LOCUS BC002755 2736 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens MAP kinase interacting serine/threonine kinase 1, mRNA
(cDNA clone MGC:3690 IMAGE:3629765), complete cds.
ACCESSION BC002755
VERSION BC002755.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2736)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2736)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002755.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: m Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34147650.
FEATURES Location/Qualifiers
source 1..2736
/db_xref="H-InvDB:HIT000031158"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3690 IMAGE:3629765"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2736
/gene="MKNK1"
/gene_synonym="MNK1"
/db_xref="GeneID:8569"
/db_xref="HGNC:HGNC:7110"
/db_xref="MIM:606724"
CDS 165..1562
/gene="MKNK1"
/gene_synonym="MNK1"
/codon_start=1
/product="MAP kinase interacting serine/threonine kinase
1"
/protein_id="AAH02755.1"
/db_xref="GeneID:8569"
/db_xref="HGNC:HGNC:7110"
/db_xref="MIM:606724"
/translation="MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKF
EDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQ
GNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDF
LHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENIL
CESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQAT
FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYE
FPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRN
SSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRAL
AQAGRGEDRSPPTAL"
BASE COUNT 678 a 725 c 694 g 639 t
ORIGIN
1 gcgaccgctc cccggcggga gccagcgaag gtttccatgt cagaggccga tggagaactg
61 aagattgcca cctacgcaca aaggccattg agacacttcg tgtagctgga agacaccaac
121 ttcctgacag gagctttatt tcatttggga tttcaagttt acagatggta tcttctcaaa
181 agttggaaaa acctatagag atgggcagta gcgaacccct tcccatcgca gatggtgaca
241 ggaggaggaa gaagaagcgg aggggccggg ccactgactc cttgccagga aagtttgaag
301 atatgtacaa gctgacctct gaattgcttg gagagggagc ctatgccaaa gttcaaggtg
361 ccgtgagcct acagaatggc aaagagtatg ccgtcaaaat catcgagaaa caagcagggc
421 acagtcggag tagggtgttt cgagaggtgg agacgctgta tcagtgtcag ggaaacaaga
481 acattttgga gctgattgag ttctttgaag atgacacaag gttttacttg gtctttgaga
541 aattgcaagg aggttccatc ttagcccaca tccagaagca aaagcacttc aatgagcgag
601 aagccagccg agtggtgcgg gacgttgctg ctgcccttga cttcctgcat accaaagaca
661 aagtctctct ctgtcaccta ggctggagtg ctatggcgcc atcagggctc actgcagccc
721 caacctccct gggctccagt gatcctccca cctcagcctc ccaagtagct gggactacag
781 gcattgctca tcgtgatctg aaaccagaaa atatattgtg tgaatctcca gaaaaggtgt
841 ctccagtgaa aatctgtgac tttgacttgg gcagtgggat gaaactgaac aactcctgta
901 cccccataac cacaccagag ctgaccaccc catgtggctc tgcagaatac atggcccctg
961 aggtagtgga ggtcttcacg gaccaggcca cattctacga caagcgctgt gacctgtgga
1021 gcctgggcgt ggtcctctac atcatgctga gtggctaccc acccttcgtg ggtcactgcg
1081 gggccgactg tggctgggac cggggcgagg tctgcagggt gtgccagaac aagctgtttg
1141 aaagcatcca ggaaggcaag tatgagtttc ctgacaagga ctgggcacac atctccagtg
1201 aagccaaaga cctcatctcc aagctcctgg tgcgagatgc aaagcagaga cttagcgccg
1261 cccaagttct gcagcaccca tgggtgcagg ggcaagctcc agaaaaggga ctccccacgc
1321 cgcaagtcct ccagaggaac agcagcacaa tggacctgac gctcttcgca gctgaggcca
1381 tcgcccttaa ccgccagcta tctcagcacg aagagaacga actagcagag gagccagagg
1441 cactagctga tggcctctgc tccatgaagc tttcccctcc ctgcaagtca cgcctggccc
1501 ggagacgggc cctggcccag gcaggccgtg gtgaagacag gagcccgccc acagcactct
1561 gaaatgctcc agtcacacct tataggccct aggcctggcc aggcattgtc ccctggaaac
1621 ctgtgtggct aaagtctgct gagcaggcag cagcctctgc tctgtggctc cattcaggct
1681 ttttcatcta cgaaggccct gaggttccca tcaaccccca tttccctagg gtcctggagg
1741 aaaaagcttt ttccaaaggg gttgtctttg aaaaggaaag caatcacttc tcactttgca
1801 taattgcctg cagcaggaac atctcttcac tgggctccac ctgctcaccc gcctgcagat
1861 ctgggatcca gcctgctctc accgctgtag ctgtggcggc tggggctgca gcctgcaggg
1921 agaagcaaga agcatcagtt gacagaggct gccgacacgt gcctcttccc tctcttctct
1981 gtcaccctcc tctggcggtc cttccacctt cctctgtcct ccggatgtcc tctttgcccg
2041 tcttctccct tggctgagca aagccatccc ctcaattcag ggaagggcaa ggagccttcc
2101 tcattcagga aatcaaatca gtcttccggt ctgcagcacg gaaaagcaca taatctttct
2161 ttgctgtgac tgaaatgtat ccctcgttta tcatcccctt tgtttgtgat tgctgctaaa
2221 gtcagtagta tcgttttttt aaaaaaaaag tttggtgttt ttaaccatgc tgttccagca
2281 aagatgatac cttaaactcc cactgcaagc ccatgaactt cccagagagt ggaacggctt
2341 gctcttcttt ctagaatgtc catgcacttg ggttttaatc agcagttccc tattattctg
2401 attttaagct gttcctgtga tgaacttaga gacagcatcg gtgtctgctg ctgtgtcccc
2461 aggtcttgtg tgggtggcac agatctgggc agttagatag tgctctgtgc ctaaggtgaa
2521 gccacactag ggtgaagcct cacttccctg tttgagcaat gcagtgcctg ctgcccgtgt
2581 gcatgaaggt acagccattc agataagtgg aactattgag ttacataaag aaaatagatt
2641 tgcatttgtc aggcagacgt ttatacaaca ccacggtgct tttatacatt gtgcttattt
2701 taataaaact gaaattctaa aaaaaaaaaa aaaaaa
//