LOCUS BC000781 1452 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens HemK methyltransferase family member 1, mRNA (cDNA
clone MGC:740 IMAGE:3505225), complete cds.
ACCESSION BC000781
VERSION BC000781.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1452)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1452)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000781.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: d Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 54792139.
FEATURES Location/Qualifiers
source 1..1452
/db_xref="H-InvDB:HIT000029915"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:740 IMAGE:3505225"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1452
/gene="HEMK1"
/gene_synonym="HEMK"
/gene_synonym="MTQ1"
/db_xref="GeneID:51409"
/db_xref="HGNC:HGNC:24923"
CDS 166..1182
/gene="HEMK1"
/gene_synonym="HEMK"
/gene_synonym="MTQ1"
/codon_start=1
/product="HemK methyltransferase family member 1"
/protein_id="AAH00781.1"
/db_xref="GeneID:51409"
/db_xref="HGNC:HGNC:24923"
/translation="MELWGRMLWALLSGPGRRGSTRGWAFSSWQPQPPLAGLSSAIEL
VSHWTGVFEKRGIPEARESSEYIVAHVLGAKTFQSLRPALWTQPLTSQQLQCIRELSS
RRLQRMPVQYILGEWDFQGLSLRMVPPVFIPRPETEELVEWVLEEVAQRSHAVGSPGS
PLILEVGCGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQRLRLQDRIWIIHLD
MTSERSWTHLPWGPMDLIVSNPPYVFHQDMEQLAPEIRSYEDPAALDGGEEGMDIITH
ILALAPRLLKDSGSIFLEVDPRHPELVSSWLQSRPDLYLNLVAVRRDFCGRPRFLHIR
RSGP"
BASE COUNT 306 a 400 c 433 g 313 t
ORIGIN
1 caactatatc tgaggaccag agccattttg gggcaccaga gcttgtgacc tctccatctc
61 cacccagctg ggtccagggg ccactctcag cactcacctc agcagctgac atcataaagc
121 agacttggga acctggaagc actctggaga acctttccct gagacatgga gctttggggc
181 cgaatgctgt gggccctcct gtctggccca gggaggaggg gaagtacccg gggctgggcc
241 ttcagctcat ggcaacccca accacctctg gctgggttat ccagtgccat agaactggtc
301 agccactgga ctggggtctt tgagaagagg ggtatccctg aggcccggga atccagtgag
361 tacatcgtgg ctcatgtcct tggagccaaa acatttcaga gcctgaggcc ggcactttgg
421 acccagccct tgacctctca gcaactacag tgtatccggg agctgagtag ccgtcgattg
481 cagaggatgc cggtgcagta catccttgga gagtgggact tccaggggct cagcctaagg
541 atggtgcccc cagtgtttat tccgcggcca gaaacagagg aactggttga gtgggtgctg
601 gaagaggtgg cccagaggtc ccatgctgtg ggatccccag gcagccccct cattctggag
661 gtgggctgcg gatcaggagc catctccctc agcctgctga gccagctccc ccagagccga
721 gtcattgctg tggataagcg ggaagctgct atctctctga cccatgagaa tgctcagagg
781 cttcggttgc aggacaggat ttggatcatc cacctcgaca tgacctcaga aaggagctgg
841 acacacctgc cctggggccc catggacctg attgtcagca accctcccta cgtcttccac
901 caggacatgg agcagctggc ccctgagatc cgcagctatg aagaccccgc ggccctggat
961 ggtggggagg agggcatgga catcattacc cacattctgg ccttggcacc ccggctcctg
1021 aaagactctg gtagtatctt cttagaagtg gacccaaggc acccggagct tgtcagcagc
1081 tggcttcaga gccggcctga cctgtacctt aatcttgtgg ctgtgcgcag ggacttctgt
1141 gggaggcccc ggttcctgca tatccggagg tctgggccat agcatggctg ccctgtggat
1201 gccttgtcag tgccgccagc ctgaccagag gggaggtgga tggcactttc cagagcccag
1261 gttcttatgg catttcccag ggttctgtga tttccccatg ctctgcattt ctaggatatt
1321 tctaggacac ctggattggc tccatcacat cagagtggct gagggcagtt gctctgtgtt
1381 ggtgaaattg ctgtgggggt atcgggggat atggccagta aagtattgag agactaaaaa
1441 aaaaaaaaaa aa
//