LOCUS BC001525 1187 bp mRNA linear HUM 12-FEB-2004
DEFINITION Homo sapiens TBC1 domain family, member 16, mRNA (cDNA clone
IMAGE:3050107), partial cds.
ACCESSION BC001525
VERSION BC001525.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1187)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1187)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (21-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC001525.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 3 Row: l Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..1187
/db_xref="H-InvDB:HIT000086027"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3050107"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1187
/gene="TBC1D16"
/gene_synonym="FLJ20748"
/gene_synonym="MGC25062"
/db_xref="GeneID:125058"
CDS <1..904
/gene="TBC1D16"
/gene_synonym="FLJ20748"
/gene_synonym="MGC25062"
/codon_start=2
/product="TBC1D16 protein"
/protein_id="AAH01525.2"
/db_xref="GeneID:125058"
/translation="ESGGRRHSGPGRREPQRETDFKMKVAPDKTCMQFSIRRPKLPSS
ETHPEESMYKRLGVSAWLNHLNELGQVEEEYKLRKAIFFGGIDVSIRGEVWPFLLRYY
SHESTSEEREALRLQKRKEYSEIQQKRLSMTPEEHRAFWRNVQFTVDKDVVRTDRNNQ
FFRGEDNPNVESMRRILLNYAVYNPAVGYSQGMSDLVAPILAEVLDESDTFWCFVGLM
QNTIFVSSPRDEDMEKQLLYLRELLRLTHVRFYQHLVSLGEDGLQMLFCHRWLLLCFK
REFPEAEALRIWEACWAHYQGADV"
misc_feature 251..883
/gene="TBC1D16"
/gene_synonym="FLJ20748"
/gene_synonym="MGC25062"
/note="TBC; Region: Domain in Tre-2, BUB2p, and Cdc16p.
Probable Rab-GAPs. Widespread domain present in Gyp6 and
Gyp7, thereby giving rise to the notion that it performs a
GTP-activator activity on Rab-like GTPases"
/db_xref="CDD:smart00164"
BASE COUNT 280 a 324 c 364 g 219 t
ORIGIN
1 agagagtggg gggcggcggc acagtgggcc ggggaggaga gagccgcaga gggaaaccga
61 ttttaagatg aaggtcgccc ccgataagac atgcatgcag ttctccatcc gccgccccaa
121 gctgccgtcc tccgagacgc accccgagga gagcatgtac aagaggctcg gcgtctccgc
181 ctggctcaac cacctgaatg agctgggcca ggtggaggag gagtacaagc tgcggaaggc
241 cattttcttt ggcggtattg atgtgtcaat ccgcggggag gtctggccct tcctgctgcg
301 ctattacagc cacgagtcca cgtcggagga gcgggaggcg ctgcggctgc agaagcgaaa
361 ggagtactct gagatccagc agaaaaggct ctccatgact cccgaggagc acagagcgtt
421 ctggcgtaat gtgcagttca ctgtggacaa agacgtggtc cggacagatc ggaacaacca
481 gttcttccgg ggggaagaca atcccaatgt ggagagcatg aggaggatcc tgctgaacta
541 cgccgtgtac aaccctgccg tcggctattc ccaagggatg tcggacctgg tggcgcccat
601 cttggccgag gtcctggatg agtcagacac cttctggtgc tttgtgggtt tgatgcagaa
661 cacgatcttc gtcagctcac cccgggacga ggacatggag aaacaactgc tgtacctgcg
721 cgagctgctg cggctgacgc acgtgcgctt ctaccagcac ctggtctcgc tgggcgagga
781 cggcctgcag atgctcttct gccaccgctg gctccttctg tgcttcaagc gggagttccc
841 cgaggccgaa gcgctgcgga tctgggaggc ctgctgggcc cactaccagg gggctgatgt
901 ctgatgaaag cgagtctgaa gccaccgagt gccggtacca cacgccacct ttgcatgcgg
961 tcatcggctc gcccctgtcc cgggtctagg tttccctcct ggctcagcct gctggacgtg
1021 gacgtgcagg gtggacgatc tgcattaacg aagggaagca cggcatggac ggtctgagag
1081 gcttcattcc caccactccc gaattaaaaa aaatcgtgcc tcattgcacg ttttcccagt
1141 gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//