LOCUS BC003175 3022 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens N-myc downstream regulated 1, mRNA (cDNA clone
MGC:4412 IMAGE:2957847), complete cds.
ACCESSION BC003175
VERSION BC003175.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3022)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3022)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 9 Row: h Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 37655182.
FEATURES Location/Qualifiers
source 1..3022
/db_xref="H-InvDB:HIT000031489"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4412 IMAGE:2957847"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3022
/gene="NDRG1"
/gene_synonym="CMT4D"
/gene_synonym="DRG1"
/gene_synonym="GC4"
/gene_synonym="HMSNL"
/gene_synonym="NDR1"
/gene_synonym="NMSL"
/gene_synonym="PROXY1"
/gene_synonym="RIT42"
/gene_synonym="RTP"
/gene_synonym="TARG1"
/gene_synonym="TDD5"
/db_xref="GeneID:10397"
/db_xref="HGNC:HGNC:7679"
/db_xref="MIM:605262"
CDS 118..1302
/gene="NDRG1"
/gene_synonym="CMT4D"
/gene_synonym="DRG1"
/gene_synonym="GC4"
/gene_synonym="HMSNL"
/gene_synonym="NDR1"
/gene_synonym="NMSL"
/gene_synonym="PROXY1"
/gene_synonym="RIT42"
/gene_synonym="RTP"
/gene_synonym="TARG1"
/gene_synonym="TDD5"
/codon_start=1
/product="N-myc downstream regulated 1"
/protein_id="AAH03175.1"
/db_xref="GeneID:10397"
/db_xref="HGNC:HGNC:7679"
/db_xref="MIM:605262"
/translation="MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSV
HVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDG
AASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGL
VLINVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVND
MNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKL
DPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSV
TSLDGTRSRSHTSEGTRSRSHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEV
SC"
BASE COUNT 681 a 840 c 807 g 694 t
ORIGIN
1 ctggtgctga agctcgtcag ttcaccatcc gccctcggct tccgcggggc gctgggccgc
61 cagcctcggc accgtccttt cctttctccc tcgcgttagg caggtgacag cagggacatg
121 tctcgggaga tgcaggatgt agacctcgct gaggtgaagc ctttggtgga gaaaggggag
181 accatcaccg gcctcctgca agagtttgat gtccaggagc aggacatcga gactttacat
241 ggctctgttc acgtcacgct gtgtgggact cccaagggaa accggcctgt catcctcacc
301 taccatgaca tcggcatgaa ccacaaaacc tgctacaacc ccctcttcaa ctacgaggac
361 atgcaggaga tcacccagca ctttgccgtc tgccacgtgg acgcccctgg ccagcaggac
421 ggcgcagcct ccttccccgc agggtacatg tacccctcca tggatcagct ggctgaaatg
481 cttcctggag tccttcaaca gtttgggctg aaaagcatta ttggcatggg aacaggagca
541 ggcgcctaca tcctaactcg atttgctcta aacaaccctg agatggtgga gggccttgtc
601 cttatcaacg tgaacccttg tgcggaaggc tggatggact gggccgcctc caagatctca
661 ggatggaccc aagctctgcc ggacatggtg gtgtcccacc tttttgggaa ggaagaaatg
721 cagagtaacg tggaagtggt ccacacctac cgccagcaca ttgtgaatga catgaacccc
781 ggcaacctgc acctgttcat caatgcctac aacagccggc gcgacctgga gattgagcga
841 ccaatgccgg gaacccacac agtcaccctg cagtgccctg ctctgttggt ggttggggac
901 agctcgcctg cagtggatgc cgtggtggag tgcaactcaa aattggaccc aacaaagacc
961 actctcctca agatggcgga ctgtggcggc ctcccgcaga tctcccagcc ggccaagctc
1021 gctgaggcct tcaagtactt cgtgcagggc atgggataca tgccctcggc tagcatgacc
1081 cgcctgatgc ggtcccgcac agcctctggt tccagcgtca cttctctgga tggcacccgc
1141 agccgctccc acaccagcga gggcacccga agccgctccc acaccagcga gggcacccgc
1201 agccgctcgc acaccagcga gggggcccac ctggacatca cccccaactc gggtgctgct
1261 gggaacagcg ccgggcccaa gtccatggag gtctcctgct aggcggcctg cccagctgcc
1321 gcccccggac tctgatctct gtagtggccc cctcctcccc ggcccctttt cgccccctgc
1381 ctgccatact gcgcctaact cggtattaat ccaaagctta ttttgtaaga gtgagctctg
1441 gtggagacaa atgaggtcta ttacgtgggt gccctctcca aaggcggggt ggcggtggac
1501 caaaggaagg aagcaagcat ctccgcatcg catcctcttc cattaaccag tggccggttg
1561 ccactctcct cccctccctc agagacacca aactgccaaa aacaagacgc gtagcagcac
1621 acacttcaca aagccaagcc taggccgccc tgagcatcct ggttcaaacg ggtgcctggt
1681 cagaaggcca gccgcccact tcccgtttcc tctttaactg aggagaagct gatccagttt
1741 ccggaaacaa aatccttttc tcatttgggg aggggggtaa tagtgacatg caggcacctc
1801 ttttaaacag gcaaaacagg aagggggaaa aggtgggatt catgtcgagg ctagaggcat
1861 ttggaacaac aaatctacgt agttaacttg aagaaaccga tttttaaagt tggtgcatct
1921 agaaagcttt gaatgcagaa gcaaacaagc ttgatttttc tagcatcctc ttaatgtgca
1981 gcaaaagcag gcaacaaaat ctcctggctt tacagacaaa aatatttcag caaacgttgg
2041 gcatcatggt ttttgaaggc tttagttctg ctttctgcct ctcctccaca gccccaacct
2101 cccacccctg atacatgagc cagtgattat tcttgttcag ggagaagatc atttagattt
2161 gttttgcatt ccttagaatg gagggcaaca ttccacagct gccctggctg tgatgagtgt
2221 ccttgcaggg gccggagtag gagcactggg gtgggggcgg aattggggtt actcgatgta
2281 agggattcct tgttgttgtg ttgagatcca gtgcagttgt gatttctgtg gatcccagct
2341 tggttccagg aattttgtgt gattggctta aatccagttt tcaatcttcg acagctgggc
2401 tggaacgtga actcagtagc tgaacctgtc tgacccggtc acgttcttgg atcctcagaa
2461 ctcttgctct tgtcggggtg ggggtgggaa ctcacgtggg gagcggtggc tgagaaaatg
2521 taaggattct ggaatacata ttccatggga ctttccttcc ctctcctgct tcctcttttc
2581 ctgctcccta acctttcgcc gaatggggca gcaccactga cgtttctggg cggccagtgc
2641 ggctgccagg ttcctgtact actgccttgt acttttcatt ttggctcacc gtggattttc
2701 tcataggaag tttggtcaga gtgaattgaa tattgtaagt cagccactgg gacccgagga
2761 tttctgggac cccgcagttg ggaggaggaa gtagtccagc cttccaggtg gcgtgagagg
2821 caatgactcg ttacctgccg cccatcacct tggaggcctt ccctggcctt gagtagaaaa
2881 gtcggggatc ggggcaagag aggctgagta cggatgggaa actattgtgc acaagtcttt
2941 ccagaggagt ttcttaatga gatatttgta tttatttcca gaccaataaa tttgtaactt
3001 tgcaaaaaaa aaaaaaaaaa aa
//