LOCUS BC001504 1839 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens pyrroline-5-carboxylate reductase 1, mRNA (cDNA clone
MGC:2273 IMAGE:3505512), complete cds.
ACCESSION BC001504
VERSION BC001504.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1839)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1839)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC001504.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: n Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24797096.
FEATURES Location/Qualifiers
source 1..1839
/db_xref="H-InvDB:HIT000030460"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2273 IMAGE:3505512"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1839
/gene="PYCR1"
/gene_synonym="P5C"
/gene_synonym="P5CR"
/gene_synonym="PIG45"
/gene_synonym="PP222"
/gene_synonym="PYCR"
/db_xref="GeneID:5831"
/db_xref="HGNC:HGNC:9721"
/db_xref="MIM:179035"
CDS 41..1000
/gene="PYCR1"
/gene_synonym="P5C"
/gene_synonym="P5CR"
/gene_synonym="PIG45"
/gene_synonym="PP222"
/gene_synonym="PYCR"
/codon_start=1
/product="pyrroline-5-carboxylate reductase 1"
/protein_id="AAH01504.1"
/db_xref="GeneID:5831"
/db_xref="HGNC:HGNC:9721"
/db_xref="MIM:179035"
/translation="MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSA
LRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTIS
SIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT
EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLL
HSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQ
VSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD"
BASE COUNT 362 a 580 c 536 g 361 t
ORIGIN
1 gccatctgtg ggggctttgg gccaggggtc tccggacagc atgagcgtgg gcttcatcgg
61 cgctggccag ctggcttttg ccctggccaa gggcttcaca gcagcaggcg tcttggctgc
121 ccacaagata atggctagct ccccagacat ggacctggcc acagtttctg ctctcaggaa
181 gatgggggtg aagttgacac cccacaacaa ggagacggtg cagcacagtg atgtgctctt
241 cctggctgtg aagccacaca tcatcccctt catcctggat gaaataggcg ccgacattga
301 ggacagacac attgtggtgt cctgcgcggc cggcgtcacc atcagctcca ttgagaagaa
361 gctgtcagcg tttcggccag cccccagggt catccgctgc atgaccaaca ctccagtcgt
421 ggtgcgggag ggggccaccg tgtatgccac aggcacgcac gcccaggtgg aggacgggag
481 gctcatggag cagctgctga gcagcgtggg cttctgcacg gaggtggaag aggacctgat
541 tgatgccgtc acggggctca gtggcagcgg ccccgcctac gcattcacag ccctggatgc
601 cctggctgat gggggcgtga agatgggact tccaaggcgc ctggcagtcc gcctcggggc
661 ccaggccctc ctgggggctg ccaagatgct gctgcactca gaacagcacc caggccagct
721 caaggacaac gtcagctctc ctggtggggc caccatccat gccttgcatg tgctggagag
781 tgggggcttc cgctccctgc tcatcaacgc tgtggaggcc tcctgcatcc gcacacggga
841 gctgcagtcc atggctgacc aggagcaggt gtcaccagcc gccatcaaga agaccatcct
901 ggacaaggtg aagctggact cccctgcagg gaccgctctg tcgccttctg gccacaccaa
961 gctgctcccc cgcagcctgg ccccagcggg caaggattga cacgtcctgc ctgaccacca
1021 tcctgccacc accttctctt ctcttgtcac tagggggact agggggtccc caaagtggcc
1081 cactttctgt ggctctgatc agcgcagggg ccagccaggg acatagccag ggaggggcca
1141 catcacttcc cactggaaat ctctgtggtc tgcaagtgct tcccagccca gaacaggggt
1201 ggattcccca acctcaacct cctttcttct ctgctcccaa accatgtcag gaccaccttc
1261 ctctagagct cgggagcccg gagggtcttc acccactcct actccagtat cagctggcac
1321 gggctccttc ctgagagcaa aggtcaagga ccccctctgt gaaggctcag cagaggtggg
1381 atcccacgcc ccctcccggc ccctccctgc cctccattca gggagaaacc tctccttccc
1441 gtgtgagaag ggccagaggg tccaggcatc ccaagtccag cgtgaagggc cacagcccct
1501 cttggctgcc aagcacgcag atcccatgga catttgggga aagggctcct tgggctgctg
1561 gtgaacttct gtggccacca cctcctgctc ctgacctccc tgggagggtg ctatcagttc
1621 tgtcctggcc ctttcagttt tataagttgg tttccagccc ccagtgtcct gacttctgtc
1681 tgccacatga ggagggaggc cctgcctgtg tgggagggtg gttactgtgg gtggaatagt
1741 ggaggccttc aactgattag acaaggcccg cccacatctt ggagggcatc tgccttactg
1801 attaaaatgt caatgtaatc taaaaaaaaa aaaaaaaaa
//