LOCUS BC004247 792 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho
family, small GTP binding protein Rac1), mRNA (cDNA clone MGC:10547
IMAGE:3610745), complete cds.
ACCESSION BC004247
VERSION BC004247.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 792)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 792)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 13 Row: e Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38505163.
FEATURES Location/Qualifiers
source 1..792
/db_xref="H-InvDB:HIT000031814"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10547 IMAGE:3610745"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..792
/gene="RAC1"
/gene_synonym="MIG5"
/gene_synonym="p21-Rac1"
/gene_synonym="TC-25"
/db_xref="GeneID:5879"
/db_xref="HGNC:HGNC:9801"
/db_xref="MIM:602048"
CDS 139..717
/gene="RAC1"
/gene_synonym="MIG5"
/gene_synonym="p21-Rac1"
/gene_synonym="TC-25"
/codon_start=1
/product="ras-related C3 botulinum toxin substrate 1 (rho
family, small GTP binding protein Rac1)"
/protein_id="AAH04247.1"
/db_xref="GeneID:5879"
/db_xref="HGNC:HGNC:9801"
/db_xref="MIM:602048"
/translation="MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANV
MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVR
HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLIPITYPQGLAMAKEIGAVKYLECSAL
TQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL"
BASE COUNT 195 a 222 c 202 g 173 t
ORIGIN
1 gcgaggcggc gtggacagcg gccccggcac ccagcgcccc gccgcccgca agccgcgcgc
61 ccgtccgccg cgccccgagc ccgccgcttc ctatctcagc gccctgccgc cgccgccgcg
121 gcccagcgag cggccctgat gcaggccatc aagtgtgtgg tggtgggaga cggagctgta
181 ggtaaaactt gcctactgat cagttacaca accaatgcat ttcctggaga atatatccct
241 actgtctttg acaattattc tgccaatgtt atggtagatg gaaaaccggt gaatctgggc
301 ttatgggata cagctggaca agaagattat gacagattac gccccctatc ctatccgcaa
361 acagatgtgt tcttaatttg cttttccctt gtgagtcctg catcatttga aaatgtccgt
421 gcaaagtggt atcctgaggt gcggcaccac tgtcccaaca ctcccatcat cctagtggga
481 actaaacttg atcttaggga tgataaagac acgatcgaga aactgaagga gaagaagctg
541 attcccatca cctatccgca gggtctagcc atggctaagg agattggtgc tgtaaaatac
601 ctggagtgct cggcgctcac acagcgaggc ctcaagacag tgtttgacga agcgatccga
661 gcagtcctct gcccgcctcc cgtgaagaag aggaagagaa aatgcctgct gttgtaaatg
721 tctcagcccc tcgttcttgg tcctgtccct tggaaccttt gtacgctttg ctcaaaaaaa
781 aaaaaaaaaa aa
//