LOCUS BC003576 3124 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens actinin, alpha 1, mRNA (cDNA clone MGC:2358
IMAGE:3547017), complete cds.
ACCESSION BC003576
VERSION BC003576.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3124)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3124)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: p Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 12025669.
FEATURES Location/Qualifiers
source 1..3124
/db_xref="H-InvDB:HIT000031614"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2358 IMAGE:3547017"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3124
/gene="ACTN1"
/db_xref="GeneID:87"
/db_xref="HGNC:HGNC:163"
/db_xref="MIM:102575"
CDS 243..2921
/gene="ACTN1"
/codon_start=1
/product="actinin, alpha 1"
/protein_id="AAH03576.1"
/db_xref="GeneID:87"
/db_xref="HGNC:HGNC:163"
/db_xref="MIM:102575"
/translation="MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSH
LRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIAS
KGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAP
YKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDI
PKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLM
EDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQL
EINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGYEEWLLNEIRRLERL
DHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDR
VEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETID
QLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERL
AILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHAR
QQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYK
PKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDA
KGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSI
VDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQ
AEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL"
BASE COUNT 779 a 936 c 896 g 513 t
ORIGIN
1 ggagattagg tccaagcgcc cgcccagagg caggcagtcc gcgagcccag ccgccgctgt
61 cgccgccagt agcagccttc gccagcagcg ccgcggcgga accgggcgca ggggagcgag
121 cccggccccg ccagcccagc ccagcccagc ccagccctac tccctcccca cgccagggca
181 gcagccgttg ctcagagaga aggtggagga agaaatccag accctagcac gcgcgcacca
241 tcatggacca ttatgattct cagcaaacca acgattacat gcagccagaa gaggactggg
301 accgggacct gctcctggac ccggcctggg agaagcagca gagaaagaca ttcacggcat
361 ggtgtaactc ccacctccgg aaggcgggga cacagatcga gaacatcgaa gaggacttcc
421 gggatggcct gaagctcatg ctgctgctgg aggtcatctc aggtgaacgc ttggccaagc
481 cagagcgagg caagatgaga gtgcacaaga tctccaacgt caacaaggcc ctggatttca
541 tagccagcaa aggcgtcaaa ctggtgtcca tcggagccga agaaatcgtg gatgggaatg
601 tgaagatgac cctgggcatg atctggacca tcatcctgcg ctttgccatc caggacatct
661 ccgtggaaga gacttcagcc aaggaagggc tgctcctgtg gtgtcagaga aagacagccc
721 cttacaaaaa tgtcaacatc cagaacttcc acataagctg gaaggatggc ctcggcttct
781 gtgctttgat ccaccgacac cggcccgagc tgattgacta cgggaagctg cggaaggatg
841 atccactcac aaatctgaat acggcttttg acgtggcaga gaagtacctg gacatcccca
901 agatgctgga tgccgaagac atcgttggaa ctgcccgacc ggatgagaaa gccatcatga
961 cttacgtgtc tagcttctac cacgccttct ctggagccca gaaggcggag acagcagcca
1021 atcgcatctg caaggtgttg gccgtcaacc aggagaacga gcagcttatg gaagactacg
1081 agaagctggc cagtgatctg ttggagtgga tccgccgcac aatcccgtgg ctggagaacc
1141 gggtgcccga gaacaccatg catgccatgc aacagaagct ggaggacttc cgggactacc
1201 ggcgcctgca caagccgccc aaggtgcagg agaagtgcca gctggagatc aacttcaaca
1261 cgctgcagac caagctgcgg ctcagcaacc ggcctgcctt catgccctct gagggcagga
1321 tggtctcgga catcaacaat gcctggggct gcctggagca ggtggagaag ggctatgagg
1381 agtggttgct gaatgagatc cggaggctgg agcgactgga ccacctggca gagaagttcc
1441 ggcagaaggc ctccatccac gaggcctgga ctgacggcaa agaggccatg ctgcgacaga
1501 aggactatga gaccgccacc ctctcggaga tcaaggccct gctcaagaag catgaggcct
1561 tcgagagtga cctggctgcc caccaggacc gtgtggagca gattgccgcc atcgcacagg
1621 agctcaatga gctggactat tatgactcac ccagtgtcaa cgcccgttgc caaaagatct
1681 gtgaccagtg ggacaatctg ggggccctaa ctcagaagcg aagggaagct ctggagcgga
1741 ccgagaaact gctggagacc attgaccagc tgtacttgga gtatgccaag cgggctgcac
1801 ccttcaacaa ctggatggag ggggccatgg aggacctgca ggacaccttc attgtgcaca
1861 ccattgagga gatccaggga ctgaccacag cccatgagca gttcaaggcc accctccctg
1921 atgccgacaa ggagcgcctg gccatcctgg gcatccacaa tgaggtgtcc aagattgtcc
1981 agacctacca cgtcaatatg gcgggcacca acccctacac aaccatcacg cctcaggaga
2041 tcaatggcaa atgggaccac gtgcggcagc tggtgcctcg gagggaccaa gctctgacgg
2101 aggagcatgc ccgacagcag cacaatgaga ggctacgcaa gcagtttgga gcccaggcca
2161 atgtcatcgg gccctggatc cagaccaaga tggaggagat cgggaggatc tccattgaga
2221 tgcatgggac cctggaggac cagctcagcc acctgcggca gtatgagaag agcatcgtca
2281 actacaagcc aaagattgat cagctggagg gcgaccacca gctcatccag gaggcgctca
2341 tcttcgacaa caagcacacc aactacacca tggagcacat ccgtgtgggc tgggagcagc
2401 tgctcaccac catcgccagg accatcaatg aggtagagaa ccagatcctg acccgggatg
2461 ccaagggcat cagccaggag cagatgaatg agttccgggc ctccttcaac cactttgacc
2521 gggatcactc cggcacactg ggtcccgagg agttcaaagc ctgcctcatc agcttgggtt
2581 atgatattgg caacgacccc cagggagaag cagaatttgc ccgcatcatg agcattgtgg
2641 accccaaccg cctgggggta gtgacattcc aggccttcat tgacttcatg tcccgcgaga
2701 cagccgacac agatacagca gaccaagtca tggcttcctt caagatcctg gctggggaca
2761 agaactacat taccatggac gagctgcgcc gcgagctgcc acccgaccag gctgagtact
2821 gcatcgcgcg gatggccccc tacaccggcc ccgactccgt gccaggtgct ctggactaca
2881 tgtccttctc cacggcgctg tacggcgaga gtgacctcta atccaccccg cccggccgcc
2941 ctcgtcttgt gcgccgtgcc ctgccttgca cctccgccgt cgcccatctc ctgcctgggt
3001 tcggtttcag ctcccagcct ccacccgggt gagctggggc ccacgtggca tcgatcctcc
3061 ctgcccgcga agtgacagtt tacaaaatta ttttctgcaa aaaaaaaaaa aaaaaaaaaa
3121 aaaa
//