LOCUS BC001280 2128 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aurora kinase A, mRNA (cDNA clone MGC:5133
IMAGE:3456017), complete cds.
ACCESSION BC001280
VERSION BC001280.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2128)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2128)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 4 Row: b Column: 17.
FEATURES Location/Qualifiers
source 1..2128
/db_xref="H-InvDB:HIT000030286"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5133 IMAGE:3456017"
/tissue_type="Cervix, carcinoma"
/clone_lib="NIH_MGC_12"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2128
/gene="AURKA"
/gene_synonym="AIK"
/gene_synonym="ARK1"
/gene_synonym="AURA"
/gene_synonym="AURORA2"
/gene_synonym="BTAK"
/gene_synonym="MGC34538"
/gene_synonym="STK7"
/db_xref="GeneID:6790"
/db_xref="HGNC:HGNC:11393"
/db_xref="MIM:603072"
CDS 133..1344
/gene="AURKA"
/gene_synonym="AIK"
/gene_synonym="ARK1"
/gene_synonym="AURA"
/gene_synonym="AURORA2"
/gene_synonym="BTAK"
/gene_synonym="MGC34538"
/gene_synonym="STK7"
/codon_start=1
/product="aurora kinase A"
/protein_id="AAH01280.1"
/db_xref="GeneID:6790"
/db_xref="HGNC:HGNC:11393"
/db_xref="MIM:603072"
/translation="MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQA
QRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPL
PSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILA
LKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTV
YRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFG
WSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY
QETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSN
CQNKESASKQS"
BASE COUNT 620 a 462 c 486 g 560 t
ORIGIN
1 cttggaagac ttgggtcctt gggtcgcagg ctggagtgca atggtgtgat ctcagctcac
61 tgcaacctct gcttcctggg tttaagtgat tctcctgcct cagcctcccg agtagctggg
121 attacaggca tcatggaccg atctaaagaa aactgcattt caggacctgt taaggctaca
181 gctccagttg gaggtccaaa acgtgttctc gtgactcagc aatttccttg tcagaatcca
241 ttacctgtaa atagtggcca ggctcagcgg gtcttgtgtc cttcaaattc ttcccagcgc
301 gttcctttgc aagcacaaaa gcttgtctcc agtcacaagc cggttcagaa tcagaagcag
361 aagcaattgc aggcaaccag tgtacctcat cctgtctcca ggccactgaa taacacccaa
421 aagagcaagc agcccctgcc atcggcacct gaaaataatc ctgaggagga actggcatca
481 aaacagaaaa atgaagaatc aaaaaagagg cagtgggctt tggaagactt tgaaattggt
541 cgccctctgg gtaaaggaaa gtttggtaat gtttatttgg caagagaaaa gcaaagcaag
601 tttattctgg ctcttaaagt gttatttaaa gctcagctgg agaaagccgg agtggagcat
661 cagctcagaa gagaagtaga aatacagtcc caccttcggc atcctaatat tcttagactg
721 tatggttatt tccatgatgc taccagagtc tacctaattc tggaatatgc accacttgga
781 acagtttata gagaacttca gaaactttca aagtttgatg agcagagaac tgctacttat
841 ataacagaat tggcaaatgc cctgtcttac tgtcattcga agagagttat tcatagagac
901 attaagccag agaacttact tcttggatca gctggagagc ttaaaattgc agattttggg
961 tggtcagtac atgctccatc ttccaggagg accactctct gtggcaccct ggactacctg
1021 ccccctgaaa tgattgaagg tcggatgcat gatgagaagg tggatctctg gagccttgga
1081 gttctttgct atgaattttt agttgggaag cctccttttg aggcaaacac ataccaagag
1141 acctacaaaa gaatatcacg ggttgaattc acattccctg actttgtaac agagggagcc
1201 agggacctca tttcaagact gttgaagcat aatcccagcc agaggccaat gctcagagaa
1261 gtacttgaac acccctggat cacagcaaat tcatcaaaac catcaaattg ccaaaacaaa
1321 gaatcagcta gcaaacagtc ttaggaatcg tgcaggggga gaaatccttg agccagggct
1381 gccatataac ctgacaggaa catgctactg aagtttattt taccattgac tgctgccctc
1441 aatctagaac gctacacaag aaatatttgt tttactcagc aggtgtgcct taacctccct
1501 attcagaaag ctccacatca ataaacatga cactctgaag tgaaagtagc cacgagaatt
1561 gtgctactta tactggttca taatctggag gcaaggttcg actgcagccg ccccgtcagc
1621 ctgtgctagg catggtgtct tcacaggagg caaatccaga gcctggctgt ggggaaagtg
1681 accactctgc cctgaccccg atcagttaag gagctgtgca ataaccttcc tagtacctga
1741 gtgagtgtgt aacttattgg gttggcgaag cctggtaaag ctgttggaat gagtatgtga
1801 ttctttttaa gtatgaaaat aaagatatat gtacagactt gtattttttc tctggtggca
1861 ttcctttagg aatgctgtgt gtctgtccgg caccccggta ggcctgattg ggtttctagt
1921 cctccttaac cacttatctc ccatatgaga gtgtgaaaaa taggaacacg tgctctacct
1981 ccatttaggg atttgcttgg gatacagaag aggccatgtg tctcagagct gttaagggct
2041 tattttttta aaacattgga gtcatagcat gtgtgtaaac tttaaatatg caaataaata
2101 agtatctatg tcaaaaaaaa aaaaaaaa
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