LOCUS BC002921 2340 bp mRNA linear HUM 19-JUN-2008
DEFINITION Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 4, mRNA (cDNA
clone MGC:10333 IMAGE:3956856), complete cds.
ACCESSION BC002921
VERSION BC002921.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2340)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2340)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002921.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 15 Row: e Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62422555.
FEATURES Location/Qualifiers
source 1..2340
/db_xref="H-InvDB:HIT000031290"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10333 IMAGE:3956856"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2340
/gene="PAK4"
/db_xref="GeneID:10298"
/db_xref="HGNC:HGNC:16059"
/db_xref="MIM:605451"
CDS 219..1499
/gene="PAK4"
/codon_start=1
/product="p21 protein (Cdc42/Rac)-activated kinase 4"
/protein_id="AAH02921.1"
/db_xref="GeneID:10298"
/db_xref="HGNC:HGNC:16059"
/db_xref="MIM:605451"
/translation="MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE
ESARRPKPLVDPACITSIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRR
DSPPPPARARQENGMPEKPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFI
KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYN
SYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDI
KSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIW
SLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP
AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR"
BASE COUNT 474 a 763 c 706 g 397 t
ORIGIN
1 ggggattcaa catggcggcg ggagtgtccg cggtggtggc ggtgcaagag agctgaagga
61 ggcgcgaggg cgcggagttc caggccgagc agttaggccg cgagcgactg cggcgccgag
121 ccgatgagta acccgaagcc cctagaggag tggtcacctg cctgagggca cttctgtccc
181 accagcatca gaccaggccg caccgagtcc ccggcaccat gtttgggaag aggaagaagc
241 gggtggagat ctccgcgccg tccaacttcg agcaccgcgt gcacacgggc ttcgaccagc
301 acgagcagaa gttcacgggg ctgccccgcc agtggcagag cctgatcgag gagtcggctc
361 gccggcccaa gcccctcgtc gaccccgcct gcatcacctc catccagccc ggggccccca
421 agaccatcgt gcggggcagc aaaggtgcca aagatggggc cctcacgctg ctgctggacg
481 agtttgagaa catgtcggtg acacgctcca actccctgcg gagagacagc ccgccgccgc
541 ccgcccgtgc ccgccaggaa aatgggatgc cagaaaagcc ccctggcccc cgctcaccac
601 agcgggagcc acagcgagta tcccatgagc agttccgggc tgccctgcag ctggtggtgg
661 acccaggcga cccccgctcc tacctggaca acttcatcaa gattggcgag ggctccacgg
721 gcatcgtgtg catcgccacc gtgcgcagct cgggcaagct ggtggccgtc aagaagatgg
781 acctgcgcaa gcagcagagg cgcgagctgc tcttcaacga ggtggtaatc atgagggact
841 accagcacga gaatgtggtg gagatgtaca acagctacct ggtgggggac gagctctggg
901 tggtcatgga gttcctggaa ggaggcgccc tcaccgacat cgtcacccac accaggatga
961 acgaggagca gatcgcggcc gtgtgccttg cagtgctgca ggccctgtcg gtgctccacg
1021 cccagggcgt catccaccgg gacatcaaga gcgactcgat cctgctgacc catgatggca
1081 gggtgaagct gtcagacttt gggttctgcg cccaggtgag caaggaagtg ccccgaagga
1141 agtcgctggt cggcacgccc tactggatgg ccccagagct catctcccgc cttccctacg
1201 ggccagaggt agacatctgg tcgctgggga taatggtgat tgagatggtg gacggagagc
1261 ccccctactt caacgagcca cccctcaaag ccatgaagat gattcgggac aacctgccac
1321 cccgactgaa gaacctgcac aaggtgtcgc catccctgaa gggcttcctg gaccgcctgc
1381 tggtgcgaga ccctgcccag cgggccacgg cagccgagct gctgaagcac ccattcctgg
1441 ccaaggcagg gccgcctgcc agcatcgtgc ccctcatgcg ccagaaccgc accagatgag
1501 gcccagcgcc cttcccctca accaaagagc cccccgggtc acccccgccc cactgaggcc
1561 agtagggggc caggcctccc actcctccca gcccgggaga tgctccgcgt ggcaccaccc
1621 tccttgctgg gggtagatga gaccctacta ctgaactcca gttttgatct cgtgactttt
1681 agaaaaacac agggactcgt gggagcaagc gaggctccca ggacccccac cctctgggac
1741 aggccctccc ccatgttctt ctgtctccag gaagggcagc ggccctccca tcactggaag
1801 tctgcagtgg gggtcgctgg gggtggagag aacactaaga ggtgaacatg tatgagtgtg
1861 tgcacgcgtg tgagtgtgca tgtgtgtgtg tgtgcaaagg tccagccacc ccgtcctcca
1921 gcccgcaagg ggtgtctggc gccttgcctg acacccagcc ccctctcccc ctgagccatt
1981 gtgggggtcg atcatgaatg tccgaagagt ggccttttcc cgtagccctg cgcccccttt
2041 ctgtggctgg atggggagac aggtcagggc cccccaccct ctccagcccc tgcagcaaat
2101 gactactgca cctggacagc ctcctctttt ctagaagtct atttatattg tcattttata
2161 acactctagc ccctgccctt attgggggac agatggtccc tgtcctgcgg ggtggccctg
2221 gcagaaccac tgcctgaaga accaggttcc tgcccggtca gcgcagcccc agcccgccca
2281 cccctgcctc gagttagttt tacaattaaa acattgtctt gtaaaaaaaa aaaaaaaaaa
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