LOCUS BC002573 1330 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens uroporphyrinogen III synthase, mRNA (cDNA clone
MGC:1550 IMAGE:3160463), complete cds.
ACCESSION BC002573
VERSION BC002573.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1330)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1330)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002573.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: b Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557872.
FEATURES Location/Qualifiers
source 1..1330
/db_xref="H-InvDB:HIT000031002"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1550 IMAGE:3160463"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1330
/gene="UROS"
/db_xref="GeneID:7390"
/db_xref="HGNC:HGNC:12592"
/db_xref="MIM:606938"
CDS 226..1023
/gene="UROS"
/codon_start=1
/product="uroporphyrinogen III synthase"
/protein_id="AAH02573.1"
/db_xref="GeneID:7390"
/db_xref="HGNC:HGNC:12592"
/db_xref="MIM:606938"
/translation="MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLP
SFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNA
TASLVSKIGLDTEGETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGI
AMESITVYQTVAHPGIQGNLNSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQ
IKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC"
BASE COUNT 314 a 365 c 367 g 284 t
ORIGIN
1 cccacgcgac cccagtctga ggtgcggggt cctggggccc ggcgcgggtg gccgccgcgg
61 cccctcgggc tgcgtgggga gggggcttcc gcccctgttg tcattgctcc tgcagccttt
121 tcgctgggac tgcgcgacac cgccccccga ccgggtgccc gctgtgtgcc aggccgggtg
181 ctgggcacgg tcccgcgagt gccctataag gactgccagg caataatgaa ggttctttta
241 ctgaaggatg cgaaggaaga tgactgtggc caggatccgt atatcaggga attaggatta
301 tatggacttg aagccacttt gatccctgtt ttatcgtttg agtttttgtc tcttcccagt
361 ttctctgaga agctttctca tcctgaagat tacgggggac tcatttttac cagccccaga
421 gcagtggaag cagcagagtt atgtttggag caaaacaata aaactgaagt ctgggaaagg
481 tctctgaaag aaaaatggaa tgccaagtca gtgtatgtgg ttggaaatgc tactgcttct
541 ctagtgagta aaattggcct ggatacagaa ggagaaacct gtggaaatgc agaaaagctt
601 gcagaatata tttgttccag ggagtcctca gcactgcctc ttctatttcc ctgtggaaac
661 ctcaaaagag aaatcctgcc aaaagcgctc aaggacaaag ggattgccat ggaaagcata
721 actgtgtatc agacagttgc acacccagga atccaaggga acctgaacag ctactattcc
781 cagcaggggg ttccagccag catcacattt tttagtccct ctggcctcac atacagtctc
841 aagcacattc aggagttatc tggtgacaat atcgatcaaa ttaagtttgc agccatcggc
901 cccactacgg ctcgcgcgct ggccgcccag ggccttcctg taagctgcac tgcagagagc
961 cccacgccac aagccctggc cactggcatc aggaaggctc tccagcccca tggctgctgc
1021 tgagtcagcc acctagcgct ggccccatgc agcctccctg ggctgggctg gctctggatg
1081 gagccaggca tcggcaaggg ctctcgggag ctgctgccgt cagactcctg cctcaagcct
1141 gagtggaagc acctgaggac cggggatcgg gacctgacct ggggctggcc tcaggcccac
1201 gtgcacgtga ctgccctctg tggaagccag cttaaaccct agccctgtga gagcttcctg
1261 tgcccagcag gaaggaagtc aaataaacca cactgactac ctgtgcttac tgaaaaaaaa
1321 aaaaaaaaaa
//