LOCUS BC000494 1535 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2B, subunit 2
beta, 39kDa, mRNA (cDNA clone MGC:8399 IMAGE:2820668), complete
cds.
ACCESSION BC000494
VERSION BC000494.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1535)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1535)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Nov 6, 2003 this sequence version replaced BC000494.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: d Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7657057.
FEATURES Location/Qualifiers
source 1..1535
/db_xref="H-InvDB:HIT000029676"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8399 IMAGE:2820668"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1535
/gene="EIF2B2"
/gene_synonym="EIF-2Bbeta"
/gene_synonym="EIF2B"
/db_xref="GeneID:8892"
/db_xref="HGNC:HGNC:3258"
/db_xref="MIM:606454"
CDS 49..1104
/gene="EIF2B2"
/gene_synonym="EIF-2Bbeta"
/gene_synonym="EIF2B"
/codon_start=1
/product="eukaryotic translation initiation factor 2B,
subunit 2 beta, 39kDa"
/protein_id="AAH00494.1"
/db_xref="GeneID:8892"
/db_xref="HGNC:HGNC:3258"
/db_xref="MIM:606454"
/translation="MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQ
IITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRTDE
SDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIH
SNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMT
DAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSP
QFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPS
YIYRLMSELYHPDDHVL"
BASE COUNT 411 a 372 c 399 g 353 t
ORIGIN
1 ggcaggtgtg gattccgccg gtgaaggctg aaggcagcta ccttaaagat gccgggatcc
61 gcagcgaagg gctcggagtt gtcagagagg atcgagagct tcgtggagac cctgaagcgg
121 ggtggtgggc cgcgcagctc cgaggaaatg gctcgggaga ccctagggtt gctgcgccag
181 atcatcacgg accaccgctg gagcaacgcg ggggagctga tggagctgat ccgcagagag
241 ggcaggagga tgacggccgc tcagccctcc gagaccaccg tgggcaacat ggtgcggaga
301 gtgctcaaga ttatccggga ggagtatggc agactccatg gacgcaccga cgagagtgat
361 cagcaggagt ccctgcacaa actgttgaca tccggaggcc taaacgagga tttcagcttc
421 cattatgccc aactccagtc caacatcatt gaggcgatta atgagctgct agtggagctg
481 gaagggacaa tggagaacat tgcagcccag gctctggagc acattcactc caatgaggtg
541 atcatgacca ttggcttctc ccgaacagta gaggccttcc tcaaagaggc tgcccgaaag
601 aggaaattcc atgtcattgt agcagagtgt gctcctttct gccagggtca tgaaatggct
661 gtgaatttgt ccaaagcagg tattgagaca actgtcatga ctgatgctgc catttttgcc
721 gttatgtcaa gagtcaacaa ggtgatcatt ggcacgaaga ccatcctggc caatggggcc
781 ctgagagctg tgacaggaac tcacactctg gcactggcag caaaacacca ttccacccca
841 ctcatcgtct gtgcacctat gttcaaactt tctccacagt tccccaatga agaagactca
901 tttcataagt ttgtggctcc tgaagaagtc ctgccattca cagaagggga cattctggag
961 aaggtcagcg tgcattgccc tgtgtttgac tacgttcccc cagagctcat taccctcttt
1021 atctccaaca ttggtgggaa tgcaccttcc tacatctacc gcctgatgag tgaactctac
1081 catcctgatg atcatgtttt atgaccgacc acacgtgtcc taagcagatt gcttaggcag
1141 atacagaatg aagaggagac ttgagtgttg ctgctgaagc acatccttgc aatgtgggag
1201 tgcacaggag tccacctaaa aaaaaaatcc ttgatactgt tgcctgcctt tttagtcacc
1261 ccgtaacaag ggcacacatc caggactgtg tcttgccttt cagatcttaa cagagcagca
1321 gggcttaact tgttgatttt ggagcctctt agtgacctgg ttgcgtctgt gtcaggaact
1381 taaactttct ggttcagtag tgtgttaaac ataacactga ataccttact gggatacaga
1441 tttttgctca gaaatggcta tgacactttt tctaggctct accaataaaa gccacttgaa
1501 ggttcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
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