LOCUS BC001349 1923 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens phosphoglycerate dehydrogenase, mRNA (cDNA clone
MGC:8621 IMAGE:2961389), complete cds.
ACCESSION BC001349
VERSION BC001349.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1923)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1923)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC001349.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: m Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23308576.
FEATURES Location/Qualifiers
source 1..1923
/db_xref="H-InvDB:HIT000030335"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8621 IMAGE:2961389"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1923
/gene="PHGDH"
/gene_synonym="3-PGDH"
/gene_synonym="3PGDH"
/gene_synonym="MGC3017"
/gene_synonym="PDG"
/gene_synonym="PGAD"
/gene_synonym="PGD"
/gene_synonym="PGDH"
/gene_synonym="SERA"
/db_xref="GeneID:26227"
/db_xref="HGNC:HGNC:8923"
/db_xref="MIM:606879"
CDS 63..1664
/gene="PHGDH"
/gene_synonym="3-PGDH"
/gene_synonym="3PGDH"
/gene_synonym="MGC3017"
/gene_synonym="PDG"
/gene_synonym="PGAD"
/gene_synonym="PGD"
/gene_synonym="PGDH"
/gene_synonym="SERA"
/codon_start=1
/product="phosphoglycerate dehydrogenase"
/protein_id="AAH01349.1"
/db_xref="GeneID:26227"
/db_xref="HGNC:HGNC:8923"
/db_xref="MIM:606879"
/translation="MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAE
LQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGN
SLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREV
ATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLN
DNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHE
NVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIG
LAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVN
AKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNG
AVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHV
MGISSLLPSLEAWKQHVTEAFQFHF"
BASE COUNT 479 a 515 c 551 g 378 t
ORIGIN
1 ccgcagcttc ttggcttagg tacttctact cacagcggcc gattccgagg ccaactccag
61 caatggcttt tgcaaatctg cggaaagtgc tcatcagtga cagcctggac ccttgctgcc
121 ggaagatctt gcaagatgga gggctgcagg tggtggaaaa gcagaacctt agcaaagagg
181 agctgatagc ggagctgcag gactgtgaag gccttattgt tcgctctgcc accaaggtga
241 ccgctgatgt catcaacgca gctgagaaac tccaggtggt gggcagggct ggcacaggtg
301 tggacaatgt ggatctggag gccgcaacaa ggaagggcat cttggttatg aacaccccca
361 atgggaacag cctcagtgcc gcagaactca cttgtggaat gatcatgtgc ctggccaggc
421 agattcccca ggcgacggct tcgatgaagg acggcaaatg ggagcggaag aagttcatgg
481 gaacagagct gaatggaaag accctgggaa ttcttggcct gggcaggatt gggagagagg
541 tagctacccg gatgcagtcc tttgggatga agactatagg gtatgacccc atcatttccc
601 cagaggtctc ggcctccttt ggtgttcagc agctgcccct ggaggagatc tggcctctct
661 gtgatttcat cactgtgcac actcctctcc tgccctccac gacaggcttg ctgaatgaca
721 acacctttgc ccagtgcaag aagggggtgc gtgtggtgaa ctgtgcccgt ggagggatcg
781 tggacgaagg cgccctgctc cgggccctgc agtctggcca gtgtgccggg gctgcactgg
841 acgtgtttac ggaagagccg ccacgggacc gggccttggt ggaccatgag aatgtcatca
901 gctgtcccca cctgggtgcc agcaccaagg aggctcagag ccgctgtggg gaggaaattg
961 ctgttcagtt cgtggacatg gtgaagggga aatctctcac gggggttgtg aatgcccagg
1021 cccttaccag tgccttctct ccacacacca agccttggat tggtctggca gaagctctgg
1081 ggacactgat gcgagcctgg gctgggtccc ccaaagggac catccaggtg ataacacagg
1141 gaacatccct gaagaatgct gggaactgcc taagccccgc agtcattgtc ggcctcctga
1201 aagaggcttc caagcaggcg gatgtgaact tggtgaacgc taagctgctg gtgaaagagg
1261 ctggcctcaa tgtcaccacc tcccacagcc ctgctgcacc aggggagcaa ggcttcgggg
1321 aatgcctcct ggccgtggcc ctggcaggcg ccccttacca ggctgtgggc ttggtccaag
1381 gcactacacc tgtactgcag gggctcaatg gagctgtctt caggccagaa gtgcctctcc
1441 gcagggacct gcccctgctc ctattccgga ctcagacctc tgaccctgca atgctgccta
1501 ccatgattgg cctcctggca gaggcaggcg tgcggctgct gtcctaccag acttcactgg
1561 tgtcagatgg ggagacctgg cacgtcatgg gcatctcctc cttgctgccc agcctggaag
1621 cgtggaagca gcatgtgact gaagccttcc agttccactt ctaaccttgg agctcactgg
1681 tccctgcctc tggggctttt ctgaagaaac ccacccactg tgatcaatag ggagagaaaa
1741 tccacattct tgggctgaac gcgggcctct gacactgctt acactgcact ctgaccctgt
1801 agtacagcaa taaccgtcta ataaagagcc tacccccaaa aaaaaaaaaa aaaaaaaaaa
1861 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1921 aaa
//