LOCUS BC002357 1741 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens protoporphyrinogen oxidase, mRNA (cDNA clone MGC:8485
IMAGE:2821983), complete cds.
ACCESSION BC002357
VERSION BC002357.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1741)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1741)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002357.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: g Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45439340.
FEATURES Location/Qualifiers
source 1..1741
/db_xref="H-InvDB:HIT000030824"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8485 IMAGE:2821983"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1741
/gene="PPOX"
/gene_synonym="MGC8485"
/gene_synonym="PPO"
/gene_synonym="V290M"
/db_xref="GeneID:5498"
/db_xref="HGNC:HGNC:9280"
/db_xref="MIM:600923"
CDS 211..1644
/gene="PPOX"
/gene_synonym="MGC8485"
/gene_synonym="PPO"
/gene_synonym="V290M"
/codon_start=1
/product="protoporphyrinogen oxidase"
/protein_id="AAH02357.1"
/db_xref="GeneID:5498"
/db_xref="HGNC:HGNC:9280"
/db_xref="MIM:600923"
/translation="MGRTVVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIR
SVRGPNGAIFELGPRGIRPAGALGARTLLLVSELGLDSEVLPVRGDHPAAQNRFLYVG
GALHALPTGLRGLLRPSPPFSKPLFWAGLRELTKPRGKEPDETVHSFAQRRLGPEVAS
LAMDSLCRGVFAGNSRELSIRSCFPSLFQAEQTHRSILLGLLLGAGRTPQPDSALIRQ
ALAERWSQWSLRGGLEMLPQALETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSS
LEADHVISAIPASVLSELLPAEAAPLARALSAITAVSVAVVNLQYQGAHLPVQGFGHL
VPSSEDPGVLGIVYDSVAFPEQDGSPPGLRVTVMLGGSWLQTLEASGCVLSQELFQQR
AQEAAATQLGLKEMPSHCLVHLHKNCIPQYTLGHWQKLESARQFLTAHRLPLTLAGAS
YEGVAVNDCIESGRQAAVSVLGTEPNS"
BASE COUNT 379 a 478 c 525 g 359 t
ORIGIN
1 gccgcgagaa cagagtggac ggagcgtagg agagaccgaa aaggctgggg gtgggagtag
61 cggatttgaa gcacttgttg gcctacagag gtgtggcaag cagagcacct cagaactcag
121 gcgtactgcc cgccgcccga gccctgcgag ggccgatagc gagggtgtgg cccttatctg
181 cacccagcag agcgccggcg gggtttccgc atgggccgga ccgtggtcgt gctgggcgga
241 ggcatcagcg gcttggccgc cagttaccac ctgagccggg ccccctgccc ccctaaggtg
301 gtcctagtgg agagcagtga gcgtctggga ggctggattc gctccgttcg aggccctaat
361 ggtgctatct ttgagcttgg acctcgggga attaggccag cgggagccct aggggcccgg
421 accttgctcc tggtttctga gcttggcttg gattcagaag tgctgcctgt ccggggagac
481 cacccagctg cccagaacag gttcctctac gtgggcggtg ccctgcatgc cctacccact
541 ggcctcaggg ggctactccg cccttcaccc cccttctcca aacctctgtt ttgggctggg
601 ctgagggagc tgaccaagcc ccggggcaaa gagcctgatg agactgtgca cagttttgcc
661 cagcgccgcc ttggacctga ggtggcgtct ctagccatgg acagtctctg ccgtggagtg
721 tttgcaggca acagccgtga gctcagcatc aggtcctgct ttcccagtct cttccaagct
781 gagcaaaccc atcgttccat attactgggc ctgctgctgg gggcagggcg gaccccacag
841 ccagactcag cactcattcg ccaggccttg gctgagcgct ggagccagtg gtcacttcgt
901 ggaggtctag agatgttgcc tcaggccctt gaaacccacc tgactagtag gggggtcagt
961 gttctcagag gccagccggt ctgtgggctc agcctccagg cagaagggcg ctggaaggta
1021 tctctaaggg acagcagtct ggaggctgac cacgttatta gtgccattcc agcttcagtg
1081 ctcagtgagc tgctccctgc tgaggctgcc cctctggctc gtgccctgag tgccatcact
1141 gcagtgtctg tagctgtggt gaatctgcag taccaaggag cccatctgcc tgtccaggga
1201 tttggacatt tggtgccatc ttcagaagat ccaggagtcc tgggaatcgt gtatgactca
1261 gttgctttcc ctgagcagga cgggagcccc cctggcctca gagtgactgt gatgctggga
1321 ggttcctggt tacagacact ggaggctagt ggctgtgtct tatctcagga gctgtttcaa
1381 cagcgggccc aggaagcagc tgctacacaa ttaggactga aggagatgcc gagccactgc
1441 ttggtccatc tacacaagaa ctgcattccc cagtatacac taggtcactg gcaaaaacta
1501 gagtcagcta ggcaattcct gactgctcac aggttgcccc tgactctggc tggagcctcc
1561 tatgagggag ttgctgttaa tgactgtata gagagtgggc gccaggcagc agtcagtgtc
1621 ctgggcacag aacctaacag ctgatcccca actctcattc atgaaaataa aaattgctgg
1681 agcttggaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1741 a
//