LOCUS BC000442 1246 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens aurora kinase B, mRNA (cDNA clone MGC:8406
IMAGE:2820719), complete cds.
ACCESSION BC000442
VERSION BC000442.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1246)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1246)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Nov 6, 2003 this sequence version replaced BC000442.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: d Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4759177.
FEATURES Location/Qualifiers
source 1..1246
/db_xref="H-InvDB:HIT000029628"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8406 IMAGE:2820719"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1246
/gene="AURKB"
/gene_synonym="AIK2"
/gene_synonym="AIM-1"
/gene_synonym="AIM1"
/gene_synonym="ARK2"
/gene_synonym="AurB"
/gene_synonym="IPL1"
/gene_synonym="STK5"
/db_xref="GeneID:9212"
/db_xref="HGNC:HGNC:11390"
/db_xref="MIM:604970"
CDS 62..1096
/gene="AURKB"
/gene_synonym="AIK2"
/gene_synonym="AIM-1"
/gene_synonym="AIM1"
/gene_synonym="ARK2"
/gene_synonym="AurB"
/gene_synonym="IPL1"
/gene_synonym="STK5"
/codon_start=1
/product="aurora kinase B"
/protein_id="AAH00442.3"
/db_xref="GeneID:9212"
/db_xref="HGNC:HGNC:11390"
/db_xref="MIM:604970"
/translation="MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSR
SNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFI
VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG
ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIAD
FGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESA
SHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRV
LPPSALQSVA"
BASE COUNT 289 a 351 c 335 g 271 t
ORIGIN
1 gggcggccgg gagagtagca gtgccttgga ccccagctct cctccccctt tctctctaag
61 gatggcccag aaggagaact cctacccctg gccctacggc cgacagacgg ctccatctgg
121 cctgagcacc ctgccccagc gagtcctccg gaaagagcct gtcaccccat ctgcacttgt
181 cctcatgagc cgctccaatg tccagcccac agctgcccct ggccagaagg tgatggagaa
241 tagcagtggg acacccgaca tcttaacgcg gcacttcaca attgatgact ttgagattgg
301 gcgtcctctg ggcaaaggca agtttggaaa cgtgtacttg gctcgggaga agaaaagcca
361 tttcatcgtg gcgctcaagg tcctcttcaa gtcccagata gagaaggagg gcgtggagca
421 tcagctgcgc agagagatcg aaatccaggc ccacctgcac catcccaaca tcctgcgtct
481 ctacaactat ttttatgacc ggaggaggat ctacttgatt ctagagtatg ccccccgcgg
541 ggagctctac aaggagctgc agaagagctg cacatttgac gagcagcgaa cagccacgat
601 catggaggag ttggcagatg ctctaatgta ctgccatggg aagaaggtga ttcacagaga
661 cataaagcca gaaaatctgc tcttagggct caagggagag ctgaagattg ctgacttcgg
721 ctggtctgtg catgcgccct ccctgaggag gaagacaatg tgtggcaccc tggactacct
781 gcccccagag atgattgagg ggcgcatgca caatgagaag gtggatctgt ggtgcattgg
841 agtgctttgc tatgagctgc tggtggggaa cccacccttt gagagtgcat cacacaacga
901 gacctatcgc cgcatcgtca aggtggacct aaagttcccc gcttctgtgc ccacgggagc
961 ccaggacctc atctccaaac tgctcaggca taacccctcg gaacggctgc ccctggccca
1021 ggtctcagcc cacccttggg tccgggccaa ctctcggagg gtgctgcctc cctctgccct
1081 tcaatctgtc gcctgatggt ccctgtcatt cactcgggtg cgtgtgtttg tatgtctgtg
1141 tatgtatagg ggaaagaagg gatccctaac tgttccctta tctgttttct acctcctcct
1201 ttgtttaata aaggctgaag ctttttgtaa aaaaaaaaaa aaaaaa
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