LOCUS BC002609 2177 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens chromobox homolog 1 (HP1 beta homolog Drosophila),
mRNA (cDNA clone MGC:1267 IMAGE:3140815), complete cds.
ACCESSION BC002609
VERSION BC002609.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2177)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2177)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: n Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21359877.
FEATURES Location/Qualifiers
source 1..2177
/db_xref="H-InvDB:HIT000031032"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1267 IMAGE:3140815"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_9"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2177
/gene="CBX1"
/gene_synonym="CBX"
/gene_synonym="HP1-BETA"
/gene_synonym="HP1Hs-beta"
/gene_synonym="M31"
/gene_synonym="MOD1"
/db_xref="GeneID:10951"
/db_xref="MIM:604511"
CDS 216..773
/gene="CBX1"
/gene_synonym="CBX"
/gene_synonym="HP1-BETA"
/gene_synonym="HP1Hs-beta"
/gene_synonym="M31"
/gene_synonym="MOD1"
/codon_start=1
/product="CBX1 protein"
/protein_id="AAH02609.1"
/db_xref="GeneID:10951"
/db_xref="MIM:604511"
/translation="MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKG
FSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKK
KKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVV
ISFYEERLTWHSYPSEDDDKKDDKN"
misc_feature 294..389
/gene="CBX1"
/gene_synonym="CBX"
/gene_synonym="HP1-BETA"
/gene_synonym="HP1Hs-beta"
/gene_synonym="M31"
/gene_synonym="MOD1"
/note="chromo; Region: 'chromo' (CHRromatin Organization
MOdifier) domain"
/db_xref="CDD:pfam00385"
misc_feature 558..731
/gene="CBX1"
/gene_synonym="CBX"
/gene_synonym="HP1-BETA"
/gene_synonym="HP1Hs-beta"
/gene_synonym="M31"
/gene_synonym="MOD1"
/note="Chromo_shadow; Region: Chromo shadow domain. This
domain is distantly related to pfam00385. This domain is
always found in association with a chromo domain"
/db_xref="CDD:pfam01393"
BASE COUNT 656 a 425 c 563 g 533 t
ORIGIN
1 tttgttcggc tgaggggagg gccgttggcc ggggcctgcg gtacgccgct tcagtgaggg
61 acgccactgc ggccacccgg cttgctgcct tcctgggcgc cactccccca ggcgacccga
121 cgcgacgcgc cagtagcgca gcaccgattc ctctcgggct cttgggcgct gctctgagca
181 gcgtcaccct ttacaccaga aagctggcgg gcactatggg gaaaaaacaa aacaagaaga
241 aagtggagga ggtgctagaa gaggaggaag aggaatatgt ggtggaaaaa gttctcgacc
301 gtcgagtggt aaagggcaaa gtggagtacc tcctaaagtg gaagggattc tcagatgagg
361 acaacacatg ggagccagaa gagaacctgg attgccccga cctcattgct gagtttctgc
421 agtcacagaa aacagcacat gagacagata aatcagaggg aggcaagcgc aaagctgatt
481 ctgattctga agataaggga gaggagagca aaccaaagaa gaagaaagaa gagtcagaaa
541 agccacgagg ctttgctcga ggtttggagc cggagcggat tattggagct acagactcca
601 gtggagagct catgttcctg atgaaatgga aaaactctga tgaggctgac ctggtccctg
661 ccaaggaagc caatgtcaag tgcccacagg ttgtcatatc cttctatgag gaaaggctga
721 cgtggcattc ctacccctcg gaggatgatg acaaaaaaga tgacaagaac taacgctcct
781 gagtaccagc ccctgtcaca tctgactgtg ggtttcaagt gggaagggaa ggagttctac
841 ttgtcttgac accatagagg tggcttgaga agatgtcctt tgaagagcca gtatagtttc
901 tgtgccctgc agcagcccaa gtgctttaaa gccgtttcaa gctgtatagt ttgcacaccc
961 atcccagtgg aggggaaagg ggataagtgt ttcaaggcaa ccttttctgc actttgctgc
1021 gaaaagcaaa gggccttcta tgaaggacaa aacttgcaga attgggtgtg tgggagagca
1081 aaaaaatact gtagatcttc aaagagcatc tccacaaccc acagccttct tcccaatagt
1141 gttaactctg catttttaca gcgtagcatg tgtgtagttt ttggctatta ctggtgtatt
1201 atttggggga gggagggatg gggaggggag aaagggagat gggtagcatc attttgatta
1261 acatttgggg cctgataggg gaaatggtga agcaatggaa aagaacagac aactaatgat
1321 ttgcttctat gtccagaata ttttaccttt aaaaaaatgt cattggcacc ataaataagg
1381 actgtgagag actgtttaaa agctgtgaaa gtctaaaacc tataagccaa ggtgttccct
1441 gcctaaactt attgctgttc ccacaaagga ctaagcctgt tcataagtta ccaaagttgc
1501 cattttggag atggaaattg acgaggaggg aaggtctttt attggagagt atacagtaca
1561 agcagatcat tctgccttag aggtgctaat tcccgaaatt agaagaccct ttcttttcca
1621 gtaacgaagt tataaatatc agcttgttca tccaagccac tggctgaggt gttaggaaga
1681 ggaagagggt ggtagaggag gtaagacagt agggaaagac aagggcccat gctcttagtg
1741 gggaaaactc ttggagccgt ttactttgag ctttgaacac tgaaaccatt gttggcaggg
1801 ttcagtcact gacagcacaa gtttcactga attgatccaa gagtttagtg atttcaaaag
1861 ccttggtctc aggagaagat taaactttca tattgggcag tggttcactt taaaacacac
1921 acatacacac acaaaacaat tttttaagaa atcctaataa gtaacatacc caaaatgctc
1981 tgtcttgagt catgagaacc atcagttctt gatattgtct agacttgcat ctagagctac
2041 gttgtaaaat tcttttaggc atgtgttaga tttctgtgta aactttgttt aaatgtaaac
2101 ttcatactac attgtcagtt tttgtcttaa taaaactata gatttataat ccctgaaaaa
2161 aaaaaaaaaa aaaaaaa
//