LOCUS BC002513 2983 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2, subunit 1
alpha, 35kDa, mRNA (cDNA clone MGC:1511 IMAGE:3139624), complete
cds.
ACCESSION BC002513
VERSION BC002513.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2983)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2983)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002513.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: a Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34147492.
FEATURES Location/Qualifiers
source 1..2983
/db_xref="H-InvDB:HIT000030955"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1511 IMAGE:3139624"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2983
/gene="EIF2S1"
/gene_synonym="EIF-2"
/gene_synonym="EIF-2A"
/gene_synonym="EIF-2alpha"
/gene_synonym="EIF2A"
/db_xref="GeneID:1965"
/db_xref="HGNC:HGNC:3265"
/db_xref="MIM:603907"
CDS 91..1038
/gene="EIF2S1"
/gene_synonym="EIF-2"
/gene_synonym="EIF-2A"
/gene_synonym="EIF-2alpha"
/gene_synonym="EIF2A"
/codon_start=1
/product="EIF2S1 protein"
/protein_id="AAH02513.1"
/db_xref="GeneID:1965"
/db_xref="HGNC:HGNC:3265"
/db_xref="MIM:603907"
/translation="MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEG
MILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKF
TKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDP
SILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNC
STENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPK
VVTDTDETELARQMERLERENAEVDGDDDAEEMEAKAED"
BASE COUNT 945 a 518 c 632 g 888 t
ORIGIN
1 ggcggccggt gagggggaag caagtctggt ctctgtgatt gaagaagtcg gctctgggct
61 ccagtgcggg aatcacacac atacctcaga atgccgggtc taagttgtag attttatcaa
121 cacaaatttc ctgaggtgga agatgtagtg atggtgaatg tcagatccat tgctgaaatg
181 ggggcttatg tcagcttgct ggaatacaac aacattgaag gcatgattct tcttagtgaa
241 ttatccagaa ggcgtatccg ttctatcaac aaactcatcc gaattggcag gaatgagtgt
301 gtggttgtca ttagggtgga caaagaaaaa ggatatattg atttgtcaaa aagaagagtt
361 tctccagagg aagcaatcaa atgtgaagac aaattcacaa aatccaaaac tgtttatagc
421 attcttcgtc atgttgctga ggtgttagaa tacaccaagg atgagcagct ggaaagccta
481 ttccagagga ctgcctgggt ctttgatgac aagtacaaga gacctggata tggtgcctat
541 gatgcattta agcatgcagt ctcagaccca tctattttgg atagtttaga tttgaatgaa
601 gatgaacggg aagtactcat taataatatt aataggcgct tgaccccaca ggctgtcaaa
661 attcgagcag atattgaagt ggcttgttat ggttatgaag gcattgatgc tgtaaaagaa
721 gccctaagag caggtttgaa ttgttctaca gaaaacatgc ccattaagat taatctaata
781 gctcctcctc ggtatgtaat gactacgaca accctggaga gaacagaagg cctttctgtc
841 ctcagtcaag ctatggctgt tatcaaagag aagattgagg aaaagagggg tgtgttcaat
901 gttcaaatgg agcccaaagt ggtcacagat acagatgaga ctgaacttgc gaggcagatg
961 gagaggcttg aaagagaaaa tgccgaagtg gatggagatg atgatgcaga agaaatggaa
1021 gccaaagctg aagattaact ttgtgggaaa cagagtccaa tttaaggaac acagagcagc
1081 gcttcctggc tgtaaatcct agacttgaaa gttttccagt attgaaaact tcaaagctga
1141 atatttttta tttctaagta tttaaatgtt ctaacagatc agaacatgaa atgccctcct
1201 aaatgtcagc tgttgtcaca cagtagctcc aacactttga gcatttttaa gggagtggcc
1261 tcatttcact agagacaaat ctttaagaat agttctaaaa ttgggcttgt gatttccatt
1321 tctgatgtct ccagattggc acccctttct agttcaatgc ctcacgagat ttgccagggg
1381 catccaaggc aaacaatccc aatctttcta tataaaatgt attcaagcaa acatcaaata
1441 aatttctggg atatttaact ataggcttct tccttcttgt caccagttaa aagcatttta
1501 atactaagac cctaattctt ttatctttat tttagtcttg atgtggaact gtaggagcag
1561 gtgaataaag gatctctata acagatcctt tcaaaagaag agttttagag aaaataaatt
1621 taactttaac cacagtgaaa gttgaccctt agcgggacaa agccttaaaa tgcattgaaa
1681 gaattagatc ggttctgtgc cttttatcta tttgagattg atgacaacct gtgtgagaga
1741 atttatcaca ccacgtcctt attggaataa taagctactt gccttgagtt tataattcag
1801 ggtggtaaag tatgttttta aattttaaaa agcagctgca ttttttattt agttggaata
1861 tcacccaatt ttttattttt attgctatta aaatatccac tagatgccac ctagagctcc
1921 agttctttat aacaaaacag ggatctgttt gaacacttac tgttgttttt ttttttttac
1981 atgtttccat catttctgtc tttaagaact aattcgtaca taataagttt cataggtaac
2041 acattatatt ctcttatgat acttgaggta ccagttgtat ttaattttat tcattatccc
2101 tagatagcta ttaagatact tagattagac ctaacccacc atagtcaatc caagactaga
2161 ctactcaata ttaaagggtc tggaaaatag aagagtgtgt tgggcaggta gtttgtacca
2221 tttatgaagg tttgttcctt tgttaaattt agcagcctgt actagctttt gaaatccaga
2281 agttttaact tccagtggct ggtttctgag agagtgccat gattgctagc cagcattcca
2341 tattgggaat atgtagagga gaacctggat gtacttaaga gtggcatata attttcactt
2401 ctgtctgttg aggcaaaaaa aaaacaagtt tagaaagctg gcaacatgaa gaatgcattc
2461 aaaatataac aggtgcttct ttgttgtacg cagaggaatt ttttcttttg attttgttta
2521 ctgaaatttg ttatacttca aaagccataa cttgaaaaat actggtggcg tcgatggtga
2581 gtgattttta tcccacgtgg gccttttgct cagttccatg gcaattttgt aaattgaccc
2641 tagccagaga atagatcagt atttcactga taccacgagg aaaagaacaa acaaaactta
2701 aaagtattca tacaccttgc taacctaaaa gacagcaggg acaagataca tatgaggaca
2761 aggtatacac ccagttctga ataacttgaa gaacaggctt ggcaaagaag taagtttatc
2821 caaatcttga atttctgcca ggcatggtag ctcatgcctg taaccctggc acttaagggg
2881 ccaaggcagg aggatcactt gaggccagtg agctgtgatc actccagtgc actcgagcct
2941 gggtgacagg gcaagaccct gtctcaaaaa aaaaaaaaaa aaa
//