LOCUS BC001917 1244 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens malate dehydrogenase 2, NAD (mitochondrial), mRNA
(cDNA clone MGC:3559 IMAGE:2823443), complete cds.
ACCESSION BC001917
VERSION BC001917.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1244)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1244)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-JAN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 9 Row: k Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21735620.
FEATURES Location/Qualifiers
source 1..1244
/db_xref="H-InvDB:HIT000030745"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3559 IMAGE:2823443"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1244
/gene="MDH2"
/gene_synonym="M-MDH"
/gene_synonym="MDH"
/gene_synonym="MGC:3559"
/gene_synonym="MOR1"
/db_xref="GeneID:4191"
/db_xref="HGNC:HGNC:6971"
/db_xref="MIM:154100"
CDS 29..1045
/gene="MDH2"
/gene_synonym="M-MDH"
/gene_synonym="MDH"
/gene_synonym="MGC:3559"
/gene_synonym="MOR1"
/codon_start=1
/product="malate dehydrogenase 2, NAD (mitochondrial)"
/protein_id="AAH01917.1"
/db_xref="GeneID:4191"
/db_xref="HGNC:HGNC:6971"
/db_xref="MIM:154100"
/translation="MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLL
KNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGV
PRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGV
YNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDF
PQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECS
FVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFV
KTLK"
BASE COUNT 292 a 359 c 321 g 272 t
ORIGIN
1 gccagtcggt gcccctcccg ctccagccat gctctccgcc ctcgcccggc ctgtcagcgc
61 tgctctccgc cgcagcttca gcacctcggc ccagaacaat gctaaagtag ctgtgctagg
121 ggcctctgga ggcatcgggc agccactttc acttctcctg aagaacagcc ccttggtgag
181 ccgcctgacc ctctatgata tcgcgcacac acccggagtg gccgcagatc tgagccacat
241 cgagaccaaa gccgctgtga aaggctacct cggacctgaa cagctgcctg actgcctgaa
301 aggttgtgat gtggtagtta ttccggctgg agtccccaga aagccaggca tgacccggga
361 cgacctgttc aacaccaatg ccacgattgt ggccaccctg accgctgcct gtgcccagca
421 ctgcccggaa gccatgatct gcgtcattgc caatccggtt aattccacca tccccatcac
481 agcagaagtt ttcaagaagc atggagtgta caaccccaac aaaatcttcg gcgtgacgac
541 cctggacatc gtcagagcca acacctttgt tgcagagctg aagggtttgg atccagctcg
601 agtcaacgtc cctgtcattg gtggccatgc tgggaagacc atcatccccc tgatctctca
661 gtgcaccccc aaggtggact ttccccagga ccagctgaca gcactcactg ggcggatcca
721 ggaggccggc acggaggtgg tcaaggctaa agccggagca ggctctgcca ccctctccat
781 ggcgtatgcc ggcgcccgct ttgtcttctc ccttgtggat gcaatgaatg gaaaggaagg
841 tgttgtggaa tgttccttcg ttaagtcaca ggaaacggaa tgtacctact tctccacacc
901 gctgctgctt gggaaaaagg gcatcgagaa gaacctgggc atcggcaaag tctcctcttt
961 tgaggagaag atgatctcgg atgccatccc cgagctgaag gcctccatca agaaggggga
1021 agatttcgtg aagaccctga agtgagccgc tgtgacgggt ggccagtttc cttaatttat
1081 gaaggcatca tgtcactgca aagccgttgc agataaactt tgtattttaa tttgctttgg
1141 tgatgattac tgtattgaca tcatcatgcc ttccaaattg tgggtggctc tgtgggcgca
1201 tcaataaaag ccgtccttga ttttaaaaaa aaaaaaaaaa aaaa
//