LOCUS BC002452 1940 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens caspase 9, apoptosis-related cysteine peptidase, mRNA
(cDNA clone MGC:3054 IMAGE:3343958), complete cds.
ACCESSION BC002452
VERSION BC002452.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1940)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1940)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 28, 2003 this sequence version replaced BC002452.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: d Column: 9.
FEATURES Location/Qualifiers
source 1..1940
/db_xref="H-InvDB:HIT000030903"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3054 IMAGE:3343958"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1940
/gene="CASP9"
/gene_synonym="APAF-3"
/gene_synonym="APAF3"
/gene_synonym="CASPASE-9c"
/gene_synonym="ICE-LAP6"
/gene_synonym="MCH6"
/db_xref="GeneID:842"
/db_xref="HGNC:HGNC:1511"
/db_xref="MIM:602234"
CDS 7..1257
/gene="CASP9"
/gene_synonym="APAF-3"
/gene_synonym="APAF3"
/gene_synonym="CASPASE-9c"
/gene_synonym="ICE-LAP6"
/gene_synonym="MCH6"
/codon_start=1
/product="caspase 9, apoptosis-related cysteine peptidase"
/protein_id="AAH02452.1"
/db_xref="GeneID:842"
/db_xref="HGNC:HGNC:1511"
/db_xref="MIM:602234"
/translation="MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQ
RAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPT
LENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPC
GHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLE
LAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLG
GKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISS
LPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVS
VKGIYKQMPGCFNFLRKKLFFKTS"
BASE COUNT 440 a 507 c 527 g 466 t
ORIGIN
1 ctcgccatgg acgaagcgga tcggcggctc ctgcggcggt gccggctgcg gctggtggaa
61 gagctgcagg tggaccagct ctgggacgcc ctgctgagcc gcgagctgtt caggccccat
121 atgatcgagg acatccagcg ggcaggctct ggatctcggc gggatcaggc caggcagctg
181 atcatagatc tggagactcg agggagtcag gctcttcctt tgttcatctc ctgcttagag
241 gacacaggcc aggacatgct ggcttcgttt ctgcgaacta acaggcaagc agcaaagttg
301 tcgaagccaa ccctagaaaa ccttacccca gtggtgctca gaccagagat tcgcaaacca
361 gaggttctca gaccggaaac acccagacca gtggacattg gttctggagg atttggtgat
421 gtcggtgctc ttgagagttt gaggggaaat gcagatttgg cttacatcct gagcatggag
481 ccctgtggcc actgcctcat tatcaacaat gtgaacttct gccgtgagtc cgggctccgc
541 acccgcactg gctccaacat cgactgtgag aagttgcggc gtcgcttctc ctcgctgcat
601 ttcatggtgg aggtgaaggg cgacctgact gccaagaaaa tggtgctggc tttgctggag
661 ctggcgcagc aggaccacgg tgctctggac tgctgcgtgg tggtcattct ctctcacggc
721 tgtcaggcca gccacctgca gttcccaggg gctgtctacg gcacagatgg atgccctgtg
781 tcggtcgaga agattgtgaa catcttcaat gggaccagct gccccagcct gggagggaag
841 cccaagctct ttttcatcca ggcctgtggt ggggagcaga aagaccatgg gtttgaggtg
901 gcctccactt cccctgaaga cgagtcccct ggcagtaacc ccgagccaga tgccaccccg
961 ttccaggaag gtttgaggac cttcgaccag ctggacgcca tatctagttt gcccacaccc
1021 agtgacatct ttgtgtccta ctctactttc ccaggttttg tttcctggag ggaccccaag
1081 agtggctcct ggtacgttga gaccctggac gacatctttg agcagtgggc tcactctgaa
1141 gacctgcagt ccctcctgct tagggtcgct aatgctgttt cggtgaaagg gatttataaa
1201 cagatgcctg gttgctttaa tttcctccgg aaaaaacttt tctttaaaac atcataaggc
1261 cagggcccct caccctgcct tatcttgcac cccaaagctt tcctgcccca ggcctgaaag
1321 aggctgaggc ctggactttc ctgcaactca aggactttgc agccggcaca gggtctgctc
1381 tttctctgcc agtgacagac aggctcttag cagcttccag attgacgaca agtgctgaac
1441 agtggaggaa gagggacaga tgaatgccgt ggattgcacg tggcctcttg agcagtggct
1501 ggtccagggc tagtgacttg tgtcccatga tccctgtgtt gtctctagag cagggattaa
1561 cctctgcact actgacatgt ggggccaggt caccctttgc tgtgaggctg tcctgtacat
1621 tgtgggatgt tcagcactgt cccttgcctc aatgccagta acgcgtcttc ctgagtggtg
1681 ccaaacaaaa aggttctcag gtgttgccaa atatgtcctg gggtataaaa ctttcctcgc
1741 ctgacaacca ctggtctgta gggatttttg gctacacaca aaccagtatc gctcatagat
1801 cagcaaaccg gggcctacta gagtctgaac agctgtaatc tatgaattct aagtgaaatt
1861 ttaaaaattg ttaatttttc ctatattgca ttaattttaa aaaataaatc tgaggcaaat
1921 aaaaaaaaaa aaaaaaaaaa
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