LOCUS BC000747 2001 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens exosome component 2, mRNA (cDNA clone MGC:2403
IMAGE:2821702), complete cds.
ACCESSION BC000747
VERSION BC000747.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2001)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2001)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC000747.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 2 Row: a Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39725699.
FEATURES Location/Qualifiers
source 1..2001
/db_xref="H-InvDB:HIT000029890"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2403 IMAGE:2821702"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2001
/gene="EXOSC2"
/gene_synonym="hRrp4p"
/gene_synonym="p7"
/gene_synonym="RRP4"
/gene_synonym="Rrp4p"
/db_xref="GeneID:23404"
/db_xref="HGNC:HGNC:17097"
/db_xref="MIM:602238"
CDS 3..884
/gene="EXOSC2"
/gene_synonym="hRrp4p"
/gene_synonym="p7"
/gene_synonym="RRP4"
/gene_synonym="Rrp4p"
/codon_start=1
/product="exosome component 2"
/protein_id="AAH00747.1"
/db_xref="GeneID:23404"
/db_xref="HGNC:HGNC:17097"
/db_xref="MIM:602238"
/translation="MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHG
TYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNS
RLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRS
LKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGG
FIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEI
MEEIVMETRQRLLEQEG"
BASE COUNT 565 a 427 c 539 g 470 t
ORIGIN
1 agatggcgat ggagatgagg cttccagtgg ctcgcaagcc tcttagcgag agactgggcc
61 gcgacactaa gaaacatcta gtggtgccgg gggatacaat cactacggac acaggattca
121 tgcggggcca tggaacgtat atgggagaag agaagctcat tgcatctgtt gctggctctg
181 tggagagagt aaacaagttg atctgtgtga aagctttgaa aaccagatac attggtgaag
241 taggagacat cgtagtggga cgaatcacag aggttcaaca gaagaggtgg aaggtggaga
301 ccaactccag gctggattcg gtcttgctgc tctcgtccat gaaccttcct ggaggagagc
361 tgaggagaag atctgcagaa gatgagcttg caatgagagg tttcttacag gaaggggacc
421 ttatcagtgc tgaggtccag gcagtgttct ctgacggagc tgtctctttg cacacgagga
481 gcctgaaata tggaaaacta ggtcaggggg ttttggtcca ggtttccccc tccctggtga
541 aacggcagaa gacccacttt catgatttgc catgtggtgc ctcagtgatt ctcggtaaca
601 acggcttcat ctggatttac ccaacacctg agcacaaaga agaggaagca gggggcttca
661 ttgcaaacct ggagcctgtc tctcttgctg atcgagaggt gatatcccgg cttcggaact
721 gcatcatctc gctggtaact cagaggatga tgctgtatga taccagcatc ctgtactgct
781 atgaagcatc ccttccacat cagatcaaag acatcttaaa gccagaaata atggaggaga
841 ttgtgatgga aacacgccag aggcttttgg aacaggaggg ataaggaggt gctccagaag
901 cacgggactg tggaccttgc aggagtgaag actgtgatgt gtggtcccca tatgtggctc
961 agcaaagact cgagagatca tccctttgtc tgcattgacg gccctgtgac ggcctccagc
1021 ccacaggcct gctttctcct gtcctaacac caagcctggg tggcagatga acagtgcttc
1081 cttgggttgc cagctgagtc ccggtattag ggaatagttt cagctctttc aaagtgcaca
1141 gtgttacagt cgaatgggct cccatcctgg aataatatgg agaatccttt gtcttccact
1201 cactgtcatt cacaaggcac agtgccccat gaaattgccc caatagaaaa catggcatcc
1261 ctgacctcca aatggtctgt tttggcctcc attcctatat cctttaaatg actgagaatg
1321 cagctggtaa agttggaaga ataaagttaa ccaagcaggc caggcacggt ggctcacgcc
1381 tataatccca gcacttaggg aggccaaggc gggcagatca cctgaggtca atagttcgag
1441 accagcctgg ccaacaaggt gaaaccccat ctctactaaa aatacaaaaa attagccagg
1501 tgtggtggtg tgcacctgta gtcccagcta tttgggaggc tgaggtggga gaatcacttg
1561 aacctgggag gcggaggttg cagtgagctg aaatcgcgta ccacactcca gcctgggtga
1621 cagagcgaga ctgtgtttca aagaaaaaaa aaaacaagca gccttttgct tggttggaat
1681 ctgattttct gttgcgtgtt ccttgtagcc atagatgtga ttatgtccac accgggctgc
1741 cttaatctgt cctgcttgga gagtgacttg taagatgctg aattattcat gataatacag
1801 tgaatgttct gggtccatgt actcagataa acatgaagaa aataagcaaa gaaaaatgga
1861 gactgggaaa gcaaagctgt tttcatccta taattgaagt agtgtggagc attaacttgt
1921 ggatgattca gagttaaaag ataaaaagac gccagagttc tcgctgaaga atgtgagaaa
1981 aaaaaaaaaa aaaaaaaaaa a
//