LOCUS BC000879 1284 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens kynureninase (L-kynurenine hydrolase), mRNA (cDNA
clone MGC:5080 IMAGE:3461828), complete cds.
ACCESSION BC000879
VERSION BC000879.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1284)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1284)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 4 Row: d Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504936.
FEATURES Location/Qualifiers
source 1..1284
/db_xref="H-InvDB:HIT000029972"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5080 IMAGE:3461828"
/tissue_type="Cervix, carcinoma"
/clone_lib="NIH_MGC_12"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1284
/gene="KYNU"
/db_xref="GeneID:8942"
/db_xref="HGNC:HGNC:6469"
/db_xref="MIM:236800"
CDS 100..1023
/gene="KYNU"
/codon_start=1
/product="kynureninase (L-kynurenine hydrolase)"
/protein_id="AAH00879.1"
/db_xref="GeneID:8942"
/db_xref="HGNC:HGNC:6469"
/db_xref="MIM:236800"
/translation="MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRE
CFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGH
EVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILL
EAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVI
LFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYK
YLNAGAGGIAGAFIHEKHAHTIKPARSEFFN"
BASE COUNT 425 a 222 c 291 g 346 t
ORIGIN
1 ggcctgtaca ttttcaagga attcttgaga ggttcttgga gagattctgg gagccaaaca
61 ctccattggg atcctagctg ttttagagaa caacttgtaa tggagccttc atctcttgag
121 ctgccggctg acacagtgca gcgcattgcg gctgaactca aatgccaccc aacggatgag
181 agggtggctc tccacctaga tgaggaagat aagctgaggc acttcaggga gtgcttttat
241 attcccaaaa tacaggatct gcctccagtt gatttatcat tagtgaataa agatgaaaat
301 gccatctatt tcttgggaaa ttctcttggc cttcaaccaa aaatggttaa aacatatctt
361 gaagaagaac tagataagtg ggccaaaata gcagcctatg gtcatgaagt ggggaagcgt
421 ccttggatta caggagatga gagtattgta ggccttatga aggacattgt aggagccaat
481 gagaaagaaa tagccctaat gaatgctttg actgtaaatt tacatcttct aatgttatca
541 ttttttaagc ctacgccaaa acgatataaa attcttctag aagccaaagc cttcccttct
601 gatcattatg ctattgagtc acaactacaa cttcacggac ttaacattga agaaagtatg
661 cggatgataa agccaagaga gggggaagaa accttaagaa tagaggatat ccttgaagta
721 attgagaagg aaggagactc aattgcagtg atcctgttca gtggggtgca tttttacact
781 ggacagcact ttaatattcc tgccatcaca aaagctggac aagcgaaggg ttgttatgtt
841 ggctttgatc tagcacatgc agttggaaat gttgaactct acttacatga ctggggagtt
901 gattttgcct gctggtgttc ctacaagtat ttaaatgcag gagcaggagg aattgctggt
961 gccttcattc atgaaaagca tgcccatacg attaaacctg cgagatcgga gttctttaat
1021 taggaatgga atgcaacaga tttggacaag tcaaggacaa gagctttaga gagaccaaag
1081 agtttttcac tgttaaagtg tccagtatgt agccgagaac catatggaga acatcaaata
1141 cagtggaaca aatgtaactg ctattgatgt cacactttgt gaagtagtct ttgttgctta
1201 aaaagggtga catctagtgg ctaaacatgt tatttcaaat aaataatatc gaaataaaaa
1261 aaaaaaaaaa aaaaaaaaaa aaaa
//