LOCUS BC003591 1627 bp mRNA linear HUM 21-JUL-2006
DEFINITION Homo sapiens single immunoglobulin and toll-interleukin 1 receptor
(TIR) domain, mRNA (cDNA clone MGC:4338 IMAGE:2821373), complete
cds.
ACCESSION BC003591
VERSION BC003591.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1627)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1627)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 9 Row: n Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11141876.
FEATURES Location/Qualifiers
source 1..1627
/db_xref="H-InvDB:HIT000031624"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4338 IMAGE:2821373"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1627
/gene="SIGIRR"
/gene_synonym="TIR8"
/db_xref="GeneID:59307"
/db_xref="HGNC:HGNC:30575"
/db_xref="MIM:605478"
CDS 157..1389
/gene="SIGIRR"
/gene_synonym="TIR8"
/codon_start=1
/product="single immunoglobulin and toll-interleukin 1
receptor (TIR) domain"
/protein_id="AAH03591.1"
/db_xref="GeneID:59307"
/db_xref="HGNC:HGNC:30575"
/db_xref="MIM:605478"
/translation="MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSL
PSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQN
ISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN
DGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNL
SRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLL
RQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVRYRPVEGDPQTQLQDDKDPMLIL
RGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGS
RNYSARTDFYCLVSKDDM"
BASE COUNT 325 a 524 c 486 g 292 t
ORIGIN
1 aagcctctga cctgtccagg tgccctgtcc agctgactgc aaggacagag aggagtcctg
61 cccagctctt ggatcagtct gctggccgag gagcccggtg gagccagggg tgaccctgga
121 gcccagcctg ccccgaggag gccccggctc agagccatgc caggtgtctg tgatagggcc
181 cctgacttcc tctccccgtc tgaagaccag gtgctgaggc ctgccttggg cagctcagtg
241 gctctgaact gcacggcttg ggtagtctct gggccccact gctccctgcc ttcagtccag
301 tggctgaaag acgggcttcc attgggaatt gggggccact acagcctcca cgagtactcc
361 tgggtcaagg ccaacctgtc agaggtgctt gtgtccagtg tcctgggggt caacgtgacc
421 agcactgaag tctatggggc cttcacctgc tccatccaga acatcagctt ctcctccttc
481 actcttcaga gagctggccc tacaagccac gtggctgcgg tgctggcctc cctcctggtc
541 ctgctggccc tgctgctggc cgccctgctc tatgtcaagt gccgtctcaa cgtgctgctc
601 tggtaccagg acgcgtatgg ggaggtggag ataaacgacg ggaagctcta cgacgcctac
661 gtctcctaca gcgactgccc cgaggaccgc aagttcgtga acttcatcct aaagccgcag
721 ctggagcggc gtcggggcta caagctcttc ctggacgacc gcgacctcct gccgcgcgct
781 gagccctccg ccgacctctt ggtgaacctg agccgctgcc gacgcctcat cgtggtgctt
841 tcggacgcct tcctgagccg ggcctggtgc agccacagct tccgggaggg cctgtgccgg
901 ctgctggagc tcacccgcag acccatcttc atcaccttcg agggccagag gcgcgacccc
961 gcgcacccgg cgctccgcct gctgcgccag caccgccacc tggtgacctt gctgctctgg
1021 aggcccggct ccgtgactcc ttcctccgat ttttggaaag aagtgcagct ggcgctgccg
1081 cggaaggtgc ggtacaggcc ggtggaagga gacccccaga cgcagctgca ggacgacaag
1141 gaccccatgc tgattcttcg aggccgagtc cctgagggcc gggccctgga ctcagaggtg
1201 gacccggacc ctgagggcga cctgggtgtc cgggggcctg tttttggaga gccatcagct
1261 ccaccgcaca ccagtggggt ctcgctggga gagagccgga gcagcgaagt ggacgtctcg
1321 gatctcggct cgcgaaacta cagtgcccgc acagacttct actgcctggt gtccaaggat
1381 gatatgtagc tcccacccca gagtgcagga tcatagggac agcgggggcc agggcagcgg
1441 cgtcgctcct ctgctcaaca ggaccacaac ccctgccagc agccctggga ccctgccagc
1501 agccctggga aaaggctgtg gcctcagggc gcctcccagt gccagaaaat aaagtccttt
1561 tggattctga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1621 aaaaaac
//