LOCUS BC003109 2180 bp mRNA linear HUM 01-SEP-2006
DEFINITION Homo sapiens megakaryocyte-associated tyrosine kinase, mRNA (cDNA
clone MGC:2101 IMAGE:3357648), complete cds.
ACCESSION BC003109
VERSION BC003109.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2180)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2180)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: e Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21450845.
FEATURES Location/Qualifiers
source 1..2180
/db_xref="H-InvDB:HIT000031437"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2101 IMAGE:3357648"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2180
/gene="MATK"
/gene_synonym="CHK"
/gene_synonym="CTK"
/gene_synonym="DKFZp434N1212"
/gene_synonym="HHYLTK"
/gene_synonym="HYL"
/gene_synonym="HYLTK"
/gene_synonym="Lsk"
/gene_synonym="MGC1708"
/gene_synonym="MGC2101"
/db_xref="GeneID:4145"
/db_xref="HGNC:HGNC:6906"
/db_xref="MIM:600038"
CDS 400..1923
/gene="MATK"
/gene_synonym="CHK"
/gene_synonym="CTK"
/gene_synonym="DKFZp434N1212"
/gene_synonym="HHYLTK"
/gene_synonym="HYL"
/gene_synonym="HYLTK"
/gene_synonym="Lsk"
/gene_synonym="MGC1708"
/gene_synonym="MGC2101"
/codon_start=1
/product="megakaryocyte-associated tyrosine kinase"
/protein_id="AAH03109.1"
/db_xref="GeneID:4145"
/db_xref="HGNC:HGNC:6906"
/db_xref="MIM:600038"
/translation="MAGRGSLVSWRAFHGCDSAEELPRVSPRFLRAWHPPPVSARMPT
RRWAPGTQCITKCEHTRPKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAA
GALREREALSADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCV
SFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKS
AEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDE
TAVMTKMQHENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSL
HVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTA
PEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCP
GPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGAPASVSGQDADGSTSPRSQEP"
BASE COUNT 436 a 689 c 724 g 331 t
ORIGIN
1 ggccggcggc ggcggcggcg cgcggaggag accgcagtgc ggccggcgct aggacccgcg
61 ggggcctccc aggccgcggc gcctcgcgct ttcccccact ccccgaccct tcttcgcccc
121 caaaatgagg aaacggagca actcgctcca agttgtgcag ccgggaccgc ctcggggtgt
181 gcagccggct cgcggaggcc ctcctggggg cgggcgcggg gcgcggctcg ggggcgcccc
241 ctgagcagaa aacaggaaga accaggctcg gtccagtggc acccagctcc ctacctcctg
301 tgccagccgc ctggcctgtg gcaggccatt cccagcgtcc ccgactgtga ccacttgctc
361 agtgtgcctc tcacctgcct cagtttccct ctgggggcga tggcggggcg aggctctctg
421 gtttcctggc gggcatttca cggctgtgat tctgctgagg aacttccccg ggtgagcccc
481 cgcttcctcc gagcctggca cccccctccc gtctcagcca ggatgccaac gaggcgctgg
541 gccccgggca cccagtgtat caccaaatgc gagcacaccc gccccaagcc aggggagctg
601 gccttccgca agggcgacgt ggtcaccatc ctggaggcct gcgagaacaa gagctggtac
661 cgcgtcaagc accacaccag tggacaggag gggctgctgg cagctggggc gctgcgggag
721 cgggaggccc tctccgcaga ccccaagctc agcctcatgc cgtggttcca cgggaagatc
781 tcgggccagg aggctgtcca gcagctgcag cctcccgagg atgggctgtt cctggtgcgg
841 gagtccgcgc gccaccccgg cgactacgtc ctgtgcgtga gctttggccg cgacgtcatc
901 cactaccgcg tgctgcaccg cgacggccac ctcacaatcg atgaggccgt gttcttctgc
961 aacctcatgg acatggtgga gcattacagc aaggacaagg gcgctatctg caccaagctg
1021 gtgagaccaa agcggaaaca cgggaccaag tcggccgagg aggagctggc cagggcgggc
1081 tggttactga acctgcagca tttgacattg ggagcacaga tcggagaggg agagtttgga
1141 gctgtcctgc agggtgagta cctggggcaa aaggtggccg tgaagaatat caagtgtgat
1201 gtgacagccc aggccttcct ggacgagacg gccgtcatga cgaagatgca acacgagaac
1261 ctggtgcgtc tcctgggcgt gatcctgcac caggggctgt acattgtcat ggagcacgtg
1321 agcaagggca acctggtgaa ctttctgcgg acccggggtc gagccctcgt gaacaccgct
1381 cagctcctgc agttttctct gcacgtggcc gagggcatgg agtacctgga gagcaagaag
1441 cttgtgcacc gcgacctggc cgcccgcaac atcctggtct cagaggacct ggtggccaag
1501 gtcagcgact ttggcctggc caaagccgag cggaaggggc tagactcaag ccggctgccc
1561 gtcaagtgga cggcgcccga ggctctcaaa cacgggaagt tcaccagcaa gtcggatgtc
1621 tggagttttg gggtgctgct ctgggaggtc ttctcatatg gacgggctcc gtaccctaaa
1681 atgtcactga aagaggtgtc ggaggccgtg gagaaggggt accgcatgga accccccgag
1741 ggctgtccag gccccgtgca cgtcctcatg agcagctgct gggaggcaga gcccgcccgc
1801 cggccaccct tccgcaaact ggccgagaag ctggcccggg agctacgcag tgcaggtgcc
1861 ccagcctccg tctcagggca ggacgccgac ggctccacct cgccccgaag ccaggagccc
1921 tgaccccacc cggtggggcc cttggcccca gaggaccgag agagtggaga gtgcggcgtg
1981 ggggcactga ccaggcccaa ggagggtcca ggcgggcaag tcatcctcct ggtgcccaca
2041 gcaggggctg gcccacgtag ggggctctgg gcggcccgtg gacaccccag acctgcgaag
2101 gatgatcgcc cgataaagac ggattctaag gacaaaaaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa aaaaaaaaaa
//