LOCUS BC000977 3117 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aminolevulinate, delta-, dehydratase, mRNA (cDNA clone
MGC:5057 IMAGE:2900963), complete cds.
ACCESSION BC000977
VERSION BC000977.3
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3117)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3117)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC000977.2.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 3 Row: k Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51558761.
FEATURES Location/Qualifiers
source 1..3117
/db_xref="H-InvDB:HIT000030039"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5057 IMAGE:2900963"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3117
/gene="ALAD"
/gene_synonym="ALADH"
/gene_synonym="MGC5057"
/gene_synonym="PBGS"
/db_xref="GeneID:210"
/db_xref="HGNC:HGNC:395"
/db_xref="MIM:125270"
CDS 100..1119
/gene="ALAD"
/gene_synonym="ALADH"
/gene_synonym="MGC5057"
/gene_synonym="PBGS"
/codon_start=1
/product="aminolevulinate, delta-, dehydratase"
/protein_id="AAH00977.3"
/db_xref="GeneID:210"
/db_xref="HGNC:HGNC:395"
/db_xref="MIM:125270"
/translation="MPLCPLAHAMQPQSVLHSGYFHPLLRAWQTATTTLNASNLIYPI
FVTDVPDDIQPITSLPGVARYGVKRLEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSA
ADSEESPAIEAIHLLRKTFPNLLVACDVCLCPYTSHGHCGLLSENGAFRAEESRQRLA
EVALAYAKAGCQVVAPSDMMDGRVEAIKEALMAHGLGNRVSVMSYSAKFASCFYGPFR
DAAKSSPAFGDRRCYQLPPGARGLALRAVDRDVREGADMLMVKPGMPYLDIVREVKDK
HPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEAMTAFRRAGADIIITYYTPQLLQ
WLKEE"
BASE COUNT 823 a 764 c 852 g 678 t
ORIGIN
1 gcgggagaca gcggtgacag gagcagcggc cgggagccct tagggaggca gacagagcct
61 gcagccaatg ccccaggagc cctcggttcc aaccaactga tgcccctgtg cccactggcc
121 cacgccatgc agccccagtc cgttctgcac agcggctact tccacccact acttcgggcc
181 tggcagacag ccaccaccac cctcaatgcc tccaacctca tctaccccat ctttgtcacg
241 gatgttcctg atgacataca gcctatcacc agcctcccag gagtggccag gtacggtgtg
301 aagcggctgg aagagatgct gaggcccttg gtggaagagg gcctacgctg tgtcttgatc
361 tttggcgtcc ccagcagagt tcccaaggac gagcggggtt ccgcagctga ctccgaggag
421 tccccagcta ttgaggcaat ccatctgttg aggaagacct tccccaacct cctggtggcc
481 tgtgatgtct gcctgtgtcc ctacacctcc catggtcact gcgggctcct gagtgaaaac
541 ggagcattcc gggctgagga gagccgccag cggctggctg aggtggcatt ggcgtatgcc
601 aaggcaggat gtcaggtggt agccccgtcg gacatgatgg atggacgcgt ggaagccatc
661 aaagaggccc tgatggcaca tggacttggc aacagggtat cggtgatgag ctacagtgcc
721 aaatttgctt cctgtttcta tggccctttc cgggatgcag ctaagtcaag cccagctttt
781 ggggaccgcc gctgctacca gctgccccct ggagcacgag gcctggctct ccgagctgtg
841 gaccgggatg tacgggaagg agctgacatg ctcatggtga agccgggaat gccctacctg
901 gacatcgtgc gggaggtaaa ggacaagcac cctgacctcc ctctcgccgt gtaccacgtc
961 tctggagagt ttgccatgct gtggcatgga gcccaggccg gggcatttga tctcaaggct
1021 gccgtactgg aggccatgac tgccttccgc agagcaggtg ctgacatcat catcacctac
1081 tacacaccgc agctgctgca gtggctgaag gaggaatgat ggagacagtg ccaggcccaa
1141 gaactagaac tttaaaacgt tcccggggcc tcagacaagt gaaaaccaaa gtaaatgctg
1201 cttttagaac tgtgtcctca tgccctcttc ctgctcacat gctagcgggg cccagcagcc
1261 ctgggtggtt ttgccagcat gctaactctt gtaactcgca gctgcatcct atgagctctc
1321 ccaagcttcc ccgcccctcc cctgggtcag ccgtgaggcc cacctttgcc accctcagct
1381 ctttcctctg gtgtggcttc agcttgaaag caacctggag tcgggggcac agcctttggg
1441 gcctggctgg gagagggtct tggagcatta ggggaagaag agagcagtgg gatcttgggg
1501 cctgagaagc cttggaacgc ttctggcagc agagctgggt gtgggaatga ggcctagatc
1561 gatatccctg ggttagagtt gaaatttgcc gcaattccac tggaaggcat ttcccacgag
1621 gccagaggtt gccaggctgc ctgaggtctc ctattctact ctgaaccata aacccagaga
1681 agaattactc attaaccagc ataaatactg cctgaggatc aaaactcaga ggcaaagagg
1741 gagttcctga ctgctagagg tgccaccacc acaaacactt tttattcagg agatactttt
1801 tgagaatctc tgctctgttc ctaggttcag tgctgggtcc tgggaataca gcaggacaga
1861 cctcagctta tctcttcata gaaattatac aaagagaatt ggggagacag ctaagaagaa
1921 aacaaagaaa taaagcagtt acaaattgtg ataagtgctt tgaaggaaag aaggggtctg
1981 agacaacaac agggaagggg cctctcttga aacagtagtt gggaaggagg cagacatgca
2041 ccagtgatgt ggtgacaggt gctctgaagg aggtcaccag gacctgacct ctttgaagga
2101 tcagaaaata cttccctgaa ggactgacat ttgagcctag acctgaaggg tgagccatca
2161 agctaagaca attggggaag agcattccag ggagagggag gagttgtgca aaggccctgg
2221 ggctccttct agctggagga atgcaaggct agcttgtctg gagcactgag aggatggcct
2281 gaactgagtg gagagagaca gaccaggacc aaaccatgca gaggtcaagg gccacattca
2341 ccttttcaga gtgactcaat caaatttgta gtttgtaaaa gtattttaac agctctgcgg
2401 caaagtgcaa atgaaaagtc ttgatggcat ggactggagc ggggacagtg gggatggaga
2461 aaggggaatg gattgtggat gtgtttagaa ggtagattcg atgtgaagga tgaatctggc
2521 ttgaccttct gggtggctga tgggccattt actgagatgg ggcagcctgg aagaggaaca
2581 gaagcagggt cggggtggag ggagaatact aaacttagct tgagacattt tgcaataagg
2641 aagctatatc tagagtgctt atgtgactca cctaaggcca ctcaacaagt ttgtggcaga
2701 actggattag aactgcacag aaaacagcca agctgggatt tgaacccatg tagtccaact
2761 ccaaggcctc tgcccctaac cactgtgcca taccacctcc caataatcaa cagcaaaatt
2821 ataggtctaa caatgtttta tagacacccc tccatttatg tgatgggttt gcatcctgat
2881 aaacccatca taagttgaaa atatgatcat aagttgaaaa tatgatcata agtcaaaaat
2941 gtatttaata tacctaacct accaaacatc atagcttagc ctagcctgcc ttaaacatgc
3001 tcagaacact tacattagcc tacagtgggc aaaactatcc aacacaaaat ctatattgta
3061 ataaagttgt aaagaatttt gaataaaaat tcaatatttg aaaaaaaaaa aaaaaaa
//