LOCUS BC003644 1386 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cyclin-dependent kinase 4, mRNA (cDNA clone MGC:4678
IMAGE:3532812), complete cds.
ACCESSION BC003644
VERSION BC003644.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1386)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1386)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC003644.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 11 Row: d Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16936531.
FEATURES Location/Qualifiers
source 1..1386
/db_xref="H-InvDB:HIT000031668"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4678 IMAGE:3532812"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1386
/gene="CDK4"
/gene_synonym="CMM3"
/gene_synonym="MGC14458"
/gene_synonym="PSK-J3"
/db_xref="GeneID:1019"
/db_xref="HGNC:HGNC:1773"
/db_xref="MIM:123829"
CDS 140..1051
/gene="CDK4"
/gene_synonym="CMM3"
/gene_synonym="MGC14458"
/gene_synonym="PSK-J3"
/codon_start=1
/product="cyclin-dependent kinase 4"
/protein_id="AAH03644.1"
/db_xref="GeneID:1019"
/db_xref="HGNC:HGNC:1773"
/db_xref="MIM:123829"
/translation="MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGG
GGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT
YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFG
LARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNS
EADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEML
TFNPHKRISAFRALQHSYLHKDEGNPE"
BASE COUNT 320 a 365 c 357 g 344 t
ORIGIN
1 ctatggtcgg gccctctgcg tccagctgct ccggaccgag ctcgggtgta tggggccgta
61 ggaaccggct ccggggcccc gataacgggc cgcccccaca gcaccccggg ctggcgtgag
121 ggtctccctt gatctgagaa tggctacctc tcgatatgag ccagtggctg aaattggtgt
181 cggtgcctat gggacagtgt acaaggcccg tgatccccac agtggccact ttgtggccct
241 caagagtgtg agagtcccca atggaggagg aggtggagga ggccttccca tcagcacagt
301 tcgtgaggtg gctttactga ggcgactgga ggcttttgag catcccaatg ttgtccggct
361 gatggacgtc tgtgccacat cccgaactga ccgggagatc aaggtaaccc tggtgtttga
421 gcatgtagac caggacctaa ggacatatct ggacaaggca cccccaccag gcttgccagc
481 cgaaacgatc aaggatctga tgcgccagtt tctaagaggc ctagatttcc ttcatgccaa
541 ttgcatcgtt caccgagatc tgaagccaga gaacattctg gtgacaagtg gtggaacagt
601 caagctggct gactttggcc tggccagaat ctacagctac cagatggcac ttacacccgt
661 ggttgttaca ctctggtacc gagctcccga agttcttctg cagtccacat atgcaacacc
721 tgtggacatg tggagtgttg gctgtatctt tgcagagatg tttcgtcgaa agcctctctt
781 ctgtggaaac tctgaagccg accagttggg caaaatcttt gacctgattg ggctgcctcc
841 agaggatgac tggcctcgag atgtatccct gccccgtgga gcctttcccc ccagagggcc
901 ccgcccagtg cagtcggtgg tacctgagat ggaggagtcg ggagcacagc tgctgctgga
961 aatgctgact tttaacccac acaagcgaat ctctgccttt cgagctctgc agcactctta
1021 tctacataag gatgaaggta atccggagtg agcaatggag tggctgccat ggaaggaaga
1081 aaagctgcca tttcccttct ggacactgag agggcaatct ttgcctttat ctctgaggct
1141 atggagggtc ctcctccatc tttctacaga gattactttg ctgccttaat gacattcccc
1201 tcccacctct ccttttgagg cttctccttc tccttcccat ttctctacac taaggggtat
1261 gttccctctt gtccctttcc ctacctttat atttggggtc cttttttata caggaaaaac
1321 aaaacaaaga aataatggtc tttttttttt ttttaaaaaa aaaaaaaaaa aaaaaaaaaa
1381 aaaaaa
//