LOCUS BC001042 1798 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens sirtuin (silent mating type information regulation 2
homolog) 3 (S. cerevisiae), mRNA (cDNA clone MGC:1104
IMAGE:2823471), complete cds.
ACCESSION BC001042
VERSION BC001042.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1798)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1798)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC001042.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 2 Row: j Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 63054856.
FEATURES Location/Qualifiers
source 1..1798
/db_xref="H-InvDB:HIT000030094"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1104 IMAGE:2823471"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1798
/gene="SIRT3"
/gene_synonym="SIR2L3"
/db_xref="GeneID:23410"
/db_xref="HGNC:HGNC:14931"
/db_xref="MIM:604481"
CDS 18..1217
/gene="SIRT3"
/gene_synonym="SIR2L3"
/codon_start=1
/product="sirtuin (silent mating type information
regulation 2 homolog) 3 (S. cerevisiae)"
/protein_id="AAH01042.1"
/db_xref="GeneID:23410"
/db_xref="HGNC:HGNC:14931"
/db_xref="MIM:604481"
/translation="MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRD
DVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSI
SFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSP
GSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHD
KGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADR
VPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAV
RSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETG
KLDGPDK"
BASE COUNT 371 a 484 c 538 g 405 t
ORIGIN
1 ctcggactgc gcggaacatg gcgttctggg gttggcgcgc cgcggcagcc ctccggctgt
61 ggggccgggt agttgaacgg gtcgaggccg ggggaggcgt ggggccgttt caggcctgcg
121 gctgtcggct ggtgcttggc ggcagggacg atgtgagtgc ggggctgaga ggcagccatg
181 gggcccgcgg tgagcccttg gacccggcgc gccccttgca gaggcctccc agacccgagg
241 tgcccagggc attccggagg cagccgaggg cagcagctcc cagtttcttc ttttcgagta
301 ttaaaggtgg aagaaggtcc atatcttttt ctgtgggtgc ttcaagtgtt gttggaagtg
361 gaggcagcag tgacaagggg aagctttccc tgcaggatgt agctgagctg attcgggcca
421 gagcctgcca gagggtggtg gtcatggtgg gggccggcat cagcacaccc agtggcattc
481 cagacttcag atcgccgggg agtggcctgt acagcaacct ccagcagtac gatctcccgt
541 accccgaggc catttttgaa ctcccattct tctttcacaa ccccaagccc tttttcactt
601 tggccaagga gctgtaccct ggaaactaca agcccaacgt cactcactac tttctccggc
661 tgcttcatga caaggggctg cttctgcggc tctacacgca gaacatcgat gggcttgaga
721 gagtgtcggg catccctgcc tcaaagctgg ttgaagctca tggaaccttt gcctctgcca
781 cctgcacagt ctgccaaaga cccttcccag gggaggacat tcgggctgac gtgatggcag
841 acagggttcc ccgctgcccg gtctgcaccg gcgttgtgaa gcccgacatt gtgttctttg
901 gggagccgct gccccagagg ttcttgctgc atgtggttga tttccccatg gcagatctgc
961 tgctcatcct tgggacctcc ctggaggtgg agccttttgc cagcttgacc gaggccgtgc
1021 ggagctcagt tccccgactg ctcatcaacc gggacttggt ggggcccttg gcttggcatc
1081 ctcgcagcag ggacgtggcc cagctggggg acgtggttca cggcgtggaa agcctagtgg
1141 agcttctggg ctggacagaa gagatgcggg accttgtgca gcgggaaact gggaagcttg
1201 atggaccaga caaataggat gatggctgcc cccacacaat aaatggtaac ataggagaca
1261 tccacatccc aattctgaca agacctcatg cctgaagaca gcttgggcag gtgaaaccag
1321 aatatgtgaa ctgagtggac acccgaggct gccactggaa tgtcttctca ggccatgagc
1381 tgcagtgact ggtagggctg tgtttacagt cagggccacc ccgtcacata tacaaaggag
1441 ctgcctgcct gtttgctgtg ttgaactctt cactctgctg aagctcctaa tggaaaaagc
1501 tttcttctga ctgtgaccct cttgaactga atcagaccaa ctggaatccc agaccgagtc
1561 tgctttctgt gcctagttga acggcaagct cggcatctgt tggttacaag atccagactt
1621 gggccgagcg gtccccagcc ctcttcatgt tccgaagtgt agtcttgagg ccctggtgcc
1681 gcacttctag catgttggtc tcctttagtg gggctatttt taatgagaga aaatctgttc
1741 tttccagcat gaaatacatt tagtctcctc aaaaaaaaaa aaaaaaaaaa aaaaaaaa
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