LOCUS BC003072 2210 bp mRNA linear HUM 22-FEB-2007
DEFINITION Homo sapiens ret proto-oncogene, mRNA (cDNA clone IMAGE:3507569),
complete cds.
ACCESSION BC003072
VERSION BC003072.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2210)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2210)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC003072.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: i Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 50593520
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..2210
/db_xref="H-InvDB:HIT000031405"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3507569"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2210
/gene="RET"
/gene_synonym="CDHF12"
/gene_synonym="PTC"
/gene_synonym="RET-ELE1"
/gene_synonym="RET51"
/db_xref="GeneID:5979"
/db_xref="HGNC:HGNC:9967"
/db_xref="MIM:164761"
CDS 181..1557
/gene="RET"
/gene_synonym="CDHF12"
/gene_synonym="PTC"
/gene_synonym="RET-ELE1"
/gene_synonym="RET51"
/codon_start=1
/product="RET protein"
/protein_id="AAH03072.1"
/db_xref="GeneID:5979"
/db_xref="HGNC:HGNC:9967"
/db_xref="MIM:164761"
/translation="MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQ
AAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLD
HSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSL
KPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAP
DSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGV
DTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHW
PNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLH
FNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCLADLTGDAVSGRDEARSSGL
GSQKHPGS"
BASE COUNT 426 a 692 c 660 g 432 t
ORIGIN
1 ccgaagcagg gcgcgcagca gcgctgagtg ccccggaacg tgcgtcgcgc ccccagtgtc
61 cgtcgcgtcc gccgcgcccc gggcggggat ggggcggcca gactgagcgc cgcacccgcc
121 atccagaccc gccggcccta gccgcagtcc ctccagccgt ggccccagcg cgcacgggcg
181 atggcgaagg cgacgtccgg tgccgcgggg ctgcgtctgc tgttgctgct gctgctgccg
241 ctgctaggca aagtggcatt gggcctctac ttctcgaggg atgcttactg ggagaagctg
301 tatgtggacc aggcggccgg cacgcccttg ctgtacgtcc atgccctgcg ggacgcccct
361 gaggaggtgc ccagcttccg cctgggccag catctctacg gcacgtaccg cacacggctg
421 catgagaaca actggatctg catccaggag gacaccggcc tcctctacct taaccggagc
481 ctggaccata gctcctggga gaagctcagt gtccgcaacc gcggctttcc cctgctcacc
541 gtctacctca aggtcttcct gtcacccaca tcccttcgtg agggcgagtg ccagtggcca
601 ggctgtgccc gcgtatactt ctccttcttc aacacctcct ttccagcctg cagctccctc
661 aagccccggg agctctgctt cccagagaca aggccctcct tccgcattcg ggagaaccga
721 cccccaggca ccttccacca gttccgcctg ctgcctgtgc agttcttgtg ccccaacatc
781 agcgtggcct acaggctcct ggagggtgag ggtctgccct tccgctgcgc cccggacagc
841 ctggaggtga gcacgcgctg ggccctggac cgcgagcagc gggagaagta cgagctggtg
901 gccgtgtgca ccgtgcacgc cggcgcgcgc gaggaggtgg tgatggtgcc cttcccggtg
961 accgtgtacg acgaggacga ctcggcgccc accttccccg cgggcgtcga caccgccagc
1021 gccgtggtgg agttcaagcg gaaggaggac accgtggtgg ccacgctgcg tgtcttcgat
1081 gcagacgtgg tacctgcatc aggggagctg gtgaggcggt acacaagcac gctgctcccc
1141 ggggacacct gggcccagca gaccttccgg gtggaacact ggcccaacga gacctcggtc
1201 caggccaacg gcagcttcgt gcgggcgacc gtacatgact ataggctggt tctcaaccgg
1261 aacctctcca tctcggagaa ccgcaccatg cagctggcgg tgctggtcaa tgactcagac
1321 ttccagggcc caggagcggg cgtcctcttg ctccacttca acgtgtcggt gctgccggtc
1381 agcctgcacc tgcccagtac ctactccctc tccgtgagca ggagggctcg ccgatttgcc
1441 cagatcggga aagtctgtgt ggaaaactgc ctggcagatc tcacagggga tgcagtatct
1501 ggccgagatg aagctcgttc atcgggactt ggcagccaga aacatcctgg tagctgaggg
1561 gcggaagatg aagatttcgg atttcggctt gtcccgagat gtttatgaag aggattcgta
1621 cgtgaagagg agccagggtc ggattccagt taaatggatg gcaattgaat ccctttttga
1681 tcatatctac accacgcaaa gtgatgtatg gtcttttggt gtcctgctgt gggagatcgt
1741 gaccctaggg ggaaacccct atcctgggat tcctcctgag cggctcttca accttctgaa
1801 gaccggccac cggatggaga ggccagacaa ctgcagcgag gagatgtact gcctgatgct
1861 gcaatgctgg aagcaggagc cggacaaaag gccggtgttt gcggacatca gcaaagacct
1921 ggagaagatg atggttaaga ggagagacta cttggacctt gcggcgtcca ctccatctga
1981 ctccctgatt tatgacgacg gcctctcaga ggaggagaca ccgctggtgg actgtaataa
2041 tgcccccctc cctcgagccc tcccttccac atggattgaa aacaaactct atggtagaat
2101 ttcccatgca tttactagat tctagcaccg ctgtcccctc tgcactatcc ttcctctctg
2161 tgatgctttt taaaaatgtt tctggtctga acaaaaaaaa aaaaaaaaaa
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