LOCUS BC004553 1889 bp mRNA linear HUM 19-JUN-2006
DEFINITION Homo sapiens receptor-interacting serine-threonine kinase 2, mRNA
(cDNA clone MGC:10684 IMAGE:4026156), complete cds.
ACCESSION BC004553
VERSION BC004553.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1889)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1889)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC004553.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 15 Row: n Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40255024.
FEATURES Location/Qualifiers
source 1..1889
/db_xref="H-InvDB:HIT000032020"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10684 IMAGE:4026156"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1889
/gene="RIPK2"
/gene_synonym="CARD3"
/gene_synonym="CARDIAK"
/gene_synonym="CCK"
/gene_synonym="GIG30"
/gene_synonym="RICK"
/gene_synonym="RIP2"
/db_xref="GeneID:8767"
/db_xref="HGNC:HGNC:10020"
/db_xref="MIM:603455"
CDS 203..1825
/gene="RIPK2"
/gene_synonym="CARD3"
/gene_synonym="CARDIAK"
/gene_synonym="CCK"
/gene_synonym="GIG30"
/gene_synonym="RICK"
/gene_synonym="RIP2"
/codon_start=1
/product="receptor-interacting serine-threonine kinase 2"
/protein_id="AAH04553.1"
/db_xref="GeneID:8767"
/db_xref="HGNC:HGNC:10020"
/db_xref="MIM:603455"
/translation="MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQV
AVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGS
LNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHV
KIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVI
TWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQN
PDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLN
IPVNHGPQEESCGSSQLHENSGSPETSRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNH
SWDSTISGSQRAAFCDHKTTPCSSAIINPLSTAGNSERLQPGIAQQWIQSKREDIVNQ
MTEACLNQSLDALLSRDLIMKEDYELVSTKPTRTSKVRQLLDTTDIQGEEFAKVIVQK
LKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM"
BASE COUNT 581 a 425 c 413 g 470 t
ORIGIN
1 gtcagctctg gttcggagaa gcagcggctg gcgtgggcca tccggggaat gggcgccctc
61 gtgacctagt gttgcggggc aaaaagggtc ttgccggcct cgctcgtgca ggggcgtatc
121 tgggcgcctg agcgcggcgt gggagccttg ggagccgccg cagcaggggg cacacccgga
181 accggcctga gcgcccggga ccatgaacgg ggaggccatc tgcagcgccc tgcccaccat
241 tccctaccac aaactcgccg acctgcgcta cctgagccgc ggcgcctctg gcactgtgtc
301 gtccgcccgc cacgcagact ggcgcgtcca ggtggccgtg aagcacctgc acatccacac
361 tccgctgctc gacagtgaaa gaaaggatgt cttaagagaa gctgaaattt tacacaaagc
421 tagatttagt tacattcttc caattttggg aatttgcaat gagcctgaat ttttgggaat
481 agttactgaa tacatgccaa atggatcatt aaatgaactc ctacatagga aaactgaata
541 tcctgatgtt gcttggccat tgagatttcg catcctgcat gaaattgccc ttggtgtaaa
601 ttacctgcac aatatgactc ctcctttact tcatcatgac ttgaagactc agaatatctt
661 attggacaat gaatttcatg ttaagattgc agattttggt ttatcaaagt ggcgcatgat
721 gtccctctca cagtcacgaa gtagcaaatc tgcaccagaa ggagggacaa ttatctatat
781 gccacctgaa aactatgaac ctggacaaaa atcaagggcc agtatcaagc acgatatata
841 tagctatgca gttatcacat gggaagtgtt atccagaaaa cagccttttg aagatgtcac
901 caatcctttg cagataatgt atagtgtgtc acaaggacat cgacctgtta ttaatgaaga
961 aagtttgcca tatgatatac ctcaccgagc acgtatgatc tctctaatag aaagtggatg
1021 ggcacaaaat ccagatgaaa gaccatcttt cttaaaatgt ttaatagaac ttgaaccagt
1081 tttgagaaca tttgaagaga taacttttct tgaagctgtt attcagctaa agaaaacaaa
1141 gttacagagt gtttcaagtg ccattcacct atgtgacaag aagaaaatgg aattatctct
1201 gaacatacct gtaaatcatg gtccacaaga ggaatcatgt ggatcctctc agctccatga
1261 aaatagtggt tctcctgaaa cttcaaggtc cctgccagct cctcaagaca atgatttttt
1321 atctagaaaa gctcaagact gttattttat gaagctgcat cactgtcctg gaaatcacag
1381 ttgggatagc accatttctg gatctcaaag ggctgcattc tgtgatcaca agaccactcc
1441 atgctcttca gcaataataa atccactctc aactgcagga aactcagaac gtctgcagcc
1501 tggtatagcc cagcagtgga tccagagcaa aagggaagac attgtgaacc aaatgacaga
1561 agcctgcctt aaccagtcgc tagatgccct tctgtccagg gacttgatca tgaaagagga
1621 ctatgaactt gttagtacca agcctacaag gacctcaaaa gtcagacaat tactagacac
1681 tactgacatc caaggagaag aatttgccaa agttatagta caaaaattga aagataacaa
1741 acaaatgggt cttcagcctt acccggaaat acttgtggtt tctagatcac catctttaaa
1801 tttacttcaa aataaaagca tgtaagtgac tgtttttcaa gaagaaatgt gtttcataaa
1861 aggatattta taaaaaaaaa aaaaaaaaa
//