LOCUS BC000722 1910 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens sialidase 1 (lysosomal sialidase), mRNA (cDNA clone
MGC:1553 IMAGE:3506824), complete cds.
ACCESSION BC000722
VERSION BC000722.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1910)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1910)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000722.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: o Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40806202.
FEATURES Location/Qualifiers
source 1..1910
/db_xref="H-InvDB:HIT000029867_09"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1553 IMAGE:3506824"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1910
/gene="NEU1"
/gene_synonym="SIAL1"
/db_xref="GeneID:4758"
/db_xref="HGNC:HGNC:7758"
/db_xref="MIM:608272"
CDS 98..1345
/gene="NEU1"
/gene_synonym="SIAL1"
/codon_start=1
/product="sialidase 1 (lysosomal sialidase)"
/protein_id="AAH00722.1"
/db_xref="GeneID:4758"
/db_xref="HGNC:HGNC:7758"
/db_xref="MIM:608272"
/translation="MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASW
SKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSS
DEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAH
KAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVC
GHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVV
INARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSN
PAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVL
YEKGRNHYTESISVAKISVYGTL"
BASE COUNT 421 a 512 c 542 g 435 t
ORIGIN
1 ggcttaaggg tgacatctgc gctttaaagg gtccgggtca gctgactccc gactctgtgg
61 agtctagctg ccagggtcgc ggcagctgcg gggagagatg actggggagc gacccagcac
121 ggcgctcccg gacagacgct gggggccgcg gattctgggc ttctggggag gctgtagggt
181 ttgggtgttt gccgcgatct tcctgctgct gtctctggca gcctcctggt ccaaggctga
241 gaacgacttc ggtctggtgc agccgctggt gaccatggag caactgctgt gggtgagcgg
301 gagacagatc ggctcagtgg acaccttccg catcccgctc atcacagcca ctccgcgggg
361 cactcttctc gcctttgctg aggcgaggaa aatgtcctca tccgatgagg gggccaagtt
421 catcgccctg cggaggtcca tggaccaggg cagcacatgg tctcctacag cgttcattgt
481 caatgatggg gatgtccccg atgggctgaa ccttggggca gtagtgagcg atgttgagac
541 aggagtagta tttcttttct actccctttg tgctcacaag gccggctgcc aggtggcctc
601 taccatgttg gtatggagca aggatgatgg tgtttcctgg agcacacccc ggaatctctc
661 cctggatatt ggcactgaag tgtttgcccc tggaccgggc tctggtattc agaaacagcg
721 ggagccacgg aagggccgcc tcatcgtgtg tggccatggg acgctggagc gggacggagt
781 cttctgtctc ctcagcgatg atcatggtgc ctcctggcgc tacggaagtg gggtcagcgg
841 catcccctac ggtcagccca agcaggaaaa tgatttcaat cctgatgaat gccagcccta
901 tgagctccca gatggctcag tcgtcatcaa tgcccgaaac cagaacaact accactgcca
961 ctgccgaatt gtcctccgca gctatgatgc ctgtgataca ctaaggcccc gtgatgtgac
1021 cttcgaccct gagctcgtgg accctgtggt agctgcagga gctgtagtca ccagctccgg
1081 cattgtcttc ttctccaacc cagcacatcc agagttccga gtgaacctga ccctgcgatg
1141 gagcttcagc aatggtacct catggcggaa agagacagtc cagctatggc caggccccag
1201 tggctattca tccctggcaa ccctggaggg cagcatggat ggagaggagc aggcccccca
1261 gctctacgtc ctgtatgaga aaggccggaa ccactacaca gagagcatct ccgtggccaa
1321 aatcagtgtc tatgggacac tctgagctgt gccactgcca caggggtatt ctgccttcag
1381 gactctgcct tcaggaacac gggtctgtag agggtctgct ggagacgcct gaaagacagt
1441 tccatcttcc tttagactcc agccttggca aaatcacctt ccctttacca gggaaatcac
1501 ttcctttagg actgaaagct aggcgtcctc tcccacaaaa aagtcctgcc ctcatctgag
1561 aatactgtct ttccatatgg ctaagtgtgg ccccaccacc ctctctgccc tcccgggaca
1621 ttgattggtc ctgtcttggg caggtctagt gagctgtaga attgaatcaa tgtgaactca
1681 gggaactggg gaaggctgag cctcctcttt ggtgttgcgg taagataacc gacagggctg
1741 gtgaaagtcc ccagatggca ggatatttgg tttcagagta aggactaggt gcaccaccat
1801 gactgactat caatcaaaat gtttgtaact taaaattttt aatgaaggat aatgaatatt
1861 tgtagagtct ctatggttct gtcaatgcaa aaaaaaaaaa aaaaaaaaaa
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