LOCUS BC003596 2508 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens tumor protein p53, mRNA (cDNA clone MGC:646
IMAGE:3544714), complete cds.
ACCESSION BC003596
VERSION BC003596.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2508)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2508)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: f Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8400737.
FEATURES Location/Qualifiers
source 1..2508
/db_xref="H-InvDB:HIT000031628"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:646 IMAGE:3544714"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2508
/gene="TP53"
/gene_synonym="LFS1"
/gene_synonym="p53"
/gene_synonym="TRP53"
/db_xref="GeneID:7157"
/db_xref="HGNC:HGNC:11998"
/db_xref="MIM:191170"
CDS 121..1302
/gene="TP53"
/gene_synonym="LFS1"
/gene_synonym="p53"
/gene_synonym="TRP53"
/codon_start=1
/product="tumor protein p53"
/protein_id="AAH03596.1"
/db_xref="GeneID:7157"
/db_xref="HGNC:HGNC:11998"
/db_xref="MIM:191170"
/translation="MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLM
LSPDDIEQWFTEDPGPDEAPRMPEAAPRVAPAPAAPTPAAPAPAPSWPLSSSVPSQKT
YQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAM
AIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVV
PYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCA
CAGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRG
RERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDS
D"
BASE COUNT 544 a 711 c 619 g 634 t
ORIGIN
1 ccagggagca ggtagctgct gggctccggg gacactttgc gttcgggctg ggagcgtgct
61 ttccacgacg gtgacacgct tccctggatt ggcagccaga ctgccttccg ggtcactgcc
121 atggaggagc cgcagtcaga tcctagcgtc gagccccctc tgagtcagga aacattttca
181 gacctatgga aactacttcc tgaaaacaac gttctgtccc ccttgccgtc ccaagcaatg
241 gatgatttga tgctgtcccc ggacgatatt gaacaatggt tcactgaaga cccaggtcca
301 gatgaagctc ccagaatgcc agaggctgct ccccgcgtgg cccctgcacc agcagctcct
361 acaccggcgg cccctgcacc agccccctcc tggcccctgt catcttctgt cccttcccag
421 aaaacctacc agggcagcta cggtttccgt ctgggcttct tgcattctgg gacagccaag
481 tctgtgactt gcacgtactc ccctgccctc aacaagatgt tttgccaact ggccaagacc
541 tgccctgtgc agctgtgggt tgattccaca cccccgcccg gcacccgcgt ccgcgccatg
601 gccatctaca agcagtcaca gcacatgacg gaggttgtga ggcgctgccc ccaccatgag
661 cgctgctcag atagcgatgg tctggcccct cctcagcatc ttatccgagt ggaaggaaat
721 ttgcgtgtgg agtatttgga tgacagaaac acttttcgac atagtgtggt ggtgccctat
781 gagccgcctg aggttggctc tgactgtacc accatccact acaactacat gtgtaacagt
841 tcctgcatgg gcggcatgaa ccggaggccc atcctcacca tcatcacact ggaagactcc
901 agtggtaatc tactgggacg gaacagcttt gaggtgcgtg tttgtgcctg tgctgggaga
961 gaccggcgca cagaggaaga gaatctccgc aagaaagggg agcctcacca cgagctgccc
1021 ccagggagca ctaagcgagc actgcccaac aacaccagct cctctcccca gccaaagaag
1081 aaaccactgg atggagaata tttcaccctt cagatccgtg ggcgtgagcg cttcgagatg
1141 ttccgagagc tgaatgaggc cttggaactc aaggatgccc aggctgggaa ggagccaggg
1201 gggagcaggg ctcactccag ccacctgaag tccaaaaagg gtcagtctac ctcccgccat
1261 aaaaaactca tgttcaagac agaagggcct gactcagact gacattctcc acttcttgtt
1321 ccccactgac agcctcccac ccccatctct ccctcccctg ccattttggg ttttgggtct
1381 ttgaaccctt gcttgcaata ggtgtgcgtc agaagcaccc aggacttcca tttgctttgt
1441 cccggggctc cactgaacaa gttggcctgc actggtgttt tgttgtgggg aggaggatgg
1501 ggagtaggac ataccagctt agattttaag gtttttactg tgagggatgt ttgggagatg
1561 taagaaatgt tcttgcagtt aagggttagt ttacaatcag ccacattcta ggtaggggcc
1621 cacttcaccg tactaaccag ggaagctgtc cctcactgtt gaattttctc taacttcaag
1681 gcccatatct gtgaaatgct ggcatttgca cctacctcac agagtgcatt gtgagggtta
1741 atgaaataat gtacatctgg ccttgaaacc accttttatt acatggggtc tagaacttga
1801 cccccttgag ggtgcttgtt ccctctccct gttggtcggt gggttggtag tttctacagt
1861 tgggcagctg gttaggtaga gggagttgtc aagtctctgc tggcccagcc aaaccctgtc
1921 tgacaacctc ttggtgaacc ttagtaccta aaaggaaatc tcaccccatc ccacaccctg
1981 gaggatttca tctcttgtat atgatgatct ggatccacca agacttgttt tatgctcagg
2041 gtcaatttct tttttctttt tttttttttt tttctttttc tttgagactg ggtctcgctt
2101 tgttgcccag gctggagtgg agtggcgtga tcttggctta ctgcagcctt tgcctccccg
2161 gctcgagcag tcctgcctca gcctccggag tagctgggac cacaggttca tgccaccatg
2221 gccagccaac ttttgcatgt tttgtagaga tggggtctca cagtgttgcc caggctggtc
2281 tcaaactcct gggctcaggc gatccacctg tctcagcctc ccagagtgct gggattacaa
2341 ttgtgagcca ccacgtccag ctggaagggt caacatcttt tacattctgc aagcacatct
2401 gcattttcac cccacccttc ccctccttct ccctttttat atcccatttt tatatcgatc
2461 tcttatttta caataaaact ttgctgccaa aaaaaaaaaa aaaaaaaa
//