LOCUS BC002631 2091 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens matrix metallopeptidase 28, mRNA (cDNA clone MGC:4164
IMAGE:3610296), complete cds.
ACCESSION BC002631
VERSION BC002631.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2091)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2091)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002631.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: a Column: 19
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..2091
/db_xref="H-InvDB:HIT000031049"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:4164 IMAGE:3610296"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2091
/gene="MMP28"
/gene_synonym="EPILYSIN"
/gene_synonym="MM28"
/gene_synonym="MMP-28"
/gene_synonym="MMP25"
/db_xref="GeneID:79148"
/db_xref="HGNC:HGNC:14366"
/db_xref="MIM:608417"
CDS 248..1429
/gene="MMP28"
/gene_synonym="EPILYSIN"
/gene_synonym="MM28"
/gene_synonym="MMP-28"
/gene_synonym="MMP25"
/codon_start=1
/product="MMP28 protein"
/protein_id="AAH02631.1"
/db_xref="GeneID:79148"
/db_xref="HGNC:HGNC:14366"
/db_xref="MIM:608417"
/translation="MVARVGLLLRALQLLLWGHLDAQPAERGGQELRKEAEAFLEKYG
YLNEQVPKAPTSTRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTDTNSYAAW
AERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPAVRGAVRAAFQ
LWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFLPRRGEAHF
DQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGRDALLSWDDV
LAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYCHSSFDAITVD
RQQQLYIFKGSHFWEVAADGNVSEPRPLQERWVGLPPNIEAAAVSLNDGDFYFFKVQS
V"
BASE COUNT 428 a 675 c 639 g 349 t
ORIGIN
1 cggggccggc ggacccgcgg gcaggcactg cccgggctgg acgacgtctg gccggctccc
61 ggcgaagggc agcggaggag cggcccagag cgcgcagcta gggcactggc gaaaccccgg
121 gacagtccct ctccgtgcgg gggcggcgca gagcagtccc atccccgggg tcccgggcgc
181 ggctgactgc cggctggttc cctgcgcgca gtagctcccc gagccgggct gcaccggagg
241 cggcgagatg gtcgcgcgcg tcggcctcct gctgcgcgcc ctgcagctgc tactgtgggg
301 ccacctggac gcccagcccg cggagcgcgg aggccaggag ctgcgcaagg aggcggaggc
361 attcctagag aagtacggat acctcaatga acaggtcccc aaagctccca cctccactcg
421 attcagcgat gccatcagag cgtttcagtg ggtgtcccag ctacctgtca gcggcgtgtt
481 ggaccgcgcc accctgcgcc agatgactcg tccccgctgc ggggttacag ataccaacag
541 ttatgcggcc tgggctgaga ggatcagtga cttgtttgct agacaccgga ccaaaatgag
601 gcgtaagaaa cgctttgcaa agcaaggtaa caaatggtac aagcagcacc tctcctaccg
661 cctggtgaac tggcctgagc atctgccgga gccggcagtt cggggcgccg tgcgcgccgc
721 cttccagttg tggagcaacg tctcagcgct ggagttctgg gaggccccag ccacaggccc
781 cgctgacatc cggctcacct tcttccaagg ggaccacaac gatgggctgg gcaatgcctt
841 tgatggccca gggggcgccc tggcgcacgc cttcctgccc cgccgcggcg aagcgcactt
901 cgaccaagat gagcgctggt ccctgagccg ccgccgcggg cgcaacctgt tcgtggtgct
961 ggcgcacgag atcggtcaca cgcttggcct cacccactcg cccgcgccgc gcgcgctcat
1021 ggcgccctac tacaagaggc tgggccgcga cgcgctgctc agctgggacg acgtgctggc
1081 cgtgcagagc ctgtatggga agcccctagg gggctcagtg gccgtccagc tcccaggaaa
1141 gctgttcact gactttgaga cctgggactc ctacagcccc caaggaaggc gccctgaaac
1201 gcagggccct aaatactgcc actcttcctt cgatgccatc actgtagaca ggcaacagca
1261 actgtacatt tttaaaggga gccatttctg ggaggtggca gctgatggca acgtctcaga
1321 gccccgtcca ctgcaggaaa gatgggtcgg gctgcccccc aacattgagg ctgcggcagt
1381 gtcattgaat gatggagatt tctacttctt caaagtgcaa tccgtttgat tgatatgaat
1441 accaaccatc gtgggctcca gcttaaagga gagcagaggg ggtcgatgct ggaggttccg
1501 gggccccaag ccagtgtggg gtctcccaca gctgtgccgg gcagggggcc tgccccgcca
1561 tcctgacgcc gccctcttct tccctcctct gcgccgcctc atcctcttca agggtgcccg
1621 ctactacgtg ctggcccgag ggggactgca agtggagccc tactaccccc gaagtctgca
1681 ggactgggga ggcatccctg aggaggtcag cggcgccctg ccgaggcccg atggctccat
1741 catcttcttc cgagatgacc gctactggcg cctcgaccag gccaaactgc aggcaaccac
1801 ctcgggccgc tgggccaccg agctgccctg gatgggctgc tggcatgcca actcggggag
1861 cgccctgttc tgaaggcacc tcctcacctc agaaactggt ggtgctctca gggcaaaatc
1921 atgttcccca cccccggggc agaacccctc ttagaagcct ctgagtccct ctgcagaaga
1981 ccgggcagca aagcctccat ctggaagtct gtctgccttt gttccttgaa aaaaaaaaaa
2041 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//