LOCUS BC003653 1263 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens presenilin associated, rhomboid-like, mRNA (cDNA clone
MGC:4756 IMAGE:3537438), complete cds.
ACCESSION BC003653
VERSION BC003653.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1263)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1263)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 11 Row: e Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51871612.
FEATURES Location/Qualifiers
source 1..1263
/db_xref="H-InvDB:HIT000031674"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4756 IMAGE:3537438"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1263
/gene="PARL"
/gene_synonym="PRO2207"
/gene_synonym="PSARL1"
/gene_synonym="PSENIP2"
/gene_synonym="RHBDS1"
/db_xref="GeneID:55486"
/db_xref="HGNC:HGNC:18253"
/db_xref="MIM:607858"
CDS 50..1039
/gene="PARL"
/gene_synonym="PRO2207"
/gene_synonym="PSARL1"
/gene_synonym="PSENIP2"
/gene_synonym="RHBDS1"
/codon_start=1
/product="presenilin associated, rhomboid-like"
/protein_id="AAH03653.1"
/db_xref="GeneID:55486"
/db_xref="HGNC:HGNC:18253"
/db_xref="MIM:607858"
/translation="MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFN
FFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPL
FFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWN
NLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATG
RYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILG
WKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK"
BASE COUNT 339 a 255 c 345 g 324 t
ORIGIN
1 ggcacgaggg ttggtaaggt cgggccatgg tggggcagag gttgggaaga tggcgtggcg
61 aggctgggcg cagagaggct ggggctgcgg ccaggcgtgg ggtgcgtcgg tgggcggccg
121 cagctgcgag gagctcactg cggtcctaac cccgccgcag ctcctcggac gcaggtttaa
181 cttctttatt caacaaaaat gcggattcag aaaagcaccc aggaaggttg aacctcgaag
241 atcagaccca gggacaagtg gtgaagcata caagagaagt gctttgattc ctcctgtgga
301 agaaacagtc ttttatcctt ctccctatcc tataaggagt ctcataaaac ctttattttt
361 tactgttggg tttacaggct gtgcatttgg atcagctgct atttggcaat atgaatcact
421 gaaatccagg gtccagagtt attttgatgg tataaaagct gattggttgg atagcataag
481 accacaaaaa gaaggagact tcagaaagga gattaacaag tggtggaata acctaagtga
541 tggccagcgg actgtgacag gtattatagc tgcaaatgtc cttgtattct gtttatggag
601 agtaccttct ctgcagcgga caatgatcag atatttcaca tcgaatccag cctcaagtgt
661 tatttccaat tttgtcagtt acgtgggtaa agttgccaca ggaagatatg gaccatcact
721 tggtgcatct ggtgccatca tgacagtcct cgcagctgtc tgcactaaga tcccagaagg
781 gaggcttgcc attattttcc ttccgatgtt cacgttcaca gcagggaatg ccctgaaagc
841 cattatcgcc atggatacag caggaatgat cctgggatgg aaattttttg atcatgcggc
901 acatcttggg ggagctcttt ttggaatatg gtatgttact tacggtcatg aactgatttg
961 gaagaacagg gagccgctag tgaaaatctg gcatgaaata aggactaatg gcccaaaaaa
1021 aggaggtggc tctaagtaaa actgggattg gacagtagtg gtgcatctgg tccttgccgc
1081 ctgagagccc caggagacat cggctagagt gaccatggct atgctcccgt ctggaagatg
1141 ccagcatctg gcctcccact gttttcagct gtgtccccca gtccgtgtct ttttagaatg
1201 tgaatgatga taaagttgtg aaataaaggt ttctatctag tttgtaaaaa aaaaaaaaaa
1261 aaa
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