LOCUS BC002398 1308 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens nucleophosmin (nucleolar phosphoprotein B23,
numatrin), mRNA (cDNA clone MGC:8463 IMAGE:2821577), complete cds.
ACCESSION BC002398
VERSION BC002398.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1308)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1308)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002398.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: f Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40353733.
FEATURES Location/Qualifiers
source 1..1308
/db_xref="H-InvDB:HIT000030861"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8463 IMAGE:2821577"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1308
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
CDS 88..972
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/codon_start=1
/product="nucleophosmin (nucleolar phosphoprotein B23,
numatrin)"
/protein_id="AAH02398.1"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
/translation="MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSL
RTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRL
KCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAA
DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSS
TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCF
RMTDQEAIQDLWQWRKSL"
BASE COUNT 440 a 222 c 309 g 337 t
ORIGIN
1 gattccgtcc tgcgcggttg ttctctggag cagcgttctt ttatctccgt ccgccttctc
61 tcctacctaa gtgcgtgccg ccacccgatg gaagattcga tggacatgga catgagcccc
121 ctgaggcccc agaactatct tttcggttgt gaactaaagg ccgacaaaga ttatcacttt
181 aaggtggata atgatgaaaa tgagcaccag ttatctttaa gaacggtcag tttaggggct
241 ggtgcaaagg atgagttgca cattgttgaa gcagaggcaa tgaattacga aggcagtcca
301 attaaagtaa cactggcaac tttgaaaatg tctgtacagc caacggtttc ccttgggggc
361 tttgaaataa caccaccagt ggtcttaagg ttgaagtgtg gttcagggcc agtgcatatt
421 agtggacagc acttagtagc tgtggaggaa gatgcagagt cagaagatga agaggaggag
481 gatgtgaaac tcttaagtat atctggaaag cggtctgccc ctggaggtgg tagcaaggtt
541 ccacagaaaa aagtaaaact tgctgctgat gaagatgatg acgatgatga tgaagaggat
601 gatgatgaag atgatgatga tgatgatttt gatgatgagg aagctgaaga aaaagcgcca
661 gtgaagaaat ctatacgaga tactccagcc aaaaatgcac aaaagtcaaa tcagaatgga
721 aaagactcaa aaccatcatc aacaccaaga tcaaaaggac aagaatcctt caagaaacag
781 gaaaaaactc ctaaaacacc aaaaggacct agttctgtag aagacattaa agcaaaaatg
841 caagcaagta tagaaaaagg tggttctctt cccaaagtgg aagccaaatt catcaattat
901 gtgaagaatt gcttccggat gactgaccaa gaggctattc aagatctctg gcagtggagg
961 aagtctcttt aagaaaatag tttaaacaat ttgttaaaaa attttccgtc ttatttcatt
1021 tctgtaacag ttgatatctg gctgtccttt ttataatgca gagtgagaac tttccctacc
1081 gtgtttgata aatgttgtcc aggttctatt gccaagaatg tgttgtccaa aatgcctgtt
1141 tagtttttaa agatggaact ccaccctttg cttggtttta agtatgtatg gaatgttatg
1201 ataggacata gtagtagcgg tggtcagaca tggaaatggt ggggagacaa aaatatacat
1261 gtgaaataaa actcagtatt ttaataaagt aaaaaaaaaa aaaaaaaa
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