LOCUS BC000934 1417 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2, subunit 2
beta, 38kDa, mRNA (cDNA clone MGC:5085 IMAGE:3447202), complete
cds.
ACCESSION BC000934
VERSION BC000934.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1417)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1417)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Feb 23, 2001 this sequence version replaced BC000934.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 3 Row: g Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29826334.
FEATURES Location/Qualifiers
source 1..1417
/db_xref="H-InvDB:HIT000030014"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5085 IMAGE:3447202"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1417
/gene="EIF2S2"
/gene_synonym="EIF2B"
/gene_synonym="EIF2beta"
/gene_synonym="MGC8508"
/db_xref="GeneID:8894"
/db_xref="HGNC:HGNC:3266"
/db_xref="MIM:603908"
CDS 112..1113
/gene="EIF2S2"
/gene_synonym="EIF2B"
/gene_synonym="EIF2beta"
/gene_synonym="MGC8508"
/codon_start=1
/product="eukaryotic translation initiation factor 2,
subunit 2 beta, 38kDa"
/protein_id="AAH00934.1"
/db_xref="GeneID:8894"
/db_xref="HGNC:HGNC:3266"
/db_xref="MIM:603908"
/translation="MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEV
EPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLK
IESDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEALEDEDNKKDDGISFS
NQTGPAWAGSERDYTYDELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTS
FVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIK
EYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN"
BASE COUNT 491 a 255 c 339 g 332 t
ORIGIN
1 agagcctagt gcggtggtgg gagaggtatc ggcaggggca gcgctgccgc cggggcctgg
61 ggctgacccg tctgacttcc cgtccgtgcc gagcccactc gagccgcagc catgtctggg
121 gacgagatga tttttgatcc tactatgagc aagaagaaaa agaagaagaa gaagcctttt
181 atgttagatg aggaagggga tacccaaaca gaggaaaccc agccttcaga aacaaaagaa
241 gtggagccag agccaactga ggacaaggat ttggaagctg atgaagagga cactaggaaa
301 aaagatgctt ctgatgatct agatgacttg aacttcttta atcaaaagaa aaagaagaaa
361 aaaactaaaa agatatttga tattgatgaa gctgaagaag gtgtaaagga tcttaagatt
421 gaaagtgatg ttcaagaacc aactgaacca gaggatgacc ttgacattat gcttggcaat
481 aaaaagaaga aaaagaagaa tgttaagttc ccagatgagg atgaaatact agagaaagat
541 gaagctctag aagatgaaga caacaaaaaa gatgatggta tctcattcag taatcagaca
601 ggccctgctt gggcaggctc agaaagagac tacacatacg atgagctgct gaatcgagtg
661 ttcaacatca tgagggaaaa gaatccagat atggttgctg gggagaaaag gaaatttgtc
721 atgaaacctc cacaagtcgt ccgagtagga accaagaaaa cttcttttgt caactttaca
781 gatatctgta aactattaca tcgtcagccc aaacatctcc ttgcattttt gttggctgaa
841 ttgggtacaa gtggttctat agatggtaat aaccaacttg taatcaaagg aagattccaa
901 cagaaacaga tagaaaatgt cttgagaaga tatatcaagg aatatgtcac ttgtcacaca
961 tgccgatcac cggacacaat cctgcagaag gacacacgac tctatttcct acagtgcgaa
1021 acttgtcatt ctagatgttc tgttgccagt atcaaaaccg gcttccaggc tgtcacgggc
1081 aagcgagcac agctccgtgc caaagctaac taatttgcta atcactgatt ttgcaaagct
1141 tgttgtggag atgtggctgg acaggtttgc catcagagtg gatataccgt tgtattaaaa
1201 acaagataaa aaagctgcca agatttttgg caagtggttg gtctgaagtc cttgcaagac
1261 gctgatgctc aagctgttga catactcatt gcctacttta acacctgtca gagaaacgtg
1321 atatggggta aggaggtgct tttttaaaat cgttcataga cttctgtaaa atgcaagata
1381 aattaaagtt attataacag tgaaaaaaaa aaaaaaa
//