LOCUS BC000402 1847 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens fusion (involved in t(12;16) in malignant
liposarcoma), mRNA (cDNA clone MGC:8537 IMAGE:2822692), complete
cds.
ACCESSION BC000402
VERSION BC000402.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1847)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1847)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000402.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: i Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 58218971.
FEATURES Location/Qualifiers
source 1..1847
/db_xref="H-InvDB:HIT000029590"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8537 IMAGE:2822692"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1847
/gene="FUS"
/gene_synonym="FUS-CHOP"
/gene_synonym="FUS1"
/gene_synonym="TLS"
/db_xref="GeneID:2521"
/db_xref="HGNC:HGNC:4010"
/db_xref="MIM:137070"
CDS 69..1649
/gene="FUS"
/gene_synonym="FUS-CHOP"
/gene_synonym="FUS1"
/gene_synonym="TLS"
/codon_start=1
/product="fusion (involved in t(12;16) in malignant
liposarcoma)"
/protein_id="AAH00402.1"
/db_xref="GeneID:2521"
/db_xref="HGNC:HGNC:4010"
/db_xref="MIM:137070"
/translation="MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQS
TDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQ
QPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQ
YNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGR
GGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD
SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLK
GEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPM
GRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAP
KPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGP
GKMDSRGEHRQDRRERPY"
BASE COUNT 451 a 422 c 599 g 375 t
ORIGIN
1 ctccaggcgt cggtgctcag cggtgttgga acttcgttgc ttgcttgcct gtgcgcgcgt
61 gcgcggacat ggcctcaaac gattataccc aacaagcaac ccaaagctat ggggcctacc
121 ccacccagcc cgggcagggc tattcccagc agagcagtca gccctacgga cagcagagtt
181 acagtggtta tagccagtcc acggacactt caggctatgg ccagagcagc tattcttctt
241 atggccagag ccagaacaca ggctatggaa ctcagtcaac tccccaggga tatggctcga
301 ctggcggcta tggcagtagc cagagctccc aatcgtctta cgggcagcag tcctcctatc
361 ctggctatgg ccagcagcca gctcccagca gcacctcggg aagttacggt agcagttctc
421 agagcagcag ctatgggcag ccccagagtg ggagctacag ccagcagcct agctatggtg
481 gacagcagca aagctatgga cagcagcaaa gctataatcc ccctcagggc tatggacagc
541 agaaccagta caacagcagc agtggtggtg gaggtggagg tggaggtgga ggtaactatg
601 gccaagatca atcctccatg agtagtggtg gtggcagtgg tggcggttat ggcaatcaag
661 accagagtgg tggaggtggc agcggtggct atggacagca ggaccgtgga ggccgcggca
721 ggggtggcag tggtggcggc ggcggcggcg gcggtggtgg ttacaaccgc agcagtggtg
781 gctatgaacc cagaggtcgt ggaggtggcc gtggaggcag aggtggcatg ggcggaagtg
841 accgtggtgg cttcaataaa tttggtggcc ctcgggacca aggatcacgt catgactccg
901 aacaggataa ttcagacaac aacaccatct ttgtgcaagg cctgggtgag aatgttacaa
961 ttgagtctgt ggctgattac ttcaagcaga ttggtattat taagacaaac aagaaaacgg
1021 gacagcccat gattaatttg tacacagaca gggaaactgg caagctgaag ggagaggcaa
1081 cggtctcttt tgatgaccca ccttcagcta aagcagctat tgactggttt gatggtaaag
1141 aattctccgg aaatcctatc aaggtctcat ttgctactcg ccgggcagac tttaatcggg
1201 gtggtggcaa tggtcgtgga ggccgagggc gaggaggacc catgggccgt ggaggctatg
1261 gaggtggtgg cagtggtggt ggtggccgag gaggatttcc cagtggaggt ggtggcggtg
1321 gaggacagca gcgagctggt gactggaagt gtcctaatcc cacctgtgag aatatgaact
1381 tctcttggag gaatgaatgc aaccagtgta aggcccctaa accagatggc ccaggagggg
1441 gaccaggtgg ctctcacatg gggggtaact acggggatga tcgtcgtggt ggcagaggag
1501 gctatgatcg aggcggctac cggggccgcg gcggggaccg tggaggcttc cgagggggcc
1561 ggggtggtgg ggacagaggt ggctttggcc ctggcaagat ggattccagg ggtgagcaca
1621 gacaggatcg cagggagagg ccgtattaat tagcctggct ccccaggttc tggaacagct
1681 ttttgtcctg tacccagtgt taccctcgtt attttgtaac cttccaattc ctgatcaccc
1741 aagggttttt ttgtgtcgga ctatgtaatt gtaactatac ctctggttcc cattaaaagt
1801 gaccatttta gttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//