LOCUS BC002681 2213 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens Rho guanine exchange factor (GEF) 16, mRNA (cDNA clone
MGC:3381 IMAGE:3613623), complete cds.
ACCESSION BC002681
VERSION BC002681.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2213)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2213)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: k Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15011976.
FEATURES Location/Qualifiers
source 1..2213
/db_xref="H-InvDB:HIT000031093"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3381 IMAGE:3613623"
/tissue_type="Uterus, endometrium adenocarcinoma"
/clone_lib="NIH_MGC_44"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2213
/gene="ARHGEF16"
/gene_synonym="GEF16"
/gene_synonym="NBR"
/db_xref="GeneID:27237"
/db_xref="HGNC:HGNC:15515"
CDS 400..1665
/gene="ARHGEF16"
/gene_synonym="GEF16"
/gene_synonym="NBR"
/codon_start=1
/product="Rho guanine exchange factor (GEF) 16"
/protein_id="AAH02681.1"
/db_xref="GeneID:27237"
/db_xref="HGNC:HGNC:15515"
/translation="MFEILTSEFSYQHSLSILVEEFLQSKELRATVTQMEHHHLFSNI
LDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKYFHPYIAYCSNEVYQQRTLQK
LISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRLPLLMDTLCLKTQGHSERY
KAASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRG
ELFLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYMVQDYAQMNHIQVEKIEP
SELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQW
QGLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDGWLYGERLRDGETGWFP
EDFARFITSRVAVEGNVRRMERLRVETDV"
BASE COUNT 491 a 669 c 692 g 361 t
ORIGIN
1 gcacgaggga agggcctggg gaagccaggt ggccagggag atgccatcca gctaagccct
61 aagctccagg ctctggctga ggaacccagc cagcctcata ctcggagccc ggccaaaaac
121 aagaagacgc tggggaggaa acgtgggcac aagggttcct tcaaggacga cccccagctc
181 taccaggaga tccaggagcg gggcctgaac accagccagg agtctgatga cgacatcctc
241 gatgagtcct ccagccccga gggaacccag aaggtggacg ccaccattgt ggtcaagagc
301 taccggcccg cccaggtcac ctggagccag ctcccggagg tggtggaatt gggcatcctg
361 gaccagctct ccactgagga gcggaaaagg caggaggcca tgttcgagat cctcacgtcg
421 gagttctcct accagcacag cctgagcatc ctggtggagg agttcctgca gtccaaggag
481 ctgcgggcga ccgtgaccca gatggagcac caccacctct tctccaacat cctggatgtc
541 ctgggtgcca gtcagaggtt cttcgaggac ctggagcagc ggcacaaggc ccaggtgctg
601 gtcgaggaca tcagtgacat cctggaggag cacgctgaga agtacttcca cccctacatc
661 gcctactgct ccaacgaggt ctaccaacag cgcacgctgc agaagctgat aagcagcaac
721 gccgccttcc gagaggccct gagagagatt gagaggcggc cggcgtgcgg gggcctgccc
781 atgctctcct tcctgatcct ccccatgcag cgggtgaccc ggctgcccct cctgatggat
841 acgctctgcc tcaagaccca gggccactcc gaaaggtaca aggctgccag ccgtgcactg
901 aaggccatca gcaagctggt gaggcagtgc aacgaggggg cccacaggat ggagcgcatg
961 gagcagatgt acacgctgca cacacagctg gacttcagca aggtcaagtc cctcccactg
1021 atctccgcct cccggtggct gctgaagcgc ggagagctgt tcttagtgga agaaaccgga
1081 ctttttcgaa aaattgccag ccggccaacg tgctaccttt tcctgttcaa cgatgtcctg
1141 gttgtgacca agaagaagag cgaggagagc tacatggtcc aggactacgc ccagatgaac
1201 cacatccagg tagagaagat agagccgtct gagctccctc tgcccggggg cggcaaccgt
1261 agctcctccg tgccccaccc cttccaggtg accctgcttc gcaacagcga gggccgccag
1321 gagcagctcc tgctctcctc ggactccgcg agtgaccggg cacggtggat cgtggcgctc
1381 acacacagtg agagacagtg gcagggcctc tccagcaaag gagacctgcc ccaggtggag
1441 atcaccaagg ccttcttcgc gaagcaagca gacgaggtca cactgcagca ggcggacgtg
1501 gtcctggttc tgcagcagga ggatgggtgg ctctatggcg agaggctccg ggacggagag
1561 acgggatggt tccccgagga ctttgcccgc ttcatcacca gccgtgtggc cgtggagggc
1621 aatgtccgca ggatggagcg tctgcgggtg gagacggacg tgtagccctg gcgaggccag
1681 ccggcggcag cacagcctgt ccccaatcag caagtggtcg tgcctggctc tagagagcgt
1741 ggggagctgg tctcaaggac ccagcatggt tccctggggc ttcccaagag cctgtggctg
1801 tggtgccggg ctccagacac ttcacggaag gaagatcaca tgtccccaga gaggcacccc
1861 caggcaagct cgagggggcc acaccgtgtc ccagggagcc cagcctattc ccgttggctg
1921 gctgggcccc tctcagctgc tgggccccac ctccccactg cacccagggg acaactccac
1981 ctggactgat gggcacagga ggcaccaata gcgattattg ggggcaatgc gaggtctcct
2041 cctatgccct tcctacccct gagtgggaca agaagggcct tgagtgccca ggagtgcccc
2101 acgttctgag aaggggccgg ccggagggag gggacccggc agggagattt cggttttgag
2161 gtttctaaat acattaaagt tatttcttaa gaaaaaaaaa aaaaaaaaaa aaa
//