LOCUS BC002774 3122 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens CDC42 effector protein (Rho GTPase binding) 4, mRNA
(cDNA clone MGC:3740 IMAGE:3617435), complete cds.
ACCESSION BC002774
VERSION BC002774.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3122)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3122)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: d Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 48375181.
FEATURES Location/Qualifiers
source 1..3122
/db_xref="H-InvDB:HIT000258893"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3740 IMAGE:3617435"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3122
/gene="CDC42EP4"
/gene_synonym="BORG4"
/gene_synonym="CEP4"
/gene_synonym="KAIA1777"
/gene_synonym="MGC17125"
/gene_synonym="MGC3740"
/db_xref="GeneID:23580"
/db_xref="HGNC:HGNC:17147"
/db_xref="MIM:605468"
CDS 225..1295
/gene="CDC42EP4"
/gene_synonym="BORG4"
/gene_synonym="CEP4"
/gene_synonym="KAIA1777"
/gene_synonym="MGC17125"
/gene_synonym="MGC3740"
/codon_start=1
/product="CDC42 effector protein (Rho GTPase binding) 4"
/protein_id="AAH02774.1"
/db_xref="GeneID:23580"
/db_xref="HGNC:HGNC:17147"
/db_xref="MIM:605468"
/translation="MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAG
DAFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDM
LGSLRDSALFVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTE
EAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSML
GDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSL
PSHALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERSPAFRGPDRARAA
VSRQPDKEFSFMDEEEEDEIRV"
BASE COUNT 658 a 935 c 880 g 649 t
ORIGIN
1 ggcacgagga aacaaacgcc ggcgctgaca ggggccgcca gcccctccgc cgcgcggagc
61 ccacgaaggg gacagcgcag ccggcccaga gctcgggtct ccggggaccg agccttatga
121 tctcctcatt gcgtccccct ctgcccactg gacttggact tcagatctga ccccagacct
181 gccggctacc tcgggagggc ccacctcccc gcccatccag caagatgcca atcctcaagc
241 aactggtgtc cagctcggtg cactccaagc gccgttcccg agcggacctc acggccgaga
301 tgatcagcgc cccgctgggc gacttccgcc acaccatgca cgttggccgg gccggagacg
361 cctttgggga cacctccttc ctcaatagca aggctggcga gcccgacggc gagtccttgg
421 acgaacagcc ctcttcttca tcttccaaac gcagtctcct gtccaggaag ttccggggca
481 gcaagcggtc acagtcggtg accagggggg agcgggagca gcgtgacatg ctgggctccc
541 tgcgggactc ggccctgttt gtcaagaatg ccatgtccct gccccagctc aatgagaagg
601 aggccgcgga gaagggcacc agtaagctgc ccaagagcct gtcatccagc cccgtgaaga
661 aggccaatga cggggagggc ggcgatgagg aggcgggcac ggaggaggca gtgccccgtc
721 ggaatggggc cgcgggtcca cattcccctg accccctcct cgatgagcag gcctttgggg
781 atctgacaga tctgcctgtc gtgcccaagg ccacgtacgg gctgaagcat gcggagtcca
841 tcatgtcctt ccacatcgac ctggggccct ccatgctggg tgacgtcctc agcatcatgg
901 acaaggagga gtgggacccc gaggaggggg agggtggtta ccatggcgat gagggcgccg
961 ctggcaccat cacccaggct cccccgtacg ccgtggcggc ccctcccctg gcaaggcagg
1021 aaggcaaggc tggcccagac ttgccctccc tcccctccca tgctctggag gatgaggggt
1081 gggcagcagc ggcccccagc cccggctcag cccgcagcat gggcagccac accacacggg
1141 acagcagctc cctctccagc tgcacctcag gcatcctgga ggagcgcagc cctgccttcc
1201 gggggccgga cagggcccgg gctgctgtct caagacagcc agacaaggag ttctccttca
1261 tggatgagga ggaggaggat gaaatccgtg tgtgaggcgg acagtgggtg gccaccggga
1321 gctcttggct gcatcttctc cctgccccca ccccactatg acctttgacc ctacggcgca
1381 ggggcagcca ggacccttga ttcagaccat ggaccctgga ccttgtagat gagggacact
1441 ggcctggccc tcgggtcttc ggaggacgta gggggctggc atgggtgccg actggctgcc
1501 tgacttcatc acgctccctg cacttaggct gcgtgggaca agggctgtgt tgtcacagca
1561 ggaataggtt ttcctctgtt ggcctccctt tcctccaccc tggcctcaaa tggatgccag
1621 atgccaaccc cagttctggc cacgtacagc cagcgggtca gcccagaggc agcctcagct
1681 ccagggctaa ggactctcgg ctcccatttt ctctgctggc gtttctgctg tgcccagcag
1741 tggctgctgg ggaagcagct gcagcaggag ggagacggtc ttgcctctca gcccctccct
1801 gccccacccc agctcctgcc ctggaaatct ggagcccctt ggagctgagc tggacggggg
1861 gccagctgcg agcatgtgca ctaaacgcag ccctttccag gggaagagaa caggatggag
1921 aatggaagga aagcccccca ggcttcgtga attgcaagaa gggacccttc caggatgaca
1981 ctaggaacag ggctagggca ctcgctcagt ccctaggggc ttgtttgttc tttattattg
2041 tgtttaaatc cttatagagc aatatcagga tggtgttaat aggtctgcct cagaatgaga
2101 atcaatcctt ttagaaaacc tttatactaa gcctcctctt cgaaattcac agtggcgatt
2161 agcggactgg agtctggtgg cgattagcgg actggagtct ggggacatcc gtggcaaaga
2221 caccagctca actttagtgc ttcccaactt tatttagaat gacatggggt gggtgtctgg
2281 tgtgtgtgtt ttccctacgc acctcccata gctattaaca actgaggaag gccagtgcag
2341 aatatttttg gagaacgatt ttttttttaa ataatatatc attcctatgg ggggaaagcc
2401 ttttttttct ttttggctga gttattccct ccctcccctc aataccctca gtactgacta
2461 cttccctttc ttttctcagg cctcccccca ccgacttttg aggccagggt tggccagatt
2521 tagcaaaacc aaaacagagt gctgagttaa acgcaaattt caggtaaaca aaagataatt
2581 ttctagcatt aatatgcccc acgcaatatt tggaacactt atgtgaaaaa tgatttgttt
2641 ttctgaaatt cacgtttctc tctgagtcct gtaactgtcc ccgaggggat tgagcagaag
2701 ctcgggtatg agccctgagg ttgactgccg gttatttttc tgtcctggga acagcctgac
2761 ccacctccct gtctccatgt agccagtgag gggaggggga gacacagaac caaccacagc
2821 caggggcgtc cccatggcga ctgtggcccg gcccctcctc tcttgcctga ctctcctctc
2881 ttgcctgact ctagacacta acttagttcc aggttcggtg ccctgttggt gctcctgttt
2941 ccaatagctt aggtcccatg gtgggggagg aacctcaggg gctatgcagc ccccgccagc
3001 tgccctcgaa tcccgtccag gccaattcca gattctaaac tgattttttt catgatattg
3061 tcaaaacagt gaggaaacat taaaaaaaaa agccctaaag caaaaaaaaa aaaaaaaaaa
3121 aa
//