LOCUS BC002578 1670 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens major histocompatibility complex, class I, E, mRNA
(cDNA clone MGC:1408 IMAGE:3140835), complete cds.
ACCESSION BC002578
VERSION BC002578.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1670)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1670)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC002578.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: d Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62912478.
FEATURES Location/Qualifiers
source 1..1670
/db_xref="H-InvDB:HIT000031006_06"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1408 IMAGE:3140835"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_9"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1670
/gene="HLA-E"
/gene_synonym="EA1.2"
/gene_synonym="EA2.1"
/gene_synonym="HLA-6.2"
/gene_synonym="MHC"
/db_xref="GeneID:3133"
/db_xref="HGNC:HGNC:4962"
/db_xref="MIM:143010"
CDS 15..1091
/gene="HLA-E"
/gene_synonym="EA1.2"
/gene_synonym="EA2.1"
/gene_synonym="HLA-6.2"
/gene_synonym="MHC"
/codon_start=1
/product="major histocompatibility complex, class I, E"
/protein_id="AAH02578.1"
/db_xref="GeneID:3133"
/db_xref="HGNC:HGNC:4962"
/db_xref="MIM:143010"
/translation="MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFI
SVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTL
RGYYNQSEAGSHTLQWMHGCELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTA
AQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDH
EATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQ
RYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSS
GGKGGSYSKAEWSDSAQGSESHSL"
BASE COUNT 377 a 464 c 509 g 320 t
ORIGIN
1 cagaggctgg gatcatggta gatggaaccc tccttttact cctctcggag gccctggccc
61 ttacccagac ctgggcgggc tcccactcct tgaagtattt ccacacttcc gtgtcccggc
121 ccggccgcgg ggagccccgc ttcatctctg tgggctacgt ggacgacacc cagttcgtgc
181 gcttcgacaa cgacgccgcg agtccgagga tggtgccgcg ggcgccgtgg atggagcagg
241 aggggtcaga gtattgggac cgggagacac ggagcgccag ggacaccgca cagattttcc
301 gagtgaacct gcggacgctg cgcggctact acaatcagag cgaggccggg tctcacaccc
361 tgcagtggat gcatggctgc gagctggggc ccgacaggcg cttcctccgc gggtatgaac
421 agttcgccta cgacggcaag gattatctca ccctgaatga ggacctgcgc tcctggaccg
481 cggtggacac ggcggctcag atctccgagc aaaagtcaaa tgatgcctct gaggcggagc
541 accagagagc ctacctggaa gacacatgcg tggagtggct ccacaaatac ctggagaagg
601 ggaaggagac gctgcttcac ctggagcccc caaagacaca cgtgactcac caccccatct
661 ctgaccatga ggccaccctg aggtgctggg ccctgggctt ctaccctgcg gagatcacac
721 tgacctggca gcaggatggg gagggccata cccaggacac ggagctcgtg gagaccaggc
781 ctgcagggga tggaaccttc cagaagtggg cagctgtggt ggtgccttct ggagaggagc
841 agagatacac gtgccatgtg cagcatgagg ggctacccga gcccgtcacc ctgagatgga
901 agccggcttc ccagcccacc atccccatcg tgggcatcat tgctggcctg gttctccttg
961 gatctgtggt ctctggagct gtggttgctg ctgtgatatg gaggaagaag agctcaggtg
1021 gaaaaggagg gagctactct aaggctgagt ggagcgacag tgcccagggg tctgagtctc
1081 acagcttgta aagcctgaga cagctgcctt gtgtgcgact gagatgcaca gctgccttgt
1141 gtgcgactga gatgcaggat ttcctcacgc ctcccctatg tgtcttaggg gactctggct
1201 tctctttttg caagggcctc tgaatctgtc tgtgtccctg ttagcacaat gtgaggaggt
1261 agagaaacag tccacctctg tgtctaccat gacccccttc ctcacactga cctgtgttcc
1321 ttccctgttc tcttttctat taaaaataag aacctgggca gagtgcggca gctcatgcct
1381 gtaatcccag cacttaggga ggccgaggag ggcagatcac gaggtcagga gatcgaaacc
1441 atcctggcta acacggtgaa accccgtctc tactaaaaaa tacaaaaaat tagctgggcg
1501 cagaggcacg ggcctgtagt cccagctact caggaggcgg aggcaggaga atggcgtcaa
1561 cccgggaggc ggaggttgca gtgagccagg attgtgcgac tgcactccag cctgggtgac
1621 agggtgaaac gccatctcaa aaaataaaaa ttaaaaaaaa aaaaaaaaaa
//