LOCUS BC000461 1264 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2, subunit 2
beta, 38kDa, mRNA (cDNA clone MGC:8508 IMAGE:2822324), complete
cds.
ACCESSION BC000461
VERSION BC000461.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1264)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1264)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000461.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: h Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29826334.
FEATURES Location/Qualifiers
source 1..1264
/db_xref="H-InvDB:HIT000029646"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8508 IMAGE:2822324"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1264
/gene="EIF2S2"
/gene_synonym="EIF2B"
/gene_synonym="EIF2beta"
/gene_synonym="MGC8508"
/db_xref="GeneID:8894"
/db_xref="HGNC:HGNC:3266"
/db_xref="MIM:603908"
CDS 137..1138
/gene="EIF2S2"
/gene_synonym="EIF2B"
/gene_synonym="EIF2beta"
/gene_synonym="MGC8508"
/codon_start=1
/product="eukaryotic translation initiation factor 2,
subunit 2 beta, 38kDa"
/protein_id="AAH00461.1"
/db_xref="GeneID:8894"
/db_xref="HGNC:HGNC:3266"
/db_xref="MIM:603908"
/translation="MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEV
EPEPTEDKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKDLK
IESDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEALEDEDNKKDDGISFS
NQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTS
FVNFTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIK
EYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN"
BASE COUNT 442 a 233 c 306 g 283 t
ORIGIN
1 ggtgtcgttt cctttcgctg atgcaagagc ctagtgcggt ggtgggagag gtatcggcag
61 gggcagcgct gccgccgggg cctggggctg acccgtctga cttcccgtcc gtgccgagcc
121 cactcgagcc gcagccatgt ctggggacga gatgattttt gatcctacta tgagcaagaa
181 gaaaaagaag aagaagaagc cttttatgtt agatgaggaa ggggataccc aaacagagga
241 aacccagcct tcagaaacaa aagaagtgga gccagagcca actgaggaca aggatttgga
301 agctgatgaa gaggacacta ggaaaaaaga tgcttctgat gatctagatg acttgaactt
361 ctttaatcaa aagaaaaaga agaaaaaaac taaaaagata tttgatattg atgaagctga
421 agaaggtgta aaggatctta agattgaaag tgatgttcaa gaaccaactg aaccagagga
481 tgaccttgac attatgcttg gcaataaaaa gaagaaaaag aagaatgtta agttcccaga
541 tgaggatgaa atactagaga aagatgaagc tctagaagat gaagacaaca aaaaagatga
601 tggtatctca ttcagtaatc agacaggccc tgcttgggca ggctcagaaa gagactacac
661 atacgaggag ctgctgaatc gagtgttcaa catcatgagg gaaaagaatc cagatatggt
721 tgctggggag aaaaggaaat ttgtcatgaa acctccacaa gtcgtccgag taggaaccaa
781 gaaaacttct tttgtcaact ttacagatat ctgtaaacta ttacatcgtc agcccaaaca
841 tctccttgca tttttgttgg ctgaattggg tacaagtggt tctatagatg gtaataacca
901 acttgtaatc aaaggaagat tccaacagaa acagatagaa aatgtcttga gaagatatat
961 caaggaatat gtcacttgtc acacatgccg atcaccggac acaatcctgc agaaggacac
1021 acgactctat ttcctacagt gcgaaacttg tcattctaga tgttctgttg ccagtatcaa
1081 aaccggcttc caggctgtca cgggcaagcg agcacagctc cgtgccaaag ctaactaatt
1141 tgctaatcac tgattttgca aagcttgttg tggagatgtg gctggacagg tttgccatca
1201 gagtggatat accgttgtat taaaaacaag ataaaaaagc tgccaaaaaa aaaaaaaaaa
1261 aaaa
//