LOCUS BC000511 2018 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens lamin A/C, mRNA (cDNA clone MGC:8539 IMAGE:2822703),
complete cds.
ACCESSION BC000511
VERSION BC000511.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2018)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2018)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC000511.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: j Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27436944.
FEATURES Location/Qualifiers
source 1..2018
/db_xref="H-InvDB:HIT000029693"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8539 IMAGE:2822703"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2018
/gene="LMNA"
/gene_synonym="CDCD1"
/gene_synonym="CDDC"
/gene_synonym="CMT2B1"
/gene_synonym="EMD2"
/gene_synonym="FPL"
/gene_synonym="FPLD"
/gene_synonym="HGPS"
/gene_synonym="IDC"
/gene_synonym="LDP1"
/gene_synonym="LFP"
/gene_synonym="LGMD1B"
/gene_synonym="LMNC"
/gene_synonym="PRO1"
/db_xref="GeneID:4000"
/db_xref="HGNC:HGNC:6636"
/db_xref="MIM:150330"
CDS 181..1899
/gene="LMNA"
/gene_synonym="CDCD1"
/gene_synonym="CDDC"
/gene_synonym="CMT2B1"
/gene_synonym="EMD2"
/gene_synonym="FPL"
/gene_synonym="FPLD"
/gene_synonym="HGPS"
/gene_synonym="IDC"
/gene_synonym="LDP1"
/gene_synonym="LFP"
/gene_synonym="LGMD1B"
/gene_synonym="LMNC"
/gene_synonym="PRO1"
/codon_start=1
/product="lamin A/C"
/protein_id="AAH00511.1"
/db_xref="GeneID:4000"
/db_xref="HGNC:HGNC:6636"
/db_xref="MIM:150330"
/translation="METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAV
YIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARL
QLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEG
ELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRET
KRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQ
SAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTS
RRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPS
PTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGK
FVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSP
PTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHH
VSGSRR"
BASE COUNT 456 a 604 c 665 g 293 t
ORIGIN
1 cagccaaccc agatcccgag gtccgacagc gcccggccca gatccccacg cctgccagga
61 gcaagccgag agccagccgg ccggcgcact ccgactccga gcagtctctg tccttcgacc
121 cgagccccgc gccctttccg ggacccctgc cccgcgggca gcgctgccaa cctgccggcc
181 atggagaccc cgtcccagcg gcgcgccacc cgcagcgggg cgcaggccag ctccactccg
241 ctgtcgccca cccgcatcac ccggctgcag gagaaggagg acctgcagga gctcaatgat
301 cgcttggcgg tctacatcga ccgtgtgcgc tcgctggaaa cggagaacgc agggctgcgc
361 cttcgcatca ccgagtctga agaggtggtc agccgcgagg tgtccggcat caaggccgcc
421 tacgaggccg agctcgggga tgcccgcaag acccttgact cagtagccaa ggagcgcgcc
481 cgcctgcagc tggagctgag caaagtgcgt gaggagttta aggagctgaa agcgcgcaat
541 accaagaagg agggtgacct gatagctgct caggctcggc tgaaggacct ggaggctctg
601 ctgaactcca aggaggccgc actgagcact gctctcagtg agaagcgcac gctggagggc
661 gagctgcatg atctgcgggg ccaggtggcc aagcttgagg cagccctagg tgaggccaag
721 aagcaacttc aggatgagat gctgcggcgg gtggatgctg agaacaggct gcagaccatg
781 aaggaggaac tggacttcca gaagaacatc tacagtgagg agctgcgtga gaccaagcgc
841 cgtcatgaga cccgactggt ggagattgac aatgggaagc agcgtgagtt tgagagccgg
901 ctggcggatg cgctgcagga actgcgggcc cagcatgagg accaggtgga gcagtataag
961 aaggagctgg agaagactta ttctgccaag ctggacaatg ccaggcagtc tgctgagagg
1021 aacagcaacc tggtgggggc tgcccacgag gagctgcagc agtcgcgcat ccgcatcgac
1081 agcctctctg cccagctcag ccagctccag aagcagctgg cagccaagga ggcgaagctt
1141 cgagacctgg aggactcact ggcccgtgag cgggacacca gccggcggct gctggcggaa
1201 aaggagcggg agatggccga gatgcgggca aggatgcagc agcagctgga cgagtaccag
1261 gagcttctgg acatcaagct ggccctggac atggagatcc acgcctaccg caagctcttg
1321 gagggcgagg aggagaggct acgcctgtcc cccagcccta cctcgcagcg cagccgtggc
1381 cgtgcttcct ctcactcatc ccagacacag ggtgggggca gcgtcaccaa aaagcgcaaa
1441 ctggagtcca ctgagagccg cagcagcttc tcacagcacg cacgcactag cgggcgcgtg
1501 gccgtggagg aggtggatga ggagggcaag tttgtccggc tgcgcaacaa gtccaatgag
1561 gaccagtcca tgggcaattg gcagatcaag cgccagaatg gagatgatcc cttgctgact
1621 taccggttcc caccaaagtt caccctgaag gctgggcagg tggtgacgat ctgggctgca
1681 ggagctgggg ccacccacag cccccctacc gacctggtgt ggaaggcaca gaacacctgg
1741 ggctgcggga acagcctgcg tacggctctc atcaactcca ctggggaaga agtggccatg
1801 cgcaagctgg tgcgctcagt gactgtggtt gaggacgacg aggatgagga tggagatgac
1861 ctgctccatc accaccacgt gagtggtagc cgccgctgag gccgagcctg cactggggcc
1921 acccagccag gcctgggggc agcctctccc cagcctcccc gtgccaaaaa tcttttcatt
1981 aaagaatgtt ttggaacttt aaaaaaaaaa aaaaaaaa
//