121 gagacttttg cctttcaggc agaaattgcc caactcatgt ccctcatcat caataccttc
181 tattccaaca aggagatttt ccttcgggag ttgatctcta atgcttctga tgccttggac
241 aagattcgct atgagagcct gacagaccct tcgaagttgg acagtggtaa agagctgaaa
301 attgacatca tccccaaccc tcaggaacgt accctgactt tggtagacac aggcattggc
361 atgaccaaag ctgatctcat aaataatttg ggaaccattg ccaagtctgg tactaaagca
421 ttcatggagg ctcttcaggc tggtgcagac atctccatga ttgggcagtt tggtgttggc
481 ttttattctg cctacttggt ggcagagaaa gtggttgtga tcacaaagca caacgatgat
541 gaacagtatg cttgggagtc ttctgctgga ggttccttca ctgtgcgtgc tgaccatggt
601 gagcccattg gcaggggtac caaagtgatc ctccatctta aagaagatca gacagagtac
661 ctagaagaga ggcgggtcaa agaagtagtg aagaagcatt ctcagttcat aggctatccc
721 atcacccttt atttggagaa ggaacgagag aaggaaatta gtgatgatga ggcagaggaa
781 gagaaaggtg agaaagaaga ggaagataaa gatgatgaag aaaaacccaa gatcgaagat
841 gtgggttcag atgaggagga tgacagcggt aaggataaga agaagaaaac taagaagatc
901 aaagagaaat acattgatca ggaagaacta aacaagacca agcctatttg gaccagaaac
961 cctgatgaca tcacccaaga ggagtatgga gaattctaca agagcctcac taatgactgg
1021 gaagaccact tggcagtcaa gcacttttct gtagaaggtc agttggaatt cagggcattg
1081 ctatttattc ctcgtcgggc tccctttgac ctttttgaga acaagaagaa aaagaacaac
1141 atcaaactct atgtccgccg tgtgttcatc atggacagct gtgatgagtt gataccagag
1201 tatctcaatt ttatccgtgg tgtggttgac tctgaggatc tgcccctgaa catctcccga
1261 gaaatgctcc agcagagcaa aatcttgaaa gtcattcgca aaaacattgt taagaagtgc
1321 cttgagctct tctctgagct ggcagaagac aaggagaatt acaagaaatt ctatgaggca
1381 ttctctaaaa atctcaagct tggaatccac gaagactcca ctaaccgccg ccgcctgtct
1441 gagctgctgc gctatcatac ctcccagtct ggagatgaga tgacatctct gtcagagtat
1501 gtttctcgca tgaaggagac acagaagtcc atctattaca tcactggtga gagcaaagag
1561 caggtggcca actcagcttt tgtggagcga gtgcggaaac ggggcttcga ggtggtatat
1621 atgaccgagc ccattgacga gtactgtgtg cagcagctca aggaatttga tgggaagagc
1681 ctggtctcag ttaccaagga gggtctggag ctgcctgagg atgaggagga gaagaagaag
1741 atggaagaga gcaaggcaaa gtttgagaac ctctgcaagc tcatgaaaga aatcttagat
1801 aagaaggttg agaaggtgac aatctccaat agacttgtgt cttcaccttg ctgcattgtg
1861 accagcacct acggctggac agccaatatg gagcggatca tgaaagccca ggcacttcgg
1921 gacaactcca ccatgggcta tatgatggcc aaaaagcacc tggagatcaa ccctgaccac
1981 cccattgtgg agacgctgcg gcagaaggct gaggccgaca agaatgataa ggcagttaag
2041 gacctggtgg tgctgctgtt tgaaaccgcc ctgctatctt ctggcttttc ccttgaggat
2101 ccccagaccc actccaaccg catctatcgc atgatcaagc taggtctagg tattgatgaa
2161 gatgaagtgg cagcagagga acccaatgct gcagttcctg atgagatccc ccctctcgag
2221 ggcgatgagg atgcgtctcg catggaagaa gtcgattagg ttaggagttc atagttggaa
2281 aacttgtgcc cttgtatagt gtccccatgg gctcccactg cagcctcgag tgcccctgtc
2341 ccacctggct ccccctgctg gtgtctagtg tttttttccc tctcctgtcc ttgtgttgaa
2401 ggcagtaaac taagggtgtc aagccccatt ccctctctac tcttgacagc aggattggat
2461 gttgtgtatt gtggtttatt ttattttctt cattttgttc tgaaattaaa gtatgcaaaa
2521 taaagaatat gccgttttaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//