LOCUS BC001718 2382 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens v-crk sarcoma virus CT10 oncogene homolog (avian),
mRNA (cDNA clone MGC:3138 IMAGE:3353237), complete cds.
ACCESSION BC001718
VERSION BC001718.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2382)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2382)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-JAN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: h Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41327709.
FEATURES Location/Qualifiers
source 1..2382
/db_xref="H-InvDB:HIT000258884"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3138 IMAGE:3353237"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2382
/gene="CRK"
/gene_synonym="CRKII"
/db_xref="GeneID:1398"
/db_xref="HGNC:HGNC:2362"
/db_xref="MIM:164762"
CDS 103..1017
/gene="CRK"
/gene_synonym="CRKII"
/codon_start=1
/product="v-crk sarcoma virus CT10 oncogene homolog
(avian)"
/protein_id="AAH01718.1"
/db_xref="GeneID:1398"
/db_xref="HGNC:HGNC:2362"
/db_xref="MIM:164762"
/translation="MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSP
GDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLE
FYKIHYLDTTTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILR
IRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEP
GPYAQPSVNTPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWE
GECNGKRGHFPFTHVRLLDQQNPDEDFS"
BASE COUNT 588 a 568 c 650 g 576 t
ORIGIN
1 ctgtgaagct gaaaccggag ccggtccgct gggcggcggg cgccgggggc cggaggggcg
61 cgcgcggcgg cggcacccca gcgtttaggc gcggaggcag ccatggcggg caacttcgac
121 tcggaggagc ggagtagctg gtactggggg cggttgagtc ggcaggaggc ggtggcgctg
181 ctgcagggcc agcggcacgg ggtgttcctg gtgcgggact cgagcaccag ccccggggac
241 tatgtgctca gcgtctcaga gaactcgcgc gtctcccact acatcatcaa cagcagcggc
301 ccgcgcccgc cggtgccacc gtcgcccgcc cagcctccgc ccggggtgag cccctccaga
361 ctccgaatag gagatcaaga gtttgattca ttgcctgctt tactggaatt ctacaaaata
421 cactatttgg acactacaac gttgatagaa ccagtttcca gatccaggca gggtagtgga
481 gtgattctca ggcaggagga ggcggagtat gtgcgagccc tctttgactt taatgggaat
541 gatgaggaag atcttccctt taagaaagga gacatcttga gaatccggga caagcctgaa
601 gagcagtggt ggaatgcgga ggacagcgaa ggcaagagag ggatgattcc agtcccttac
661 gtcgagaagt atagacctgc ctccgcctca gtatcggctc tgattggagg taaccaggag
721 ggttcccacc cacagccact gggtgggccg gagcctgggc cctatgccca acccagcgtc
781 aacactccgc tccctaacct ccagaatggg cccatatatg ccagggttat ccagaagcga
841 gtccccaatg cctacgacaa gacagccttg gctttggagg tcggtgagct ggtaaaggtt
901 acgaagatta atgtgagtgg tcagtgggaa ggggagtgta atggcaaacg aggtcacttc
961 ccattcacac atgtccgtct gctggatcaa cagaatcccg atgaggactt cagctgagta
1021 tagttcaaca gttttgctga cagatgggaa caatcttttt tttttttttc caactgccat
1081 ctatacaatt ttcttacaga tgtcaaaagc agtctagttt atataagcat tctgttacct
1141 gtgatatttt ttagactgaa ctgctccatt cctagtctta attaccatat tcagggtacg
1201 aactggaggg cttgtgtgtt agcttctgaa ttggcaattg gaggcggtag tggtcgtgcc
1261 tgtgtgtatc agaagggata ggtatcttgc ctcctttctc tcaggcagtg caaatcaccc
1321 tgtggaaaac cgatggacag gaaggagtgt tacacactgc ttaccctgat ttattcagtg
1381 gttttgtttt cattctggaa ccatactatc aaatggcgac agactgttcc gttccacccc
1441 cgtgaagtaa tcatgcaccg tgtgaatagt atcaagcagg attgctttca ttgtatggag
1501 catgaccagc gtgtgactca ttctgacatt tcagatccta agaattctaa gaacactact
1561 agaagcattt gttccctcct agtcaatgct tcatactttt tcttgggatt cttttagccc
1621 ttgacattct tgtcccccaa acctgtaagt aggtgaattc ctaagataag tgtgtatttt
1681 cattccaggt gaaaagcagg atgtaccgag cactttattc agtgcatagc tttaagccag
1741 tgttggattc actaagtgga cagccagtct cccagctctc tgccttcccc aaaagggtcg
1801 tagtaggtca cccttctaca gcagctaact agagtcctaa ctaatgggat ccagcagggc
1861 catttctcca gagggccagt atcctattag gagactcttg gaattcttag gttctactca
1921 agagtggaag gaccaatcac ctctgatatt ctgtggaagg ttttggggtc aaattctgcc
1981 ctctgcattc tgtgcaactt gtataaaagt caagttagta ttacatgaat ttggggtagg
2041 gttagtgctt tgaaaaaatg ttgaaccggc tgggcgcggt ggctcacgtc tgtaatccca
2101 gcactttggg aggccgaggc gggtggatca tgaggtcagg agttcgagac cagcctggcc
2161 aacatagtga aaccccatct ctgctaaaga tataaaaaat tagcccggcg tggtggtgca
2221 cgcctgtaat cccagctact cgggaggctg aggcaggaga attgcttcaa cctgggaggt
2281 ggaggctgca gtgagccgag atcgcaccac tgcgttccag cctgagcgac agggcaagac
2341 tcagtctcaa aaaaaaaaaa aaggaaaaaa aaaaaaaaaa aa
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